If I'm understanding the format correctly, the first thing I would do is identify which teams you think are going to be eliminated in the WC games and determine whether their studs will be worth it to play in a loss. Look for garbage time WRs/QBs or high volume RBs. Guys like Flacco, Amari Cooper, Etienne, Kyren Williams.
Then do the same for teams you only expect to play in two games. Start them the next week.
As far as studs on teams I expect to go far, I'd play them as soon as possible too wherever you can. For example, I would expect the 49ers studs to fare better against weaker divisional opponents than whoever they play in the superbowl.
A strategy like this where you frontload studs earlier in the playoffs against weaker opponents sounds good to me at first glance, but its an interesting format.
ETA: If it's H2H, this may not be a good strategy.