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A Cure for AIDS? (1 Viewer)

I remember hearing a couple years back about people being immune to HIV because of that deficiency. I'd like to get tested to see if I'm immune too. If so, :football: .

 
In all seriousness, this is one of the most promising articles I have read in years. And it also suggests a key to the cure of all sorts of other diseases, as well. There are always a few people whose genetic structure are naturally immune to any given disease. Could bone marrow transplants also transfer the immunity? Wow.

 
timschochet said:
In all seriousness, this is one of the most promising articles I have read in years. And it also suggests a key to the cure of all sorts of other diseases, as well. There are always a few people whose genetic structure are naturally immune to any given disease. Could bone marrow transplants also transfer the immunity? Wow.
Click to expand...
I saw this on Heroes. The guy may live, but he'll turn into a lizard.
 
timschochet said:
In all seriousness, this is one of the most promising articles I have read in years. And it also suggests a key to the cure of all sorts of other diseases, as well. There are always a few people whose genetic structure are naturally immune to any given disease. Could bone marrow transplants also transfer the immunity? Wow.
Click to expand...
Like in the TV show Heroes, where if you inject the blood of someone with powers into someone without powers, they can manifest their own powers.Except in this case the power is the resistance to certain diseases.
 
Sand said:
Mr Anonymous said:
Thank you Barack Obama!
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:rolleyes: Can we not have this be a political thread?
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But considering the government created AIDS to kill off blacks and gays when the hurricanes weren't sufficient :lmao: , why shouldn't politics enter into the discussion? :lmao:This doctor will likely be found having bled to death after accidentally falling on a broken test tube 37 times.All kidding aside, this is good news. Leukemia research often has spin-off effects. :thumbup:
 
HIV Is Evolving To Be Less Deadly

HIV is rapidly evolving into a less-dangerous bug and could one day become a disease that’s “almost harmless”.

Scientists have observed a surprising increase in the ability of some patients in Africa to live with the virus without getting Aids, the deadly syndrome in which their immune systems collapse.

“If the trend that we’ve seen in the last 10 years in Botswana were to continue – and I see no reason why it shouldn’t – the number of people who can control the virus through their immune system would definitely go up,” said Oxford University immunologist Phillip Goulder.

“It’s not impossible to see HIV becoming less of a cause of disease. And that’s what you see in the monkeys who are naturally infected with SIV [simian Immunodeficiency virus], the relation of HIV, which is where we actually got HIV from. They suffer no disease at all,” he said.

hiv_03_infected1_full

An HIV-infected cell (Credit: Wikimedia)

“But it would be overstating it to say HIV has lost its potency. It’s still a virus you wouldn’t want to have.”

HIV mutates fast, allowing it to evade both the body’s natural defences and those thrown up by modern medicine, thus helping it to spread rapidly, infecting some 80 million people since it emerged in the 1980s, of whom half have died.

However, the central core, containing the viral RNA and crucial enzymes, is less able to evolve quickly.

Changes there in response to threats from the immune system or drugs damage its ability to replicate, according to Professor Goulder and his team, whose results are reported in Proceedings of the National Academy of Sciences.

“HIV adaptation to the most effective immune responses we can make against it comes at a significant cost to its ability to replicate,” Goulder said. “Anything we can do to increase the pressure on HIV in this way may allow scientists to reduce the destructive power of HIV over time.”

Professor Goulder’s team looked at 2,000 female patients in Botswana and South Africa. In Botswana, many of the patients have a gene variant called HLA-B*57 which helps to protect them. The HIV there has learnt to adapt to this, but in the process it has become less virulent.

This is not totally unexpected. Scientists have long believed that most viruses start out deadly, and mellow with age.

Killing the host quickly is a poor tactic for the bug. From the perspective of the virus, it’s better to have hosts live long enough to spread the invader to many others, much the way the common cold virus does.

However, working against this is pressure to reproduce quickly, so that there will be plenty of viral copies available to spread to the next victim during sex.

The scientists also found that treating the sickest patients accelerates mutation of the virus into varieties that reproduce more slowly.

“HIV adaptation to the most effective immune responses we can make against it comes at a significant cost to its ability to replicate,” Professor Goulder said. “Anything we can do to increase the pressure on HIV in this way may allow scientists to reduce the destructive power of HIV over time.”
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Now that they have ebola primed and ready to take over as the depopulation tool they can slowly release the cure they have had all along.

Watch how ebola "mysteriously" mutates to something more effective or some new virus is "discovered". Not airborne, that would just cause panic, but something easily transferable by contact that kills slowly to maximize the time each carrier can spread the infection.

If you open your eyes the pieces all fall in to place.

