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Function Health - Expanded Blood Work Testing (1 Viewer)

Joe Bryant

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Staff member
We've talked a little about the sites like Function Health that do expanded bloodwork testing. As I understand it, it's essentially like the blood work you get from your normal doctor, just expanded to cover more things.

It's been on my radar as they're doing a big sale that ends today. www.functionhealth.com

I'm assuming there's a good bit of negativity toward this, but wanted to ask if people might elaborate or if they'd used it and what was their experience.
 
I'll bet there are a few metric tons of psychology rolled up in to their business model. If they get you at $500 (or $365) for bloodwork, they're probably stamping a cash cow icon on your database record, and their brightest people are hard at work on your upsells.

And God help the hypochondriac that signs up for this, and their doctor. ...end cynicism

Also, I think the number of people who will pay $500 for this bloodwork is pretty small, and once that market is tapped, they'll drop the price (at first disgugised as a sale).
 
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I think the thing I'd be interested in is how it differs from the normal bloodwork one gets on a normal physical.

It's my understanding it's like that but with more things they look to.

I guess the question then becomes more, "How many tests are the right number?"

I mean on one end, a physical might be only listen to your heart, look in your eyes, ears and throat and that's it. A normal one today seems to be all that plus blood work that gives quite a few tests from cholesteral to liver enzymes and other things. This Function Health seems to be all that plus more.

So it feels like "where is the line on what's the right amount of information to have?" is the question. But maybe I'm missing it.
 
For what it's worth, I have a friend that's made a pretty dramatic improvement in her health in the last couple of years primariy from diet. Moving to avoid all ultra processed food and getting better sleep and exercise and eating much more healthily. It's made a big improvement in her life. She's been a fan of Function Health and mentioned it today. I'm not sure what exactly it is she loves about it in detail. She said it just helped her feel like she had a better understanding of her health and was able to see objective changes in measuring things she believes is related to her moving to a more healthy lifestyle.
 
I think the thing I'd be interested in is how it differs from the normal bloodwork one gets on a normal physical.

It's my understanding it's like that but with more things they look to.

I guess the question then becomes more, "How many tests are the right number?"

I mean on one end, a physical might be only listen to your heart, look in your eyes, ears and throat and that's it. A normal one today seems to be all that plus blood work that gives quite a few tests from cholesteral to liver enzymes and other things. This Function Health seems to be all that plus more.

So it feels like "where is the line on what's the right amount of information to have?" is the question. But maybe I'm missing it.
your doctor can request "more" tests outside the standard check-up....

I get a couple other tests based on history
 
Also, I think the number of people who will pay $500 for this bloodwork is pretty small, and once that market is tapped, they'll drop the price (at first disgugised as a sale).

I wonder too about how big that market it. On hand, people seem to spend a lot on "health". I have no idea how many customers they have.
 
If I'm remembering right, the primary objection was creating unneccesary worry from the test results or tests that weren't deemed necessary?
It’s more than that.

Some of the tests have no defined clinical utility, meaning, no applicability to health/disease, other than just “knowing”. The results may not be standardized, and the labs who perform them might not follow recommended processing protocols. Plus, every test has an error rate, so the more testing you do, the more likely you’ll find something abnormal, by chance alone. With shotgun testing, it’s easy to get to a point where the rate of false positives exceeds legitimately abnormal findings. Bayes’ theorem tells us this is a bad idea, mathematically at least.

Overall, it results in wasted time and money, at the minimum. More importantly, this sort of diagnostic “fishing” is bound to find something, eventually. Then downstream testing occurs, which may include things like radiation exposure or invasive procedures, all of which have associated risk, and compound unnecessary resource utilization.

I understand we’re in an age where technology allows people to monitor dozens of variables instantaneously, and many believe more data points can only help to individualize decisions about health. But there is a threshold where less is more, when the noise drowns out evidence-based, appropriate clinical care.

Until peer-reviewed data actually proves utility to “holistic” testing protocols, I’d approach it with skepticism, especially when the people advocating the tests benefit financially.
 
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For what it's worth, I have a friend that's made a pretty dramatic improvement in her health in the last couple of years primariy from diet. Moving to avoid all ultra processed food and getting better sleep and exercise and eating much more healthily. It's made a big improvement in her life. She's been a fan of Function Health and mentioned it today. I'm not sure what exactly it is she loves about it in detail. She said it just helped her feel like she had a better understanding of her health and was able to see objective changes in measuring things she believes is related to her moving to a more healthy lifestyle.
I don’t think healthy diet, regular exercise and better sleep fall outside the purview of conventional medicine.
 
