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What would you do if you were bit by this? (1 Viewer)

Don't Toews Me

Footballguy
Boy survives bite from super deadly spider thanks to quick-thinking dad

A 10-year-old Australian boy has survived a bite from one of the world’s deadliest spiders after taking a record 12 vials of anti-venom, local media reported.

Matthew Mitchell was helping his dad clear out the back shed at their home north of Sydney when he was bitten on the finger by a funnel-web spider that had been lurking in his shoe.

“It sort of clawed onto me and all the legs and everything crawled around my finger and I couldn’t get it off,” he told the Australian Daily Telegraph.

His family used his shirt as a compression bandage to try to slow the venom’s spread and rushed him to a hospital.

He experienced convulsions but survived after being given 12 vials of anti-venom, which local media said was an Australian record.

The funnel-web spider is among the world’s deadliest spiders. Its venom attacks the nervous system, causing foaming at the mouth, muscle spasms and potentially death.

The spider was caught and taken to the Australian Reptile Park, where it will be milked as part of their program to develop anti-venom.

The 10-year-old was “as lucky as they get,” Australian Reptile Park general manager Tim Faulkner told The Telegraph.

Australia is home to a startling number of the world’s deadliest creatures, including snakes, spiders, jellyfish and octopuses.

The funnel-web is particularly feared, but no deaths have been recorded since the anti-venom was developed in the 1980s.

In December, a 5-year-old girl was rushed to a hospital with a swollen leg after suffering a severe allergic reaction to a spider bite.

Lola Hutton came home from school complaining of an itchy leg and within hours she had developed an agonizing lump “about half the size of a Ferrero Rocher,” a round chocolate treat a little smaller than a ping-pong ball.
There's a picture of the type of spider at the link for those brave enough.

 
I'd wait for my mutant super powers to kick in. 

"Hey, I feel my spider-sense tingling.  :)

Oh, wait, that's just the neurotoxin.  :shock: :X "

 
Interesting if true (my knowledge on the following subject is minimal):

"Deadly spider venom could ward off stroke brain damage, say doctors"

Doctors have stumbled on an unlikely source for a drug to ward off brain damage caused by strokes: the venom of one of the deadliest spiders in the world.

A bite from an Australian funnel web spider can kill a human in 15 minutes, but a harmless ingredient found in the venom can protect brain cells from being destroyed by a stroke, even when given hours after the event, scientists say.

If the compound fares well in human trials, it could become the first drug that doctors have to protect against the devastating loss of neurons that strokes can cause.

Researchers discovered the protective molecule by chance as they sequenced the DNA of toxins in the venom of the Darling Downs funnel web spider (Hadronyche infensa) that lives in Queensland and New South Wales.

Venom from three spiders was gathered for the study after scientists trapped and “milked exhaustively” three spiders on Orchid beach, about 400km north of Brisbane.

The molecule, called Hi1a, stood out because it looked like two copies of another brain cell-protecting chemical stitched together. It was so intriguing that scientists decided to synthesise the compound and test its powers. “It proved to be even more potent,” said Glenn King at the University of Queensland’s centre for pain research.

Strokes occur when blood flow to the brain is interrupted and the brain is starved of oxygen. About 85% of strokes are caused by blockages in blood vessels in the brain, with the rest due to bleeds when vessels rupture. Approximately six million people a year die from stroke, making it the second largest cause of death worldwide after heart attacks.

When a stroke happens, the oxygen level in the brain drops. This forces the brain to burn its primary fuel, glucose, very differently. Instead of oxidising glucose for energy, the brain switches to a process called anaerobic glycolysis. The reaction releases energy to keep the brain working, but it also produces acid, which can cause brain cells to die.

In a series of studies on rats, King showed that a single small dose of the spider venom molecule protected neurons from induced strokes. The compound works by blocking what are called ion channels in cells, specifically those that respond to the onset of acidic conditions in the brain.

Reporting in the journal, Proceedings of the National Academy of Sciences, King describes how administering Hi1a two hours after stroke reduced the extent of brain damage in rats by 80%. But the compound was still effective eight hours after stroke, reducing the amount of brain damage by about 65% when compared with untreated animals.

Rats that had the compound recovered far better than those that went without. “The untreated rats performed very badly after stroke. Their neurological and motor performance were terrible,” said King. But treatment with Hi1a “almost restored these functions to normal,” he added.

The researchers hope to start human trials of the compound in the next two years, but have more experiments to perform first. These will test whether the molecule works in all cases of stroke and is safe to use when blood vessels rupture in the brain, rather than become blocked. In the latest study, the compound was infused directly into the brain, but the scientists have found since that nasal deliver works too.

If trials show that the compound works, it could potentially transform the treatment of stroke patients. There are no drugs on the market that can protect the brain from stroke injuries. The best hospitals can offer are infusions of clot-busting drugs if a clot is to blame, or a surgical procedure called endovascular thrombectomy, which physically pulls the clot from the brain.

Before doctors can administer clot-busting drugs, they must confirm with a brain scan that the stroke was caused by a blockage. This is because the treatment thins the blood and could make matters worse if the stroke was caused by a haemorrhage. If Hi1a is found to be safe for people who have had with brain bleeds, it could be given to patients as soon as they reach a doctor. “The drug could be given in the ambulance to most stroke patients before hospital arrival, maximising the number of neurons that can be saved,” said King. “This should diminish the mortality from stroke and provide much better outcomes for those that survive as more brain function will be retained.”

Kate Holmes at the Stroke Association, said it was unknown whether Hi1a could be an effective treatment in humans. “We welcome any treatment that has the potential to reduce the damage caused by stroke, particularly if this can benefit people who are unable to arrive at hospital quickly,” she added. “Current treatments must be given in half this time period and it is too early for us to know if this research can offer an alternative for stroke patients.

“We urge for stroke to be treated as an emergency. The sooner a person can get to hospital after a stroke, the sooner the right treatment can be received which can improve survival and help recovery,” she said.



 

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