Really good topic as these guys are in very similar situations as NFL WR2s coming off seasons where they produced like WR1s, so there is a bit of an NFL Perception vs. Fantasy Reality gap.
I was pimping the Nelson Bandwagon pretty big in the Pool early last year so I'm a bit biased

. I was also a Nicks owner so unfortunately got to know Cruz a little more than I'd want to as well.
That said, I'm targeting Cruz. I think he is the better NFL player and unlike GB where there are a ton of mouths to feed, there are only two in NY, and unless Nicks is so hobbled that teams stop doubling him, I think the Giants are fine with their passing system where Nicks gets doubled and Cruz eats up single, with Nicks still able to make the occasional play.
As for Nelson, I'm not a fan of the "yeah, well, take away that one big play" mentality, but with Nelson it seemed like there were more than a couple potential 2/20 games saved by one huge play. I mean, I guess it's great it happened enough where it wasn't really flukey (if that makes sense?) and the guy makes big plays, and it was fine when you were playing the guy essentially as a WR3, but taking him as a WR2 borderline WR1 I'd want more consistency.
Plus, I loved Cobb in college and really think he is a special talent that will start earning his way onto the field more and more.