Also, I think the number of people who will pay $500 for this bloodwork is pretty small, and once that market is tapped, they'll drop the price (at first disgugised as a sale).

I wonder too about how big that market it. On hand, people seem to spend a lot on "health". I have no idea how many customers they have.
Look no further than the multibillion dollar supplement industry. People are desperate for an alternative to conventional medicine, and willing to spend plenty of money to try something new.
 
If I'm remembering right, the primary objection was creating unneccesary worry from the test results or tests that weren't deemed necessary?
It’s more than that.

Some of the tests have no defined clinical utility, meaning, no applicability to health/disease, other than just “knowing”. The results may not be standardized, and the labs who perform them might not follow recommended processing protocols. Plus, every test has an error rate, so the more testing you do, the more likely you’ll find something abnormal, by chance alone. With shotgun testing, it’s easy to get to a point where the rate of false positives exceeds legitimately abnormal findings. Bayes’ theorem tells us this is a bad idea, mathematically at least.

Overall, it results is wasted time and money, at the minimum. More importantly, this sort of diagnostic “fishing” is bound to find something, eventually. Then downstream testing occurs, which may include things like radiation exposure or invasive procedures, all of which have associated risk, and compound unnecessary resource utilization.

I understand we’re in an age where technology allows people to monitor dozens of variables instantaneously, and many believe more data points can only help to individualize decisions about health. But there is a threshold where less is more, when the noise drowns out evidence-based, appropriate clinical care.

Until peer-reviewed data actually proves utility to “holistic” testing protocols, I’d approach it with skepticism, especially when the people advocating the tests benefit financially.
Love that you mentioned Bayes.
 
Holy carp, I just looked at their battery of tests. A ton of them have no clear utility, and several are ripe for provoking downstream testing. A good example: the multi-cancer detection test.

After reviewing that list, I’ll add anemia to the potential harm caused by this strategy.
 
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If I'm remembering right, the primary objection was creating unneccesary worry from the test results or tests that weren't deemed necessary?
It’s more than that.

Some of the tests have no defined clinical utility, meaning, no applicability to health/disease, other than just “knowing”. The results may not be standardized, and the labs who perform them might not follow recommended processing protocols. Plus, every test has an error rate, so the more testing you do, the more likely you’ll find something abnormal, by chance alone. With shotgun testing, it’s easy to get to a point where the rate of false positives exceeds legitimately abnormal findings. Bayes’ theorem tells us this is a bad idea, mathematically at least.

Overall, it results is wasted time and money, at the minimum. More importantly, this sort of diagnostic “fishing” is bound to find something, eventually. Then downstream testing occurs, which may include things like radiation exposure or invasive procedures, all of which have associated risk, and compound unnecessary resource utilization.

I understand we’re in an age where technology allows people to monitor dozens of variables instantaneously, and many believe more data points can only help to individualize decisions about health. But there is a threshold where less is more, when the noise drowns out evidence-based, appropriate clinical care.

Until peer-reviewed data actually proves utility to “holistic” testing protocols, I’d approach it with skepticism, especially when the people advocating the tests benefit financially.
Love that you mentioned Bayes.
@IvanKaramazov was much more eloquent, when he explained it early in the pandemic. But I'm guessing most functional medicine clients aren’t including conditional probabilities in their decisions.
 
I guess this could be related - my wife and I switched to a concierge MD model years ago even though I work in healthcare and had decent access.

If you have the right MD you can get more frequent lab draws or stuff like advanced lipids etc. it should be a partnership in health not a dictatorship.

Concierge MD : no more waiting rooms for primary and preventive health

Access when you need it

Most RX filled in office.

Private pay - so no insurance or CMS billing or records

If I am in another state on travel and have an allergic reaction he can computer me in a rx to local pharmacy.
 
Ive seen the full list of tests that can be done and the cost of some individual tests are astronomical given the lab work required.
I am surprised rich people dont do this every month.
Bloods are the window of every known malady….allegedly.
But at some stage stressing out about slightly elevated readings can be counterproductive.
Different countries also have different ranges for concern.
 
We've talked a little about the sites like Function Health that do expanded bloodwork testing. As I understand it, it's essentially like the blood work you get from your normal doctor, just expanded to cover more things.

