There's a fantastic documentary called "Icarus" about the Russian doping program. It starts about being about the filmmaker's doping experience while riding in the 7 day Haute Route. He rides the first year clean and finished 14th. Then he starts an organized doping program (EPO and other stuff) under professional guidance. In the second year, he finished in the mid-20's even though his watts and power were way higher. That's an amateur race, so no where near the level Armstrong competed in. The filmmaker said there were always 8-10 guys at the top of the amateur classification that no one could touch. Its just one anecdotal example, but the point I think is accepted - you can't compete at a high level without the drugs, but drugs alone, even for a top rider, don't guarantee results. All of US Postal was on Lance's program for years. Maybe Hincapie, Hamilton or Leipheimer could have won in one of those years (all doping), but none of them could do what Armstrong did - no one was close. Ullrich, Beloki, Pantanini, Kloden, Vinokourov, Basso - all the top riders Armstrong competed against in those years were eventually busted.