Overreacting a bit for a sore underarm? That's causing you regret?####
My lymph nodes in my underarm in the arm I got the booster are swollen and sore. Is this normal? I should've never gotten this booster yet. ####
It is. Swollen lymph nodes are one of many possible immune reactions.My lymph nodes in my underarm in the arm I got the booster are swollen and sore. Is this normal?
I doubt mixing Moderna and Pfizer would do much harm or give significant benefit. From available information it looks like Moderna is the winner so far with longer lasting immunity and better coverage against Delta. My thought is that this is mainly due to the higher dose than superiority of Moderna with efficacy balancing out with the boosters.Having gotten the Pfizer shot 1&2 in the spring, been waiting to see if there is any benefit to looking for a Moderna version for the booster over just sticking with Pfizer. Not quite due yet, so just waiting on the science to say one way or the other. I may not end up having much choice though, I don't see many (if any) places offering Moderna around my area anyways. I thought I'd read at one point they thought there might be broader immune response by mixing it up, but I feel like they walked that back a bit since then.
Also also watching to see if they decide to release a separate booster rather than a 3rd shot that is the same as the previous two (i.e. to better target some of the variants). But feels like that is 1) not necessary so far and 2) probably a ways out cause it'd need more testing.
See you didn’t wait to hear my advice and that’s what happens! I would have told you get both, so it wouldn’t have mattered. Lymph node swelling while weird is a semi-common reaction. Nothing to worry about, will probably resolve in a couple days and just a sign your immune system is building good COVID stopping troops.####
My lymph nodes in my underarm in the arm I got the booster are swollen and sore. Is this normal? I should've never gotten this booster yet. ####
Yeah you took too long lolSee you didn’t wait to hear my advice and that’s what happens! I would have told you get both, so it wouldn’t have mattered. Lymph node swelling while weird is a semi-common reaction. Nothing to worry about, will probably resolve in a couple days and just a sign your immune system is building good COVID stopping troops.
Yeah work is hell right now. We’re so understaffed and overworked that it’s become dangerous. And somehow we’re not doing enough.Yeah you took too long lol
The pain is pretty severe. It scared me because it didn't happen my first two shots.
Best wishes to your family.My cousin and her family are all anti-vax. Her 16 yo daughter has pretty serious heart problems, and now she has Covid. All of a sudden my cousin is texting us all to tell us we should take Covid seriously.
(“You stay healthy too. Keep a close eye on your family this is no joke! This Covid is BAD NEWS!! Love you all!!”)
I’m not going to lecture her, just going to encourage them all to do whatever the doctors say, including to get vaccinated when appropriate. As of now, my cousin and her husband haven’t tested positive. But her daughter has been really sick the past 2-3 days.
Good thing you don't work for him anymore.My ex-boss just sent me a link to a video
There’s a bunch of personality disorders, which are characterized by traits you may see even in “normal” people. A disorder is present only when the traits hinder ones functioning in society, particularly interpersonal relationships.My ex-boss just sent me a link to a video from the Stew Peters Show. Never heard of the guy but he was adamant I watch it because it proves without a shadow of a doubt that the vaccines are being used as manipulation of the population and the enforcement of behavioral modification. I won't post this stuff here but he legit believes this is what's going on and that the deep state is coming for me & you and using this pandemic as a way to get there. He also believes the vaccine is injecting some kind of electronic tracking via a method called Electroporation.
There are thousands upon thousands who believe this stuff. I can't believe the conviction these people have.
You know I had this also. I didn't associate with the booster shot but it seems possible now that you mention it.####
My lymph nodes in my underarm in the arm I got the booster are swollen and sore. Is this normal? I should've never gotten this booster yet. ####
Did it go away?You know I had this also. I didn't associate with the booster shot but it seems possible now that you mention it.
Yeah took about five or sis days from appearance to mostly gone. Had one big one in left pit and much smaller one in right pit. Stung like all get out forms day or two and then pretty well gone. I’m going in to get double checked just in case. Hate to mistake some thing else for a vaccine side effect.Did it go away?
I did just read somewhere that the booster is more likely to cause swollen lymph nodes than the first or second shot was.Yeah took about five or sis days from appearance to mostly gone. Had one big one in left pit and much smaller one in right pit. Stung like all get out forms day or two and then pretty well gone. I’m going in to get double checked just in case. Hate to mistake some thing else for a vaccine side effect.
I don't know how easily this could be done but I sure like the idea. It's information-based, allows people to assess themselves objectively to go along with their subjective feelings.I wouldn’t mind seeing them coming up with risk scale to help people decide if they need a booster shot. Use age, health conditions and exposure risk to give you a risk score and help you decide if you need to get the booster.
