Avoid Big-10 RBs. Avoid Florida WRs. Not much has changed.
like Percy Harvin and Louis Murphy.
No, more like the Travis Taylors, Gaffneys, Caldwells(both of 'em), Jacobses, Bakers, Chad Jacksons, etc. etc. And that's just from the 2000's. Doesn't even stretch back to the Spurrier heyday of the Jack Jacksons, Reidel Anthonys, Willie Jacksons, Doerings, McGriffs, Millses, Hilliards, et al. Jacquez Green, anyone?
Hell, after going down memory lane there, it appears it would probably be better to say 'avoid Steve Spurrier wideouts' than it would be to say 'avoid Fill In The College Here' wideouts. Most of the Florida busts at the position came on Steve's watch.
Over the past couple decades the university of Florida has had, from what I can remember, precisely one long-term, 'impact' fantasy WR: Darrell Jackson....who was drafted 10 years prior to either Harvin or Murphy (And he was believed to be a pretty big shot in the dark when he was drafted, coming off a big junior season that most pundits credited almost completely to the fact that teams rolled coverage to Travis Taylor/due to Taylor missing games with an ankle that year). That's a pretty big drought for a school that regularly throws the ball as much as the Gators did(and still do) in that time period. Maybe Harvin and/or Murphy break that cycle. Maybe.
Avoiding UF wideouts seems to probably have been a pretty safe play most seasons for the past good little while.
tldr verision: Greetings, Mr. Squirrel. You may have found a couple nuts if those two pan out.