Well, lots of different strategies for lots of different drafts.Assuming it's a straight serpentine draft...there is no set time to take a closer. The easiest strategy is to take hitters early and often. What I like to do is zig when everyone else is zagging. Don't be on the end of a run at a position. Either be at the beginning, or not part of it at all. For instance, closers. LEt's say around the 3rd round closers start going. Then it seems like they are flying off the shelf and it doesn't even look like you are going to get a guy guaranteed a job, well, just wait till later to get a closer. There will be guys still around. Or let's say it's the 4th round and now no one has a closer. You've locked up 3 stud hitters, and there are no stud SP's available, well, hell maybe there you START the closer run by grabbing the #1 guy. Then you can wait till much later in the draft to get another one or two, because you have 40 saves in the bank.Each draft really takes a life of it's own. That's the beauty of a baseball draft. No two are even close to alike. Assess your team at all levels along the way. Don't reach.As far as in season moves, again, it all depends on your team relative to your league. If you're great in steals, runs and average but lacking in hr's, you may want to swap out a light hitting julio lugo and plop in a thumper like bobby crosby for awhile. I mean there is no magic wand for this kind of stuff. You need to realistically assess your team against your league each week of the year to see where to make the right moves.