It actually would have been nice to see such a matrix basically anytime in the past 18 months. No idea why our public health officials couldn’t pull that together…..ever.fatness said:I don't know how easily this could be done but I sure like the idea. It's information-based, allows people to assess themselves objectively to go along with their subjective feelings.
It actually would have been nice to see such a matrix basically anytime in the past 18 months. No idea why our public health officials couldn’t pull that together…..ever.
Honestly we could probably do it. The data is out there. Would involve some interpolation and educated guessing, but you could likely build out a efficacy curve for each vax, then factor in comorbidity risk factors as they've been loosely quantified.It actually would have been nice to see such a matrix basically anytime in the past 18 months. No idea why our public health officials couldn’t pull that together…..ever.
The most recent studies suggest that hybrid immunity is, at least partly, due to immune players called memory B cells. The bulk of antibodies made after infection or vaccination come from short-lived cells called plasmablasts, and antibody levels fall when these cells inevitably die off. Once plasmablasts are gone, the main source of antibodies becomes much rarer memory B cells that are triggered by either infection or vaccination.
Some of these long-lived cells make higher-quality antibodies than plasmablasts, says Michel Nussenzweig, an immunologist at the Rockefeller. That’s because they evolve in organs called lymph nodes, gaining mutations that help them to bind more tightly to the spike protein over time. When people who recovered from COVID-19 are re-exposed to SARS-CoV-2’s spike, these cells multiply and churn out more of these highly potent antibodies.
“You get a sniff of antigen, in this case of mRNA vaccine, and those cells just explode,” says Goel. In this way, a first vaccine dose in someone who has previously been infected is doing the same job as a second dose in someone who has never had COVID-19.
Nathan R. Jessep said:good piece on immunity (vaccine, natural, and hybrid):
COVID super-immunity: one of the pandemic’s great puzzles
The red above addresses the question I have. If you are vaccinated, then get an infection (even if no symptoms), are you now TeamHybridImmunity? I guess that's what they're trying to answer.
- Differences between the memory B cells triggered by infection and those triggered by vaccination — as well as the antibodies they make — might also underlie the heightened responses of hybrid immunity. Infection and vaccination expose the spike protein to the immune system in vastly different ways, Nussenzweig says.
- There is some evidence that people who received both jabs without previously being infected seem to be catching up. Ellebedy’s team collected lymph-node samples from mRNA-vaccinated individuals and found signs that some of their memory B cells triggered by the vaccination were gaining mutations, up to 12 weeks after the second dose, that enabled them to recognize diverse coronaviruses, including some that cause common colds.
- A third vaccine dose might allow people who haven't been infected to achieve the benefits of hybrid immunity, says Matthieu Mahévas, an immunologist at the Necker Institute for Sick Children in Paris. His team found that some of the memory B cells from naive vaccine recipients could recognize Beta and Delta, two months after vaccination
- Extending the interval between vaccine doses could also mimic aspects of hybrid immunity. In 2021, amid scarce vaccine supplies and a surge in cases, officials in the Canadian province of Quebec recommended a 16-week interval between first and second doses (since reduced to 8 weeks).
- As breakthrough infections caused by the Delta variant stack up, researchers including Nussenzweig are keen to study the immunity in people who were infected after their COVID-19 vaccinations, rather than before. An individual’s first exposure to influenza virus biases their responses to subsequent exposures and vaccinations — a phenomenon called original antigenic sin — and researchers want to know if this occurs with SARS-CoV-2.
- Those studying hybrid immunity stress that — whatever the potential benefits — the risks of a SARS-CoV-2 infection mean that it should be avoided. “We are not inviting anybody to get infected and then vaccinated to have a good response,” says Finzi. “Because some of them will not make it through.”
@beer 30 and anyone else who might know... this is good, right?
Air Quality & Filtration
... [big venue] is outfitted with MERV-13 filtration, which exceeds suggested minimum guidelines. As an additional protective measure, we have tested and balanced the entire ventilation system to ensure maximum number of air exchanges in all occupied spaces.
Abstract
The durability of immune memory after SARS-CoV-2 mRNA vaccination remains unclear. Here, we longitudinally profiled vaccine responses in SARS-CoV-2 naïve and recovered individuals for 6 months after vaccination. Antibodies declined from peak levels but remained detectable in most subjects at 6 months. We found mRNA vaccines generated functional memory B cells that increased from 3-6 months post-vaccination, with the majority of these cells cross-binding the Alpha, Beta, and Delta variants. mRNA vaccination further induced antigen-specific CD4+ and CD8+ T cells, and early CD4+ T cell responses correlated with long-term humoral immunity. Recall responses to vaccination in individuals with pre-existing immunity primarily increased antibody levels without substantially altering antibody decay rates. Together, these findings demonstrate robust cellular immune memory to SARS-CoV-2 and variants for at least 6 months after mRNA vaccination.
