Yes. I drafted both Lynch and MJD in an initial dynasty draft this past offseason. I "reached" for Jones-Drew with the 13th overall selection while there were much "better" choices left on the board. During the course of the season, I had to trade him straight up for Randy Moss in order to gear up for my championship run, and despite seeing drastic and immediate dividends from the trade and becoming clearly the best team in the league, I still regret it. The MJD owner wound up with the first and third rookie picks (which will probably become McFadden and Mendenhall) and he owns a couple of other young RBs, so I've been trying to pry MJD back away, but he won't let him go. I already offered Lynch for MJD straight up, but was turned down.
Here's what it comes down to for me- in the end, talent wins out, and outside of Peterson, I don't think there's a single RB under the age of 27 in the entire NFL who is more talented than Maurice Jones-Drew. That includes Steven Jackson and Frank Gore, as well as all of the incoming rookies. I think both Jackson and Gore are special talents, and I think that both are probably more ideally suited for a massive workload than MJD, but outside of Brian Westbrook, nobody in the league brings such a wide array of fully developed tools to the table as Jones-Drew. He excels in all three facets of the game- running, receiving, and blocking. He even excels in all of the facets of those facets. He can run with vision through traffic, he can run with speed in the open field, he can run with power and initiate contact, he can run with creativity and avoid contact. He runs great routes, has great hands, is very smart, has great field awareness, and is a devastating blocker. He has patience to wait for his blocks to develop, confidence to make something out of nothing, and wisdom to just get what he can when there's nothing else he can do. And his body type, which was seen as a disadvantage coming out, proves to be a big advantage- it makes him harder to locate in traffic (as evidenced by his ridiculous "fall down and then run untouched to the end zone" play against the Patriots his rookie year), and he always has a leverage advantage because it's impossible for a tackler to get below his pads. MJD is quite simply one of the most obscene talents in the entire NFL, and I have confidence that over the long run, that talent is going to shine through.
As for Marshawn Lynch, I haven't seen anything from him to suggest that he's anything more than just another very good back, another Joseph Addai, Chris Perry, Kevin Jones, LaMont Jordan, Willie Parker, etc. He might continue developing and one day become a stud nonpareil, but in the meantime, he's just another very good back in a long line of very good back. Traditionally, very good backs don't have elite value unless they're paired with a very good system (see: Addai, Joseph), and I'm not convinced that Buffalo is going to be a long-term rushing hotspot. I'm glad that I own Lynch because he should be a reliable RB2 for the next 3+ years for me, but if given the chance to trade a very good RB for one of the most talented RBs the NFL has to offer, you have to believe that I'm going to make that trade every time.
If you're still on the fence, let's put it this way- if Reggie Bush had done exactly what Jones-Drew had done in his first two seasons while splitting time with McAllister, where do you think Bush would be going in initial dynasty drafts right now? Personally, I think he'd be a top-5 pick. Jones-Drew didn't have the hype coming in that Bush did, but in reality, he was a pretty similar prospect, and he has performed like Bush was expected to perform. Think of how excited you were about Reggie Bush in the NFL two years ago. Now apply that to Maurice Jones-Drew.
If nothing else, if Jones-Drew continues sharing the load like this and finishing as a low-end RB1 / high-end RB2, it should prolong his career well beyond what you'd ordinarily expect from a young fantasy-relevant RB, if only because it dramatically decreases his chances of getting a serious injury.