Others have already mentioned the injuries, but I'll expand on it a little bit.
The Bucs have lost Gerald McCoy, Aqib Talib, Cody Grimm, and Quincy Black over the past 3 weeks. In my opinion, these are 4 of the Bucs 5 best defensive players (Ronde Barber being the other).
Replacing McCoy is Frank Okam (who was just activate from the practice sqaud - and was just signed to the practice sqaud a month ago). The Bucs starters on the d-line will be Tim Crowder, Roy Miller, Frank Okam and Stylez G. White. Michael Bennett will also rotate in on passing downs. I really don't expect much pass rush on Sunday. The Bucs have been blitzing more over the past few weeks, but Quincy Black was the best blitzing linebacker on the team.
The Bucs should get an INT or two on Sunday. If Drew Stanton is starting, there's probably worse options out there, but I would stay away from the Bucs D this week.