Football is a violent game. RB is the most violent position in the game. Guys who can survive the beating over multiple seasons like Edgerrin James, Clinton Portis, and LaDainian Tomlinson are the exception and not the rule (and even those guys have had injury issues). If you play RB, you're going to get hurt.
Despite what fervent Bush haters like TheFanatic say, Reggie's injuries probably have nothing to do with toughness or being soft. If you get hit the wrong way, you're going to get injured. It doesn't matter who you are. Ask Ronnie Brown, Frank Gore, Deuce McAllister, Fred Taylor, Ahman Green, Terrell Davis, Willis McGahee, Cadillac Williams, Jamal Lewis, or any of the innumerable pro backs who have suffered severe injuries in their career.