(For the house, not for Stealthycat. Cross-posted from another board)
Regarding the mRNA vaccine ingredients, we actually do know exactly what they do both short- and long-term. And we don't have to wait years to find out.
Why? The biological dispensation of all the individual ingredients of the mRNA are already understood. There's no biological pathway for them to have long-term effects -- your cells either use the ingredients for fuel (e.g. lipids, sucrose) or they get excreted (acetic acid, sodium acetate).
For the sake of an example, let's go through the Moderna vaccine ingredients (
from this article, my words italicized) :
mRNA – Also known as messenger ribonucleic acid, mRNA is the only active ingredient in the vaccine. The mRNA molecules contain the genetic material that provide instructions for our body on how to make a viral protein that triggers an immune response within our bodies ... It’s critical to note that the mRNA vaccines never enter the nucleus of the cell, where our DNA is stored. After injection, the mRNA from the vaccine is released into the cytoplasm of the cells. Once the viral protein is made and on the surface of the cell, mRNA is broken down and the body permanently gets rid of it.
Four different lipids – biomolecules that don't dissolve in water, such as fats and sterols (also beeswax). I didn't look these up individually, but if you've ever eaten cheese or cooked with vegetable oil or used bacon, eaten jelly beans, etc. ... you've ingested plenty of different types of lipids.
-SM-102
- 1,2-dimyristoyl-rac-glycero3-methoxypolyethylene glycol-2000 [PEG2000-DMG]
- cholesterol (this one is familiar)
- 1,2-distearoyl-snglycero-3-phosphocholine [DSPC]
The remaining ingredients (below), including acids, acid stabilizers, salt and sugar all work together to maintain the stability of the vaccine after it’s produced.
Acid
Acetic acid - when watered down, this is white vinegar
Acid Stabilizers
Tromethamine & Tromethamine hydrochloride - antacids, but pricey ones that wouldn't be practical to use in over-the-counter medications like Tums (calcium carbonate is practically free). Same function, though.
Salt
Sodium acetate - this is used as an artificial flavoring in, for example, potato chips. Tastes vinegary.
Sugar
Sucrose - regular ol' table sugar.