 
In the United States, HIV is far from the death sentence it was considered 20 years ago. It is however a lifelong disease where a carrier is forced to take strong meds every day to live a long life.

 
cstu said:
HIV Is Evolving To Be Less Deadly

Killing the host quickly is a poor tactic for the bug. From the perspective of the virus, it’s better to have hosts live long enough to spread the invader to many others, much the way the common cold virus does.

However, working against this is pressure to reproduce quickly, so that there will be plenty of viral copies available to spread to the next victim during sex.

The scientists also found that treating the sickest patients accelerates mutation of the virus into varieties that reproduce more slowly.
Click to expand...
Click to expand...
I hate it when they report on "evolution" like this, as if a population decides which traits are advantageous and tries to get better at them. Saying something like "killing the host quickly is a poor tactic for the bug" implies that the "bug" decides what the best tactic is, and decides how quickly it should kill its host.

A better way to say it might be, versions of the bug that kill their hosts too quickly tend to die off because their hosts can't #### in time to spread the disease before they die. But versions that kill their host slower tend to live because their hosts might not even know they have it, so they just keep on #######.

Same thing goes for "treating the sickest patients accelerates mutation of the virus into varieties that reproduce more slowly." That's not really right. What really happens is that versions of the virus that make their patients sicker tend to get the heaviest treatment, which kills them off before they can spread. Versions of the virus that reproduce more slowly tend to get their patients less sick, which means they don't seek treatment to kill off the bug before it can reproduce.

Evolution doesn't happen because the bug wants to reproduce better. It happens because bugs that reproduce better spread their genes more, and bugs that don't, tend to die off before they can spread their genes. Imagine someone reading this article who honestly wonders how, if we evolved from monkeys, there are still monkeys. There's just no way they'd believe any of this stuff is really happening. It would sound like it was totally made up

 
MC Gas Money said:
Now that they have ebola primed and ready to take over as the depopulation tool they can slowly release the cure they have had all along.

Watch how ebola "mysteriously" mutates to something more effective or some new virus is "discovered". Not airborne, that would just cause panic, but something easily transferable by contact that kills slowly to maximize the time each carrier can spread the infection.

If you open your eyes the pieces all fall in to place.
Click to expand...
Only a guy with a 176 IQ would realize what the government is doing here, and only someone with a very large penis would have the guts to reveal it to the rest of us. Thank you, sir!

 
timschochet said:
MC Gas Money said:
Now that they have ebola primed and ready to take over as the depopulation tool they can slowly release the cure they have had all along.

Watch how ebola "mysteriously" mutates to something more effective or some new virus is "discovered". Not airborne, that would just cause panic, but something easily transferable by contact that kills slowly to maximize the time each carrier can spread the infection.

If you open your eyes the pieces all fall in to place.
Click to expand...
Only a guy with a 176 IQ would realize what the government is doing here, and only someone with a very large penis would have the guts to reveal it to the rest of us. Thank you, sir!
Click to expand...
Preach it brother!

 
bostonfred said:
cstu said:
HIV Is Evolving To Be Less Deadly

Killing the host quickly is a poor tactic for the bug. From the perspective of the virus, it’s better to have hosts live long enough to spread the invader to many others, much the way the common cold virus does.

However, working against this is pressure to reproduce quickly, so that there will be plenty of viral copies available to spread to the next victim during sex.

The scientists also found that treating the sickest patients accelerates mutation of the virus into varieties that reproduce more slowly.
Click to expand...
Click to expand...
I hate it when they report on "evolution" like this, as if a population decides which traits are advantageous and tries to get better at them. Saying something like "killing the host quickly is a poor tactic for the bug" implies that the "bug" decides what the best tactic is, and decides how quickly it should kill its host.

A better way to say it might be, versions of the bug that kill their hosts too quickly tend to die off because their hosts can't #### in time to spread the disease before they die. But versions that kill their host slower tend to live because their hosts might not even know they have it, so they just keep on #######.

Same thing goes for "treating the sickest patients accelerates mutation of the virus into varieties that reproduce more slowly." That's not really right. What really happens is that versions of the virus that make their patients sicker tend to get the heaviest treatment, which kills them off before they can spread. Versions of the virus that reproduce more slowly tend to get their patients less sick, which means they don't seek treatment to kill off the bug before it can reproduce.

Evolution doesn't happen because the bug wants to reproduce better. It happens because bugs that reproduce better spread their genes more, and bugs that don't, tend to die off before they can spread their genes. Imagine someone reading this article who honestly wonders how, if we evolved from monkeys, there are still monkeys. There's just no way they'd believe any of this stuff is really happening. It would sound like it was totally made up
Click to expand...
I know what you're saying but scientists take for granted that people understand what you described.

 
MSNBC will be praising Hillary for her work against the AIDS virus in preparation for her campaign. Tingles will be felt throughout the newsroom.

 
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