As @[icon]said it’s good. It’s not as good as HEPA but it’s better than nothing.@beer 30 and anyone else who might know... this is good, right?
Air Quality & Filtration
... [big venue] is outfitted with MERV-13 filtration, which exceeds suggested minimum guidelines. As an additional protective measure, we have tested and balanced the entire ventilation system to ensure maximum number of air exchanges in all occupied spaces.
Too many variables: comorbidities, exposure risk, viral strains, vaccine choice, durability of immunity and a changing population of vulnerable people, to name a few.It actually would have been nice to see such a matrix basically anytime in the past 18 months. No idea why our public health officials couldn’t pull that together…..ever.
I think that's likely the point. If they have risk strata then some people will interpret that as "I don't need to get a vaccine." That's not a good thing if a) the vaccine is safe and b) vaccinating as many people as possible helps those who can't get it or who didn't mount a sufficient immune response and are not well prepared for an exposure.While I agree healthcare is too opaque, rolling out a complex risk stratification tool for public consumption during a novel pandemic would not improve (and would probably impede) vaccine uptake IMO.
Yep. And they’ll probably fail to adjust their risk assessment as the pandemic, and our understanding, evolves.I think that's likely the point. If they have risk strata then some people will interpret that as "I don't need to get a vaccine." That's not a good thing if a) the vaccine is safe and b) vaccinating as many people as possible helps those who can't get it or who didn't mount a sufficient immune response and are not well prepared for an exposure.
Ugh. I'm sad for him and his family, obviously. Worried that this will further vaccine hesitancy for a prominent person, an African-American no less, to die after being vaccinated. But what has me the most upset at this news is that my best friend in the world, like Powell, has multiple myeloma. He appears to be in remission at the moment and was finally able to get his second shot last month -- and, as an otherwise healthy guy in his 40s, is obviously much lower risk than Powell -- but this is a reminder that people like him can never totally let their guard down.Colin Powell dies from Covid while fully vaxxed, at age 84. Ugh.
Was just going to comment on your first post but you summed it up nicely here. There is no nuance and unfortunately with a novel virus, you need to understand nuance. It's not black & white, some people are just going to die from this thing no matter what they do. As you said, that will be lost and more people will jump into the vaccine bad boat.It's a cruel irony that many people's takeaway from this Powell news will be "What's the point of getting vaccinated?" instead of "It's even more important for me to get vaccinated to protect high-risk people like him."
Ugh. I'm sad for him and his family, obviously. Worried that this will further vaccine hesitancy for a prominent person, an African-American no less, to die after being vaccinated. But what has me the most upset at this news is that my best friend in the world, like Powell, has multiple myeloma. He appears to be in remission at the moment and was finally able to get his second shot last month -- and, as an otherwise healthy guy in his 40s, is obviously much lower risk than Powell -- but this is a reminder that people like him can never totally let their guard down.
As soon as I saw this link, I knew it was about Centner. This school went viral (metaphorically, but probably literally as well) earlier this year when they announced they would fire teachers who did get vaxxed. Turns out it was founded by a crazy couple who was full-on anti-vax long before anyone had heard of Covid. This is par for the courseFlorida school won’t allow vaxed students to go to school until 30 days after each dose.
Someone there seems to think that vaccinated people have the live virus in them that they can then pass to other people. Or, more likely IMO, they just are total anti-vaxxers knowingly making stuff up in order to make some sort of stupid point and make life difficult for people who get vaccinated.
See if you can pick up BinaxNow home test kits. That's what a lot of the clinics around here are using for rapid tests. Our Walmart has them (when in stock) for $14 for a 2-test box. Several of the pharmacies carry them also, although a little more expensive than WM.So for pretty much the first time since this crap started one of us is sick. Twelvr year old started having stuffy nose and low grade fever on Saturday. Been about the same since. Says nose is a little better this morning. Temp staying at 99.9. Stayed home from school today. I'm guessing she caught something last week at school from someone who picked up something over fall break. I thought I might have been coming down with a little something too but now I'm thinking mine is just lack of sleep catching up to me.
At what point is a Covid test necessary? I called around hoping to get a rapid one somewhere but nothing was open that offered yesterday when I was looking. The PCR ones take a couple days for results right? If symptoms don't get worst just ride it out? Forgot to add we are all fully 2 dose pfizered.
Good info thanks.See if you can pick up BinaxNow home test kits. That's what a lot of the clinics around here are using for rapid tests. Our Walmart has them (when in stock) for $14 for a 2-test box. Several of the pharmacies carry them also, although a little more expensive than WM.