It's been on my radar as they're doing a big sale that ends today. www.functionhealth.com

I'm assuming there's a good bit of negativity toward this, but wanted to ask if people might elaborate or if they'd used it and what was their experience.
I think my biggest questions would be:

a) what actual tests are performed and what is the reasoning behind the test and
b) who evaluates the test results.

If reading test results is a DIY thing, I'm not sure that's particularly meaningful or healthy.
 
Also, I think the number of people who will pay $500 for this bloodwork is pretty small, and once that market is tapped, they'll drop the price (at first disgugised as a sale).

I wonder too about how big that market it. On hand, people seem to spend a lot on "health". I have no idea how many customers they have.
Look no further than the multibillion dollar supplement industry. People are desperate for an alternative to conventional medicine, and willing to spend plenty of money to try something new.
are there any supplements or vitamins that you think are good to add to your daily routine ?
 
We've talked a little about the sites like Function Health that do expanded bloodwork testing. As I understand it, it's essentially like the blood work you get from your normal doctor, just expanded to cover more things.

It's been on my radar as they're doing a big sale that ends today. www.functionhealth.com

I'm assuming there's a good bit of negativity toward this, but wanted to ask if people might elaborate or if they'd used it and what was their experience.
I think my biggest questions would be:

a) what actual tests are performed and what is the reasoning behind the test and
b) who evaluates the test results.

If reading test results is a DIY thing, I'm not sure that's particularly meaningful or healthy.
It's over 16o tests yearly, versus roughly 20 a conventional primary doctor may order (almost all of which aren't evidence-based, nor correlated with improved health, btw).

They have a panel of "experts" to review the results, including celebrity neuroscientist Andrew Huberman.

ETA Their disclaimer makes me think they punt abnormal results to your personal physician, avoiding all liability for the mess they’ve created in the process:
FUNCTION HEALTH DOES NOT OFFER MEDICAL ADVICE, LABORATORY SERVICES, A DIAGNOSIS, MEDICAL TREATMENT, OR ANY FORM OF MEDICAL OPINION, THROUGH OUR SERVICES OR OTHERWISE. FUNCTION HEALTH’S SERVICES ARE NOT A SUBSTITUTE FOR MEDICAL CARE, MEDICAL ADVICE, AND/OR A DETAILED DISCUSSION WITH YOUR PRIMARY CARE PHYSICIAN OR OTHER LICENSED PROVIDER. IF YOU HAVE ANY QUESTIONS REGARDING ANY LABORATORY RESULTS OR OTHER INFORMATION THAT YOU ACCESS THROUGH FUNCTION HEALTH, WE RECOMMEND THAT YOU DISCUSS THOSE QUESTIONS WITH A PRIMARY CARE PHYSICIAN OR OTHER LICENSED PROVIDER. ALL MATERIAL, INFORMATION, DATA, AND CONTENT THAT FUNCTION HEALTH PROVIDES IS STRICTLY FOR GENERAL INFORMATION PURPOSES.
 
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Also, I think the number of people who will pay $500 for this bloodwork is pretty small, and once that market is tapped, they'll drop the price (at first disgugised as a sale).

I wonder too about how big that market it. On hand, people seem to spend a lot on "health". I have no idea how many customers they have.
Look no further than the multibillion dollar supplement industry. People are desperate for an alternative to conventional medicine, and willing to spend plenty of money to try something new.
No money to be made in pharmaceuticals, doctors running a bunch of tests (depending on how good your health insurance is), or hospitals controlling costs, right? It's those supplements where all the money is spent!
 
Also, I think the number of people who will pay $500 for this bloodwork is pretty small, and once that market is tapped, they'll drop the price (at first disgugised as a sale).

I wonder too about how big that market it. On hand, people seem to spend a lot on "health". I have no idea how many customers they have.
Look no further than the multibillion dollar supplement industry. People are desperate for an alternative to conventional medicine, and willing to spend plenty of money to try something new.
are there any supplements or vitamins that you think are good to add to your daily routine ?
With a balanced diet, including adequate fiber intake, the list is short.

Vitamin D for sure, if deficient. Fish oil maybe, but the largest study showing benefit had poor methodology. Calcium if you're at risk for osteoporosis (thin, elderly, female, certain ethnicities).

That's it.

