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***OFFICIAL CYDY/Leronlimab Thread***


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Does anybody know if when submitted to the FDA the full dataset or findings for each endpoint is made public on the FDA website?

Still mindboggling to me that nobody is picking this up (more doctor buzz, media), unless they are waiting for the full data release to validate findings.

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Yes, go ahead FC42

I closed.  Cydy operation mountain house completed.

Fear is a disease.  Get rid of it or you're doomed for failure.  Though I did hear Leronlimab cures it. This is NOT an investment.  It is a Grand Slam Home Run or a Strike Out gamble in the stock

In these difficult times I look for hope and optimism and found it from Seth on the Yahoo board. Expressed more eloquently than I would be able though you are warned to not to look to Yahoo message boards for guidance. Ironic.

"No other drug can claim they improve NEWS2 clinical markers by 250% compared to the current standard of care. If you examine all of the trial endpoints including primary and secondary, it becomes clear this is by far the most important endpoint to exhibit statistical significance since it is indicative of whether a mild/moderate patient will become severe/critical. Not only is leronlimab the ONLY drug that can claim this through clinical trial results BUT we also are the only drug that can reduce serious adverse events in mild/moderate patients by 64%. Given that there are phase 3 clinical trials as we speak with the primary endpoint being the reductions of SAEs reflects just how important that piece of data is just by itself. Price action does not dictate data or fundamentals and the last thing investors should be doing is looking towards yahoo message boards to help understand the data. Do your own due diligence but weeks ago investors said safety looks good but we need efficacy... well as of this morning we officially have both and in times of unmet medical need, having better safety and efficacy over standard of care warrants emergency use authorization even if the FDA would like a phase 3 for mild/moderate (these are not mutually exclusive events). I’m sure shorts will continue working overtime saying “bad data” and bashing NP but at the end of the day we have statistically significant safety and efficacy data compared to the current standard of care and no amount of bashing, lying, or complaining will change that."

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Guys guys. Come on. Settle down. Tomorrow is the big day with the big news and the big data will be released and it’ll skyrocket!  
 

Tomorrow. Tomorrow. 
I love ya. 
Tomorrow. 
You’re always a day away. 

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3 minutes ago, Otis said:

Guys guys. Come on. Settle down. Tomorrow is the big day with the big news and the big data will be released and it’ll skyrocket!  
 

Tomorrow. Tomorrow. 
I love ya. 
Tomorrow. 
You’re always a day away. 

Definitely not shtick, Otis is scorned.  ;)

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54 minutes ago, djmich said:

Does anybody know if when submitted to the FDA the full dataset or findings for each endpoint is made public on the FDA website?

Still mindboggling to me that nobody is picking this up (more doctor buzz, media), unless they are waiting for the full data release to validate findings.

Per the press release they're going to submit findings and data to FDA "later this week".

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9 minutes ago, Charlie Harper said:

 

Per the press release they're going to submit findings and data to FDA "later this week".

Yep I’m trying to figure out if we get to see it all (what’s submitted) or just only what cydy decides to show

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You guys think being a winner is ####in' easy?  If it was easy everyone would do it.  Every superhero movie's 3rd act contains a moment when all is lost and the hero is left with nothing but despair.  It would be easy to give up.  But you have to have the courage to keep going.  You thinking about selling, or should you hold???  The hardest choices require the strongest will.  We've all been beaten down.  We know what's it's like to lose.  To feel so desperately that we're right yet to fail nonetheless.  But eventually the share price will get back to double digits.  Perfectly balanced, as all things should be.

Lebronlimeade is...inevitable.

Edited by FreeBaGeL
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Put the TV on in the background while making dinner, I Am Legend was on. 
 

So I hear in the background, “...a revolutionary drug to fight cancer, but over 5,000 patients have started showing signs of rabies.” 
 

my first thought was, “That sounds like a Cytodyne Phase 3 press release “

 

:sadbanana:

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I think we were caught up in the sides.  Its not a magic bullet nor a fraud.  So Dr. Yo.  BP have to be scrutinized as does AF and crew.  Like almost everything, the truth lies in the middle.  