ETA: Hope everyone gets to feeling better.
See if you can pick up BinaxNow home test kits. That's what a lot of the clinics around here are using for rapid tests. Our Walmart has them (when in stock) for $14 for a 2-test box. Several of the pharmacies carry them also, although a little more expensive than WM.
ETA: Hope everyone gets to feeling better.
Maybe you should read the recent Harvard study.Florida school won’t allow vaxed students to go to school until 30 days after each dose.
Someone there seems to think that vaccinated people have the live virus in them that they can then pass to other people. Or, more likely IMO, they just are total anti-vaxxers knowingly making stuff up in order to make some sort of stupid point and make life difficult for people who get vaccinated.
With two kids that have had Covid, I would say this is not it. It gets worse fast and does not remain the same. I think the fever would be higher also.So for pretty much the first time since this crap started one of us is sick. Twelvr year old started having stuffy nose and low grade fever on Saturday. Been about the same since. Says nose is a little better this morning. Temp staying at 99.9. Stayed home from school today. I'm guessing she caught something last week at school from someone who picked up something over fall break. I thought I might have been coming down with a little something too but now I'm thinking mine is just lack of sleep catching up to me.
At what point is a Covid test necessary? I called around hoping to get a rapid one somewhere but nothing was open that offered yesterday when I was looking. The PCR ones take a couple days for results right? If symptoms don't get worst just ride it out? Forgot to add we are all fully 2 dose pfizered.
Maybe you should read the recent Harvard study.
This. BinaxNOW Tests are certainly not PCR tests, but they're quite good at identifying established infection. If you are symptomatic and test negative, you can be reasonably sure you're negative. If you test positive you can be almost certain you're positive.
We have about a half dozen of the kits on hand at the house, use them as needed (and share with friends when needed).
Also, there are rapid PCR tests now. Not all clinics are set up for it, but many are.
There is a Harvard study that says getting the vaccine makes you contagious? This literally makes no sense at all.Maybe you should read the recent Harvard study.
I just recovered from a mild case of COVID, where I received the J&J shot in April. I am now indestructible.good piece on immunity (vaccine, natural, and hybrid):
COVID super-immunity: one of the pandemic’s great puzzles
The red above addresses the question I have. If you are vaccinated, then get an infection (even if no symptoms), are you now TeamHybridImmunity? I guess that's what they're trying to answer.
- Differences between the memory B cells triggered by infection and those triggered by vaccination — as well as the antibodies they make — might also underlie the heightened responses of hybrid immunity. Infection and vaccination expose the spike protein to the immune system in vastly different ways, Nussenzweig says.
- There is some evidence that people who received both jabs without previously being infected seem to be catching up. Ellebedy’s team collected lymph-node samples from mRNA-vaccinated individuals and found signs that some of their memory B cells triggered by the vaccination were gaining mutations, up to 12 weeks after the second dose, that enabled them to recognize diverse coronaviruses, including some that cause common colds.
- A third vaccine dose might allow people who haven't been infected to achieve the benefits of hybrid immunity, says Matthieu Mahévas, an immunologist at the Necker Institute for Sick Children in Paris. His team found that some of the memory B cells from naive vaccine recipients could recognize Beta and Delta, two months after vaccination
- Extending the interval between vaccine doses could also mimic aspects of hybrid immunity. In 2021, amid scarce vaccine supplies and a surge in cases, officials in the Canadian province of Quebec recommended a 16-week interval between first and second doses (since reduced to 8 weeks).
- As breakthrough infections caused by the Delta variant stack up, researchers including Nussenzweig are keen to study the immunity in people who were infected after their COVID-19 vaccinations, rather than before. An individual’s first exposure to influenza virus biases their responses to subsequent exposures and vaccinations — a phenomenon called original antigenic sin — and researchers want to know if this occurs with SARS-CoV-2.
- Those studying hybrid immunity stress that — whatever the potential benefits — the risks of a SARS-CoV-2 infection mean that it should be avoided. “We are not inviting anybody to get infected and then vaccinated to have a good response,” says Finzi. “Because some of them will not make it through.”
Fever 100.6 now but says nose is not as runny. Going to Walmart to try pick up a couple of these tests at lunch time.With two kids that have had Covid, I would say this is not it. It gets worse fast and does not remain the same. I think the fever would be higher also.
They are not vaccinated so there is that. Either way hope she gets to feeling better.
It says that only after going through the contortions of misrepresentation and misinterpretation by the anti-vax usual suspects. Anything to sow doubt and misinformation.There is a Harvard study that says getting the vaccine makes you contagious? This literally makes no sense at all.Maybe you should read the recent Harvard study.