The rest have limited data, at best. I'd guess 80%+ do nothing, 10% cause harm, and the remaining 10% may help, but the science hasn't been done to confirm it. This is a good site to educate yourself a little on what's out there.

FTR, I normally take no supplements, but am consuming extra protein and creatine while I recover from surgery for a torn hamstring.
 
I'd personally lean on a test list derived from Peter Attia's work. You can get them tested at Marek for about half of what this place costs.
 
For what it's worth, I have a friend that's made a pretty dramatic improvement in her health in the last couple of years primariy from diet. Moving to avoid all ultra processed food and getting better sleep and exercise and eating much more healthily. It's made a big improvement in her life. She's been a fan of Function Health and mentioned it today. I'm not sure what exactly it is she loves about it in detail. She said it just helped her feel like she had a better understanding of her health and was able to see objective changes in measuring things she believes is related to her moving to a more healthy lifestyle.
I don’t think healthy diet, regular exercise and better sleep fall outside the purview of conventional medicine.

I don’t think anyone said it doesn’t.
 
For what it's worth, I have a friend that's made a pretty dramatic improvement in her health in the last couple of years primariy from diet. Moving to avoid all ultra processed food and getting better sleep and exercise and eating much more healthily. It's made a big improvement in her life. She's been a fan of Function Health and mentioned it today. I'm not sure what exactly it is she loves about it in detail. She said it just helped her feel like she had a better understanding of her health and was able to see objective changes in measuring things she believes is related to her moving to a more healthy lifestyle.
I don’t think healthy diet, regular exercise and better sleep fall outside the purview of conventional medicine.

I don’t think anyone said it doesn’t.
My point is, tracking a bunch of extra labs likely had nothing to do with her health - lifestyle modifications did. And any conventional provider could have provided those recommendations.

I don’t know for certain, of course, as it’s possible Function’s tests discovered an undiagnosed problem. And having a spreadsheet of data to look at might provide motivation to pursue healthy lifestyle changes, regardless of the actual lab results. Or maybe she just likes access to “experts” like Huberman?

I guess if you're really interested, you could ask what specific tests helped her, and how, then extrapolate if it’s worth it for you.

Alternatively, you could just avoid ultraprocessed foods, increase your activity level, and work on sleep hygiene in earnest. Or ask your doctor what else you can do to optimize health, including the value of some or all of the bloodwork in Function’s panel.
 
Read several pages on that site. I didn't find anywhere it says you talk to a doctor.
You pick your own tests, without a doctor's advice
If you're out of range on something you will get a phone call from a "clinician".
You're encouraged to test as often as you like.
There's no insurance to offset the cost; it's all out of pocket

Live 100 healthy years
Receive a comprehensive summary written by our Clinical Team, who review each biomarker to present a detailed perspective on your health. A clinician will call you promptly if any urgent results arise so you are informed and empowered to act.
Not interested in having my money taken from me like that, which offers worse than what I already have. I get a written report from a lab doctor about all my lab tests. I also get a call from my doctor's nurse explaining the results. And if the results are worrying enough I've gotten a call at home on a Saturday from my doctor. That one surprised me.

But there's plenty of money to be made distrusting doctors, and this site offers "insights" so I imagine they'll do well financially.
 
I understand we’re in an age where technology allows people to monitor dozens of variables instantaneously, and many believe more data points can only help to individualize decisions about health. But there is a threshold where less is more, when the noise drowns out evidence-based, appropriate clinical care.

Hey Terminalxylem, you know I'm generally in agreement with what you say, but "appropriate" is doing a lot of heavy lifting here. "Appropriate," according to Merriam-Webster, means "suitable or fitting," generally for a person or purpose. It can be used in a myriad of different ways by a myriad of different actors, and the question of appropriateness is not an absolute quality.

Nowhere is there an acknowledgement that "appropriate care" is not necessarily synonymous with "best care" or "life-saving procedure at all costs care" because the buzzword of "appropriate" slipped into the language with cost constraints in mind. Somewhere scarcity has to kick in. Whether that is reduced profits for public corporations, or closely-held corporations, or unincorporated insurers; or whether it is less compensation for health care providers and doctors; or whether it is passed on to the insured, or even to the uninsured—in a pie that is fixed, the constraints have to happen somewhere when the demand for services and procedures exceeds the supply of resources and labor or what societal aims are.

