It really doesn't matter most of the time in an 8 team league. If you start 9 spots and have 16 to 18 man rosters there is always going to be good players on the waiver wire.
This is oversimplifying it. The draft matters. If you have a normal lineup, everyone will have studs, but some studs are more reliable than others. In my past experience in 8 team leagues, it's sometimes hard to anticipate runs if you're on one end of the draft. I like to draft in a middle spot and watch the trends.If you're in a deep lineup such as 2QB, 3RB, 4WR, etc., these are really challenging leagues and being in the middle is even more important avoid the run problem.