I'm in the minority, but I don't think that Brissett has been better than Kyler. I think he's been better for McBride/Harrison, but he's also hurt the run game and been turnover prone. SF gets Huff back, and Arizona is down Jonah Williams and Marvin Harrison. I think even with all the guys on IR, SF's D steps up in this one. McBride will get his, though you'd think SF would bracket him and make ANYONE else beat him, but who knows. In theory, he could have 10+ catches, but if Saleh is smart, he's seeing 2 guys every play, and you are inviting the Cards to run.
For SF, Brock Purdy is back, but I'd actually argue the bigger return might be Ricky Pearsall. I think Arizona sells out to stop CMC (good luck) and tries to make the returning Purdy beat them. I wonder if the deep ball ability Pearsall brings takes some pressure off others, especially Kittle, and maybe someone else (Bourne, their best zone WR?) and SF looks like a different (better) offense down the stretch.
49ers-31
Cards-17