Here are my best guesses for the Lions' pick at #2 overall, with my estimate as to their likelihood of being selected:
27% - OT Joe Thomas (the safest pick for Millen to make, IMO, though not an especially flashy pick)
23% - DE Gaines Adams (the only defensive player they'll consider taking with their first pick, but he'll receive strong consideration)
16% - QB Brady Quinn (what can I say? Either they're considering drafting a QB early, or they're not)
14% - QB JaMarcus Russell (I would rank Russell ahead of Quinn, but I believe there's a good chance the Raiders will take him at #1 if he chooses to enter the draft)
06% - WR Calvin Johnson (I'd actually like to see Millen make this pick, just for the firestorm of protest he'd face from the Lions fans and media. Oh, and CJ's pretty good, too)
05% - RB Adrian Peterson (depending on what they know in April regarding KJ's injury and recovery timetable)
05% - Trade Down and draft someone else, or draft one of these players who might slide down
04% - Draft Someone Else without trading down