I rarely have more than one DST on my team. I try to stream Ds based on match-up groupings. For instance, I picked up CIN DST in the draft. I didn't expect them to get lit up by BAL, but figured I'd be a bit behind in week one, but with four of their next five games against three of the worst offensive units (2 vs. CLE, MIA, JAX), I figured it was worth a shot. The fifth game is vs. WAS. Come week six, I might drop my back-up TE or QB to get an early jump on DSTs for week 7+. If I luck out and get a big time D (last year, it was SF), then I'll roll through a few iffy games to keep them or maybe stream an extra roster spot for match-ups, but I'll sort that out later.