So think about "appropriate" and what that means in this context. What is "appropriate" when this happens (the demand exceeding the resources able to be used)? What defines "appropriate"? Is it what we traditionally think—that how we determine what is "appropriate" under our current system is the "best" care for each patient in the doctor/patient relationship—care that is optimal for the patient in each and every instance? Or is there something else in play, especially when what is clearly best for the patient conflicts with the bottom lines of industry and the needs of the rest of society (governance is now implicated also)? How do we then know that "appropriate" could ever mean "unfettered best care for the patient" in those cases, and in our current state of health care services?

I mean, you've written nearly exhaustively about how our system actually isn't good (and stop me if I'm putting words in your mouth) because it's not only wasteful but that patients aren't always best served by how it works.

So a few things, maybe. From what I've noticed in these discussions is that this isn't about a few tests too many that are ordered, or patients "doing their own research" that is the problem, but the underlying tension that our bioethicists, industries, and politicians (and therefore, us as an aggregate) have foisted upon doctors whereby the doctors must balance both public health interests and government interests against the patient's interests instead of what the patient thinks she's getting at the doctor; which is that the doctor treats her as an end unto herself and helps her advocate for herself in myriad ways. I mean, that's what we hope the doctor-patient relationship is, but instead, I've noticed a serious uptick in the amount of discussions regarding public health over the years where the shift from "doctor treats patient" to "doctor balances patient interest against industry and governance interest" has been very, very noticeable.

And patients, no matter how you sugarcoat it, know this. And that inherently breeds massive distrust. Too many (not I) think that doctors are captured by industry and too many think that doctors are captured by political and social concerns and so these people see doctors as providing not a service in the unbridled interest of the patient, but as an arbiter and allocator of scarce resources. They think that the doctor is no longer their "doctor" in a romantic sense, but an adversary in some way.

How do you think we can all go about bridging the gap here?
 
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I've noticed a serious uptick in the amount of discussions regarding public health over the years where the shift from "doctor treats patient" to "doctor balances patient interest against industry and governance interest" has been very, very noticeable.

I've noticed some of the same.
 
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I understand we’re in an age where technology allows people to monitor dozens of variables instantaneously, and many believe more data points can only help to individualize decisions about health. But there is a threshold where less is more, when the noise drowns out evidence-based, appropriate clinical care.

Hey Terminalxylem, you know I'm generally in agreement with what you say, but "appropriate" is doing a lot of heavy lifting here. Nowhere is there an acknowledgement that "appropriate care" is done with cost constraints in mind (wherever that happens along the conveyor belt, from public corporation or closely-held corporation or unincorporated insurer to provider to insured). What you're allowing yourself to say (and I'm not saying you are) is that how we determine what is "appropriate" under our current system is the best care. And you've written nearly exhaustively about how our system actually isn't good.

How do you reconcile the two?
Good point. You are absolutely correct that our system is broken, but it isn’t primarily due to undertesting. If anything, we test way too much. Even with financial constraints, our medical care is the most costly, and wasteful in the world. Outcomes are mediocre, at best.

At the same time, there are instances where insurance lags behind the science, refusing to pay for appropriate testing, procedures, and therapeutics. Usually clinicians can petition to change their minds, and that may entail reviewing contemporary best practice. Or patients hop through hoops for financial assistance. But frank denial of care is pretty uncommon, in my experience (mostly in the hospital setting). Still, it definitely happens, as the cost of care is an inescapable reality.

I’m not sure how any of that justifies paying hundreds-thousands of dollars out of pocket for a bunch of dubious tests. And the people pursuing functional medicine aren't usually the same as those being denied care, typically un- or underinsured people in marginalized communities. I'd bet Function's clients are mostly affluent, college educated, and well insured. They're probably healthier than average, too.

I mean, I get it. People aren't satisfied with Big Medicine, Big Pharma, or any entity that treats healthcare like a business. They want to feel in control of individualized care, and not be a cog in the medical assembly line. I just don't think gratuitous phlebotomy and whole body scans are the answer. Alternative Medicine seems every bit as profit-driven as the other Bigs, even predatory from my vantage point, and much more poorly regulated.

I also think there need to be limits on unnecessary care. Rather than basing it on ability to pay, or recommendations from quasi-medical podcasters, wed to their sponsors, shouldn't doctors do the doctoring?

Clearly, we're failing at preventative care, and that failure is multifactorial, with providers shouldering some of the blame. At the minimum, nutrition, exercise, and functional longevity need to be incorporated into medical curricula, and practitioners prioritize prescribing it. Not sure how that happens, unfortunately. So I guess we're left letting the market decide what patients want, even if it may not be what they need.

