[SIZE=10.5pt]
Tissue engineered hearts http://www.iflscience.com/health-and-medicine/beating-artificial-heart-tissue-announcedand
lungs [/SIZE]may be still at the laboratory stage, but replacement ######s made from the patient's own cells have been around for a while. A paper in
the Lancet confirms they continue to work years after surgery.
[SIZE=10.5pt]
The four patients in the study had Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome, which affects women who are genetically and hormonally normal but have an absent or greatly shortened ######. MRKH may also produce a missing or defective cervix and uterus. Sex is usually painful for women with the condition and more than half a million are affected worldwide.[/SIZE]
[SIZE=10.5pt]
While we are some way from being able to enable women most with MRKH to conceive, the Wake Forest School of Medicine created sheets from biodegradable scaffolds and epithelial and muscle cells of four girls aged 13-18 with MRKH. These were then “hand-sewn into a ######-like shape” in the authors' words and implanted. Each ###### was shaped by the Federico Gomez Children's Hospital, Mexico, to best match the body of the woman it was for.[/SIZE]
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Follow-ups over the next 6-8 years using physical examination, tissue biopsies and MRIs indicated that blood vessels had connected to the implant and within months new cells formed spontaneously while the scaffold was slowly absorbed. A tri-layered structure remained in place after the scaffolding was gone and no abnormalities were observed. The women responded to a questionnaire with responses in the normal range in regard to arousal, lubrication, orgasm and painless intercourse. Most significantly, the patients reported high satisfaction with the replacement ######s.[/SIZE]
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Other existing treatments for MRKH are much more traumatic and have a high rate of failure and complication. Team leader Anthony Atala has used a similar technique to build replacement bladders for nine children in need, and has implanted urethras in boys, although there is yet to be the long-term confirmation of success in that case.[/SIZE]
Tissue engineered
hearts and
lungs may be still at the laboratory stage, but replacement ######s made from the patient's own cells have been around for a while. A paper in
the Lancet confirms they continue to work years after surgery.
The four patients in the study had Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome, which affects women who are genetically and hormonally normal but have an absent or greatly shortened ######. MRKH may also produce a missing or defective cervix and uterus. Sex is usually painful for women with the condition and more than half a million are affected worldwide.
While we are some way from being able to enable women most with MRKH to conceive, the Wake Forest School of Medicine created sheets from biodegradable scaffolds and epithelial and muscle cells of four girls aged 13-18 with MRKH. These were then “hand-sewn into a ######-like shape” in the authors' words and implanted. Each ###### was shaped by the Federico Gomez Children's Hospital, Mexico, to best match the body of the woman it was for.
Follow-ups over the next 6-8 years using physical examination, tissue biopsies and MRIs indicated that blood vessels had connected to the implant and within months new cells formed spontaneously while the scaffold was slowly absorbed. A tri-layered structure remained in place after the scaffolding was gone and no abnormalities were observed. The women responded to a questionnaire with responses in the normal range in regard to arousal, lubrication, orgasm and painless intercourse. Most significantly, the patients reported high satisfaction with the replacement ######s.
Other existing treatments for MRKH are much more traumatic and have a high rate of failure and complication. Team leader Anthony Atala has used a similar technique to build replacement bladders for nine children in need, and has implanted urethras in boys, although there is yet to be the long-term confirmation of success in that case.
Read more at
http://www.iflscience.com/health-and-medicine/laboratory-grown-######s-succesfully-transplanted-patients#6SuqIjI7wPgbdEBY.99Tissue engineered
hearts and
lungs may be still at the laboratory stage, but replacement ######s made from the patient's own cells have been around for a while. A paper in
the Lancet confirms they continue to work years after surgery.
The four patients in the study had Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome, which affects women who are genetically and hormonally normal but have an absent or greatly shortened ######. MRKH may also produce a missing or defective cervix and uterus. Sex is usually painful for women with the condition and more than half a million are affected worldwide.
While we are some way from being able to enable women most with MRKH to conceive, the Wake Forest School of Medicine created sheets from biodegradable scaffolds and epithelial and muscle cells of four girls aged 13-18 with MRKH. These were then “hand-sewn into a ######-like shape” in the authors' words and implanted. Each ###### was shaped by the Federico Gomez Children's Hospital, Mexico, to best match the body of the woman it was for.
Follow-ups over the next 6-8 years using physical examination, tissue biopsies and MRIs indicated that blood vessels had connected to the implant and within months new cells formed spontaneously while the scaffold was slowly absorbed. A tri-layered structure remained in place after the scaffolding was gone and no abnormalities were observed. The women responded to a questionnaire with responses in the normal range in regard to arousal, lubrication, orgasm and painless intercourse. Most significantly, the patients reported high satisfaction with the replacement ######s.
Other existing treatments for MRKH are much more traumatic and have a high rate of failure and complication. Team leader Anthony Atala has used a similar technique to build replacement bladders for nine children in need, and has implanted urethras in boys, although there is yet to be the long-term confirmation of success in that case.
Read more at
http://www.iflscience.com/health-and-medicine/laboratory-grown-######s-succesfully-transplanted-patients#6SuqIjI7wPgbdEBY.99Tissue engineered
hearts and
lungs may be still at the laboratory stage, but replacement ######s made from the patient's own cells have been around for a while. A paper in
the Lancet confirms they continue to work years after surgery.
The four patients in the study had Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome, which affects women who are genetically and hormonally normal but have an absent or greatly shortened ######. MRKH may also produce a missing or defective cervix and uterus. Sex is usually painful for women with the condition and more than half a million are affected worldwide.
While we are some way from being able to enable women most with MRKH to conceive, the Wake Forest School of Medicine created sheets from biodegradable scaffolds and epithelial and muscle cells of four girls aged 13-18 with MRKH. These were then “hand-sewn into a ######-like shape” in the authors' words and implanted. Each ###### was shaped by the Federico Gomez Children's Hospital, Mexico, to best match the body of the woman it was for.
Follow-ups over the next 6-8 years using physical examination, tissue biopsies and MRIs indicated that blood vessels had connected to the implant and within months new cells formed spontaneously while the scaffold was slowly absorbed. A tri-layered structure remained in place after the scaffolding was gone and no abnormalities were observed. The women responded to a questionnaire with responses in the normal range in regard to arousal, lubrication, orgasm and painless intercourse. Most significantly, the patients reported high satisfaction with the replacement ######s.
Other existing treatments for MRKH are much more traumatic and have a high rate of failure and complication. Team leader Anthony Atala has used a similar technique to build replacement bladders for nine children in need, and has implanted urethras in boys, although there is yet to be the long-term confirmation of success in that case.
Read more at
http://www.iflscience.com/health-and-medicine/laboratory-grown-######s-succesfully-transplanted-patients#6SuqIjI7wPgbdEBY.99
