This is a game between a decent team possibly missing its best player, and a bad team hopefully getting their best player at close to 100%.
For Green Bay, I think their offense is going to really depend on how healthy Aaron Jones truly is. If he's healthy enough for 20+ touches, I suspect they'll be able to move the ball. If not, I don't know their OL can block Donald and co. This feels like a game where Love is gonna have to make a big play or 2, and I'm not confident he can if Jones can't.
For the Rams, Stafford to Rypien is a monumental downgrade and the Rams OL isn't likely to protect him all that well against Gary and co. That said, Kupp and Puka should be wide open all day long, as the Packers secondary is awful, so if they can keep it to 3-5 step drops they could be fine.
I'll say Rams win 21-17.