ETA I see you edited your post. I agree there's a swath of patients who have grown to distrust doctors, and the institution of medicine. I don't know how we reverse that trend, though an emphasis on informed, shared decision making is a good start. I also think we should learn from what works in other countries, discussion of which treads too far into political territory for this forum.
 
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I understand we’re in an age where technology allows people to monitor dozens of variables instantaneously, and many believe more data points can only help to individualize decisions about health. But there is a threshold where less is more, when the noise drowns out evidence-based, appropriate clinical care.

Hey Terminalxylem, you know I'm generally in agreement with what you say, but "appropriate" is doing a lot of heavy lifting here. Nowhere is there an acknowledgement that "appropriate care" is done with cost constraints in mind (wherever that happens along the conveyor belt, from public corporation or closely-held corporation or unincorporated insurer to provider to insured). What you're allowing yourself to say (and I'm not saying you are) is that how we determine what is "appropriate" under our current system is the best care. And you've written nearly exhaustively about how our system actually isn't good.

How do you reconcile the two?
Good point. You are absolutely correct that our system is broken, but it isn’t primarily due to undertesting. If anything, we test way too much. Even with financial constraints, our medical care is the most costly, and wasteful in the world. Outcomes are mediocre, at best.

At the same time, there are instances where insurance lags behind the science, refusing to pay for appropriate testing, procedures, and therapeutics. Usually clinicians can petition to change their minds, and that may entail reviewing contemporary best practice. Or patients hop through hoops for financial assistance. But frank denial of care is pretty uncommon, in my experience (mostly in the hospital setting). Still, it definitely happens, as the cost of care is an inescapable reality.

I’m not sure how any of that justifies paying hundreds-thousands of dollars out of pocket for a bunch of dubious tests. And the people pursuing functional medicine aren't usually the same as those being denied care, typically un- or underinsured people in marginalized communities. I'd bet Function's clients are mostly affluent, college educated, and well insured. They're probably healthier than average, too.

I mean, I get it. People aren't satisfied with Big Medicine, Big Pharma, or any entity that treats healthcare like a business. They want to feel in control of individualized care, and not be a cog in the medical assembly line. I just don't think gratuitous phlebotomy and whole body scans are the answer. Alternative Medicine seems every bit as profit-driven as the other Bigs, even predatory from my vantage point, and much more poorly regulated.

I also think there need to be limits on unnecessary care. Rather than basing it on ability to pay, or recommendations from quasi-medical podcasters, wed to their sponsors, shouldn't doctors do the doctoring?

Clearly, we're failing at preventative care, and that failure is multifactorial, with providers shouldering some of the blame. At the minimum, nutrition, exercise, and functional longevity need to be incorporated to medical curricula, and practitioners prioritize prescribing it. Not sure how that happens, unfortunately. So I guess we're left letting the market decide what patients want, even if it may not be what they need.

ETA I see you edited your post. I agree there's a swath of patients who have growth to distrust doctors, and the institution of medicine. I don't know how we reverse that trend, though an emphasis on informed, shared decision making is a good start. I also think we should learn from what works in other countries, which treads too far into political territory for this forum.

Oh, I went back and revisited. I didn't think you had seen it or responded, so I edited for a lot of content and clarity. Wow. You must have had this up on the computer earlier. Sorry if that caused any undue issue.

I wasn't really talking so much about the testing in this thread that you and Joe are talking about. You've explained your position about the unnecessary testing a time or two before and just did so in your most recent answer (this one), and frankly, I agree with your positions about both the unnecessary ones and ones not provided that are necessary. I know you get it. You're a bright dude. I also don't really believe in health hacks and stuff that's not backed by peer-reviewed studies and consensus. I just don't. The only time I did was taking a product called Livatone for my liver by one of those dubious and borderline quacks who was selling it. But every ingredient had been rumored to help and some had been proven to, so down the hatch it went (that's the extent of chasing health for me). And I almost chimed in about Stanford because their grad schools and professors and the way they give degrees and who their professors are . . . it's wicked suspect.