Still will always have long cydy shares but it comes down to proof the drug works better than others.  Safe is great, but a placebo is safe though.  That is what the gamble is at this point.

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Even if/when the Covid stuff fails i think their stock still has a floor of around $1.  Cytodyn has a cult like following who won't give up no matter what.  They can always keep the clan believing by doing trials for one of the other 50'ish indications they claim.

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7 minutes ago, Bluto Blutarsky said:

 

“we became aware of some political issues behind the scenes and addressed that with the editor.” 
 

This may be the thread with the most lame excuses of any thread in the forum.  

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8 minutes ago, Dwayne Hoover said:

Patterson is confident his paper will be published soon.  Says its in a final approval stage.  Also said something political got in the way earlier that they will have to deal with behind closed doors.

Does his paper matter to his peers?

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4 minutes ago, greeklightnin said:

Recently, we found that combinations with CCL5/CCR5 antagonist and the anti-PD-L1 antibody inhibited tumor growth and improved overall survival in mice models of PDAC.5Here, we first determined that cancer-FOXP3 mediated immune escape by recruiting regulatory T cells via upregulation of CCL5. We provided the rationale that cancer-FOXP3 could identify PDAC patients suited for combination of ICI and the chemokines/chemokine receptors inhibitor, in order to improve response. Interestingly, CCR5 and CXCR4 serve as the co-receptors for HIV-1 entry into T cells, and they have been used as popular targets for the development of new drugs. BL-8040, the peptide-based motixafortide, exhibits encouraging results in combination treatment. Meanwhile, the CCR5 antagonists, such as the small molecular reagents like maraviroc and the humanized monoclonal anti-CCR5 antibody leronlimab, have achieved the primary endpoints in phase 3 clinical studies on HIV, and therefore could be considered for therapeutic repurposing in PDAC.

In the future, additional studies on incorporating the CCL5/CCR5 and CXCL12/CXCR4 pathway blockade for the treatment of PDAC may overcome the compensation mechanism of single-pathway chemokines/chemokine receptors and encourage the innovation of therapeutic strategies for the lethal disease.

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1 minute ago, Golf Guy 69 said:

I had my daughter break down the test results.  But she probably not experienced enough to matter or post here.

Come on.  Are you not feeling loved?  What did she say?

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4 minutes ago, Dwayne Hoover said:

And they still are, not sure where Golf Guy is coming from.  

Have you completed 2 classes in organic chemistry?  Have you been a CR1 and traveled around the US to sites starting drug studies?  Did you ascend to a CR2 and get on more important drug studies?  Did you become at CR 3 and then the lead on drug studies?  While this happened you were not with one company but different because they were fighting for you to work there?

 

Forget that, you are right.

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3 minutes ago, Golf Guy 69 said:

I will tell you my daughter's professional advice.  Who knows, you might as well ride it out.  But if there was any ground breaking info, I hope she would have told me.  

They haven't given enough data publicly to be truly scrutinized.  

Then ask why.

Say what now?

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15 minutes ago, Golf Guy 69 said:

Have you completed 2 classes in organic chemistry?  Have you been a CR1 and traveled around the US to sites starting drug studies?  Did you ascend to a CR2 and get on more important drug studies?  Did you become at CR 3 and then the lead on drug studies?  While this happened you were not with one company but different because they were fighting for you to work there?

 

Forget that, you are right.

Please read this in the morning after you come back to reality and see if what you are saying makes any sense to yourself.

Its pure jibberish.  My guess is that you think you have strung together a cogent presentation but all you've managed to barely do is string a few unrelated sentences together.

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1 minute ago, Dwayne Hoover said:

Please read this in the morning after you come back to reality and see if what you are saying makes any sense to yourself.

Its pure jibberish.  My guess is that you think you have strung together a cogent presentation but all you've managed to barely do is string a few unrelated sentences together.

After the safety results, she said they had topline study results and they probably weren't significant.  Was that assessment wrong?

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