I have said plenty of negative things about the management. I can say it works because they've hit endpoints with statistical significance in both trials. Not primary but that doesn't matter right now. The drug works and I've known it for awhile. Whether it be the peer reviewed papers that confirm its MOA, the anecdotal evidence from all of the eIND use or the trial results--it all adds up and shows that it works. How many people have to die before you're satisfied?
Not sure why anyone would want to be so negative in a pandemic. Does it feel good to be such a pronounced hater with something that could do so much good?
I don't mind dissenting opinions but at least base them on facts instead of the BS that the #shortmafia has invented. Continuously saying both trials failed is patently false. They were poorly designed and yes, didn't hit their primary endpoints but they did hit other secondary endpoints and have provided valuable insight into how the drug works and affirmed Dr. Patterson's hypothesis.
Management is awful but the drug works wonderfully.
It seems like every dissenting opinion is just listening to short mafia. Come on. Here's the PURE FACTS.
THE FDA HAS NOT APPROVED LL BASED ON CD10 and CD12.
You don't have to believe the dissenters, but the FDA has seen all the data and said...no thanks.
Are you telling me? That YOU, Chet, know more about LL efficacy than the regulatory body responsible for regulating drugs and who actually looked at all the data? Come on man. Really?
I work as a registered nurse in a hospital, I have cared for COVID patients....why would I want people to die? I hope the drug works. I used to believe in the drug until...
1) NP lied in a cc about applying for EUA after CD10.
2) It showed no benefit in CD12 original 300+ trial.
Those are two facts. Not short mafia bias. I respect your opinion, but again I just find it annoying that anyone who disagrees with you gets dismissed as short mafia.
Now where we differ is the new subset data. Does it SUGGEST it could benefit critical patients? Yes, but 60 something is much too low to form a definitive answer. I guess you can, since you know more than the FDA, but I won't.
You can buy what NPs selling, but with the effectiveness of the vaccines (8 covid patients at my hospital, 0 in ICU) by the time the NEW trial is done NP or the new CEO will be pimping NASH, Parkinson's, or whatever the next indication is.