So I think we can move on from that. But as I expanded the scope of what I was trying to say, I wound up trying to address what your first thread was really about. I didn't comment there nor at the time, both because I was on hiatus from commenting on social media and also because I felt like both sides had really legitimate things to say to each other. Plus, it was a bit tense. So when considering the patient/doctor relationship and why patients might be feeling a bit adversarial towards "their" doctor I was gently trying to get at the push and pull doctors have to be feeling from the purveyors of (what I think) is the monstrous creep of the "public health" mission and also the creep of regulated industry and governance, which is a huge topic that I'm not an expert in but can reasonably talk about it, only we can't do that here.

What I wanted to say was simply that patients don't feel like their doctors are their doctors anymore and we can hear the discussions going on almost like "above our heads" but those of us with a brain can hear them. And we hear, in big flashing lights, "keep industry lobbies happy with profits and manage government expenditures by rationing care."

And as public health and the scope of it increases, it'll only get worse. And without getting political one can see the problems coming down the pike for the patient and doctor relationship, and I'm not sure radical improvement is feasible or likely.

And that's about it. Just my two cents, really, in a roundabout way. Peace, man. Take care.
 
On a completely different note, patients who elect treatment in functional medicine centers report better health-related quality of life:
Objective To assess the association between functional medicine and patient-reported HRQoL using Patient-Reported Outcome Measurement Information System (PROMIS) global health measures.

Design, Setting, and Participants A retrospective cohort study was performed to compare 7252 patients aged 18 years or older treated in a functional medicine setting with propensity score (PS)–matched patients in a primary care setting. Sensitivity analyses assessed improvement limited to patients seen at both 6 and 12 months. The study included patients who visited the Cleveland Clinic Center for Functional Medicine or a Cleveland Clinic family health center between April 1, 2015, and March 1, 2017.

Main Outcomes and Measures The primary outcome was change in PROMIS Global Physical Health (GPH) at 6 months. Secondary outcomes included PROMIS Global Mental Health (GMH) at 6 months and PROMIS GPH and GMH at 12 months. The PROMIS GPH and GMH scores were transformed to a T-score from 0 to 100 with a mean of 50. Higher scores indicate a better health-related quality of life.

Results Of the 7252 patients (functional medicine center: 1595; family health center: 5657), 4780 (65.9%) were women; mean (SD) age was 54.1 (16.0) years. At 6 months, functional medicine patients exhibited significantly larger improvements in PROMIS GPH T-score points than were seen in patients treated at a family health center (mean [SD] change, functional medicine center: 1.59 [6.29] vs family health center: 0.33 [6.09], P = .004 in 398 PS-matched pairs). At 12 months, functional medicine patients showed improvement similar to that observed at 6 months; however, comparisons with patients seen at the family health center were not significant. Patients in the functional medicine center with data at both 6 and 12 months demonstrated improvements in PROMIS GPH (mean [SD], 2.61 [6.53]) that were significantly larger compared with patients seen at a family health center (mean [SD], 0.25 [6.54]) (P = .02 in 91 PS-matched pairs).

Conclusions and Relevance In this study, the functional medicine model of care demonstrated beneficial and sustainable associations with patient-reported HRQoL. Prospective studies are warranted to confirm these findings.
So if patients can afford it, and feel better, why not try it?

Caveats: Retrospective studies are ripe for confounders, and I know nothing about PROMIS, though it sounds good:
The PROMIS 10 consists of ten (10) items that measure physical health, physical functioning, general mental health, emotional distress, satisfaction with social activities and relationships, ability to carry out usual social activities and roles, pain, fatigue and overall quality of life. It has been tested and validated in younger and older adults (Mariano et al. 2016) and in a wide range of clinical populations (eg. Pearman et al. 2016; Doll et al. 2016; Katzman et al. 2016) and settings (eg. Bryan et al. 2014; Hinami et al. 2015). The ten (10) questions of the PROMIS 10 have largely been adapted from other frequently used legacy measures, such as the SF-36 and EQ-5D and modified for greater sensitivity and precision.

The scoring algorithm allows each of the individual items to be examined separately to provide specific information about perceptions of physical function, pain, fatigue, emotional distress, social health and general perceptions of health. A study from the PROMIS network supported the derivation of two 4-item summary scores: a Global Physical Health (GPH) score and a Global Mental Health (GMH) score. The GPH and GMH score can be used to arrive at a “bottom-line” summary.

The PROMIS 10 scores are predictive of healthcare utilization, mortality in general and disease-specific clinical populations. GPH and GMH scores are scored on a T-Score Metric allowing for comparisons to a general population.
 

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