Which Carmine's?  My family would love it, and they can eat.  Theater district location showing no availability from 6-10 any day we are there in June on open table.  Really?  Is this location the best or the one on 91st? We are staying at Doubletree suites Times Square.
Not looking at high end restaurants - how many reservations in advance should I be making?
		
		
	 
Big, big (as in it couldn't be bigger) 
X on Carmines.It's basically dogfood with a ton of garlic dished out banquet-style for birthday parties and office parties on the cheap. There are SOOOOOOOOOO many places to eat in NYC that it is borderline disgraceful that somebody would actually choose to eat there. Only redeeming quality of the place is that you can go there with a group of 10+ and get a table. Central Park also fits that criteria, minus the garlic/bad-Italian-food overload.
Other than Esca (which is more upscale and $$ and definitely needs reservations), I can't think off-hand of Italian places in the theater district I'd recommend. But for theater dining, I've never had a problem with Ruby Fu's (pan-Asian) or any of a myriad of newish places on 9th Ave. Bobby Layne will be your man for that hood.