Depends a lot on scoring and lineup requirements. If PPR, then I love the slot and take one of CJ, MJD, AP, Rice, Gore, and Andre Johnson. If nonPPR, then assuming the first five picks are RBs, I'd take either AJ, Turner or Deangelo all over SJax I think. Not a bad spot to pick from, especially if you're high on any of those guys. In round 2, I'd grab one of the top 2 QBs if available (Rodgers, Brees), or (assuming nonPPR) Shonn Green, Benson, or Grant all are great picks there. I'd go BPA in the 3rd, hoping to land a Colston/Rice/Jennings/Marshall WR. I also like the WR talent on the board in the 4th, assuming you can get a Boldin/Desean Jackson type or one of the above guys who is slipping. My general QB strategy would be to either get one of the top 2 in round 2, or one of the top 7 if one falls into rounds 4 or 5 (Rivers, Schaub could be there in the 5th). If you miss out on one of the top 7, I'd wait until the 9th-10th and get something like a Favre/Cutler combo and play matchups every week.