I'm sure this is said every year when we discuss similar topics, but aside from injury I can't imagine a situation where any of these top 4 are not in the top 10. Zeke will always get his carries, CMC catches everything so even if the TDs drop he'll be a great player, Barkley is incredible; aside from the Giants just being so awful he can't carry them he'll be in the top 10, and Kamara is so dynamic he too gets his catches, carries and some TDs. I'm not saying it's impossible, but it is difficult to see barring injury that one of these guys is not top 10. But as I stated before, I'm sure this is said every year.