Its sure sounding like Kyler Murray is a true gametime decision. I know the joke is Kyler sometimes sucks, but he'd still be a huge loss for a team that can't really run and has an average at best defense. I think if he's out (and maybe even if he plays) the Cardinals are gonna have a hard time moving the ball. McBride is still an autostart, though more as a floor play, but Harrison is iffy, and that's all I'd really want to start.
On the flip side, nothing about this Colts offense is fluky other than it being Daniel Jones. Which maybe we have to just get over ala Darnold last year, though Jones probably isn't as big a surprise as Darnold was. Will Johnson has looked every bit like the player he was at Michigan. He's been arguably the best defensive rookie in the NFL this season, and I would imagine he sees the majority of Pittman routes. Colts are getting Alec Pierce back, and Cards are vulnerable deep, I wouldn't be shocked if he got his semi-weekly 40-yard catch. Cards run D is hit/miss, they may slow Taylor a little more than some other teams, but he'll get his for sure. Tyler Warren is the really interesting name to me. He's just missed a couple endzone balls, but he's getting an even bigger rapport with Jones by the week. He's got the best matchup this week, and I expect him to capitalize on it. He's my TE1 this week.
I think the Colts easily cover regardless of Kyler's status,