This is a bit of a trap game to me. In the CMC thread, I saw a couple "they can beat the Titans without him, let him rest" and I'm not sure I agree with that. I think CMC is needed in this one, especially as the Titans are really bad against RBs out of the backfield. Fannin's big week last week notwithstanding, the Titans have mostly been solid against TEs, this probably isn't a huge Kittle week unless its one of his random multi-TD games. I hope so, as I started Kittle over Pitts, but I think it sets up better for CMC. Let's see if Purdy looks better coming out if the bye, strictly as a passer, Purdy has been worse than Mac Jones was.
The Titans have been more competitive since Callahan was fired. They just whopped what is supposed to be a top-5 Browns defense. I wouldn't take them too lightly. Having said that. I also wouldn't want to be starting any Titans in the fantasy playoffs. I wouldn't be shocked if Pollard had another solid game though against a depleted D, and if Ward can keep the negative plays in check, this will be close.
49ers-24
Titans-21