"The prognosis right now doesn't look very good," coach Scott Linehan said afterward. "We'll get an MRI and check it (Monday)."
According to team sources, it is a season-ending injury. McCollum wasn't available to comment after the game, but he was wearing a large brace on his leg.
"That's tough on Andy," left guard Richie Incognito said. "He's going to be sorely missed. We love Andy. Andy and Adam (Timmerman) are really what holds this O-line together. But there's not going to be any dropoff with Larry Turner."