Also, the area is heavily policed and has a high % of DUIs. Don't put yourself in a bad position.
I have the advantage of being in the heart of it and over the years my best experiences have been finding a few that your really like and being able to linger with staff talking about the wines and vineyards. There is no need to do a blitz. Do 1-2 in the morning. Grab a nice lunch somewhere and see where you are... maybe 1-2 more afterwards. Left turns can be a bear, so you may want to plan accordingly (wineries on the east side first, then west side on the way