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*** OFFICIAL *** COVID-19 CoronaVirus Thread. Fresh epidemic fears as child pneumonia cases surge in Europe after China outbreak. NOW in USA (1 Viewer)

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I still mask in public places and in my business office, not out of concern for myself but out of concern for others. I realize I can still get COVID and I don't wish to pass it to others; masking lessens the chance that I do. To me that's a no-brainer, wearing a mask to protect others. It's a piece of cloth, like a necktie or underpants. Other people matter
This, so much this. I still wear a mask too.

 
North Dakota is ranked #24, basically at the US avg for deaths per unit of population.  South Dakota is ranked #14 (which isn’t good) with 10% higher deaths per unit of population than the US avg.

https://www.worldometers.info/coronavirus/country/us/

It’s beyond disappointing and sad that we are still seeing 1000-1500 people die per day in the US.   This didn’t have to happen at this stage.  We’re having another 9/11 every 2-3 days.  Wtf is wrong with us as a people?
Cases, not deaths. The Dakotas and Wyoming are 3 of the top 5, and Utah, Montana and Idaho aren’t far behind.

Death rate patterns are a bit more unpredictable, but roughly correspond to the places whose healthcare systems were most overwhelmed + those with greater percentage of high risk individuals (possibly underserved populations too?).

 
I mean Adams' #1 reason for winning the primary and the election was because hes an ex-cop that will be tough against crime and finally clean up this city. Or did you ignore the last 8 years.
I mean what does this have to do with police supposedly leaving because of vaccination status

 
jobarules said:
3Q21 was the worst quarter for life insurance carriers in a LONG time. Not many of us can figure out why. Its not all COVID related. One theory is the lockdowns in 2020 and people not visiting the doctors are catching up with us. Another theory is that coroners in the Southern states were hiding deaths in 2020 for political reasons. Vehicular accident deaths are the highest they have been in years. Crazy stuff.
Probably multifactorial, with underestimated COVID deaths, late COVID complications and deferred medical care. I also had heard about MVAs being up. I expect stuff related to drug and alcohol abuse as well. Interestingly, suicides we’re down the last I looked.

 
BigJim® said:
:goodposting:

Just got results, I do have breakthrough virus. I have a dr appt in a couple hours. One topic to be discussed is monoclonal. Can anyone offer suggestions? I consider myself in good shape, but a lot of muscle mass probably approaches the BMI threshold. If my symptoms are improved today do I just wait it out or is this the sort of treatment there's no harm in doing if available? 
It’s only recommended for people with high risk of COVID complications. 

 
Question: Why is the flu vaccine not mandated for children when it is proven to be more dangerous to children than COVID? My pediatrician told us this as well. I understand the Covid shot is not mandated for children yet but its only a matter of time.

 
Question: Why is the flu vaccine not mandated for children when it is proven to be more dangerous to children than COVID? My pediatrician told us this as well. I understand the Covid shot is not mandated for children yet but its only a matter of time.
It isn't yet, but may be in the future

To answer your question as to why not yet, my guess would be partly due to needing it annually and partly due to the fact that it is only partially effective (and variable from year to year).  In that sense, it's very different from other vaccines that are mandated. 

But, for example, health care workers are mandated to get it every year.  And, with Covid around and seeing how things were last year without really any flu (very very small number of cases), I wouldn't be surprised to see this get push soon.  As it is, flu shots are offered much more readily with any kind of health encounter to get the number of kids vaccinated for influenza up.

 
It’s only recommended for people with high risk of COVID complications. 
It's basically what my Dr said - though adding that >70% of Americans fit a criteria for risk (as do I with a 25 BMI). He did not frame it as not "recommended" for others, but rather that criteria are being used due to limited supply. Said it's been extremely effective avoiding downturns after feeling better, and said I should do it if I wanted to drastically reduce that risk. My current mindset is "why the heck not?" so would be interested whether you disagree with what I heard.

 
On March 24, 2020, the state of Louisiana first reported on hospitalizations from COVID-19, announcing that 271 people in the state were hospitalized with the virus.

Today, the state reported the lowest number of patients in hospitals since the pandemic began with 235 hospitalized.  

Previous low was 242 back in June 2021.

 
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My wife got shot #2 about a week or so back, and the injection spot is still badly bruised.  She went back to the Target-CVS pharmacy to have them look at it, and they said it wasn't anything to worry about.  We were especially concerned since we just scheduled our two kids (10 and almost 9) to get their first jabs at that same location.  So hopefully these pharmacists know what the heck they're doing 'cuz I don't want my kids to have any complications!  

My wife was skeptical on getting them vaccinated but we're going ahead with it.  Like with other vaccines, though, we are not going to rush into getting them the 2nd shot.  We'll get them the 2nd shot and ultimately the booster, but we prefer to spread things out a bit to give their bodies a chance to get used to whatever's now in their bodies.

 
It's basically what my Dr said - though adding that >70% of Americans fit a criteria for risk (as do I with a 25 BMI). He did not frame it as not "recommended" for others, but rather that criteria are being used due to limited supply. Said it's been extremely effective avoiding downturns after feeling better, and said I should do it if I wanted to drastically reduce that risk. My current mindset is "why the heck not?" so would be interested whether you disagree with what I heard.
My personal opinion: it depends on several factors.

1. Age. If you’re over age 50-55, I’d do it. There’s a single study which shows benefit for people age 55 or greater, regardless of comorbidities. Here’s a good summary of comorbidity data

2. An honest assessment of your BMI. If you’re truly just at the cut-off for overweight, and don’t have excess body fat, I wouldn’t receive the treatment on a technicality. Disclaimer: In my experience, the vast majority of people who dismiss BMI because of “extra muscle” are incorrect about their body composition. BMI underestimates adiposity more often than overestimates it. Here’s data on BMI and covid risk. Figure 1 is especially helpful

3. Duration of symptoms. The studies for monoclonal antibodies showed benefit if given early, typically 3-5 days after symptom onset/diagnosis. Here’s that data

All that being said, the risk associated with receiving the antibodies is low. But in a vacuum, your risk for disease progression as a breakthrough case is also low. And if treatment availability is limited in your area, you may be preventing someone else from getting it. Statement on prioritizing antibody treatment

So you can listen to your doctor, or some Holiday Inn healthcare worker who doesn’t know all those details and your full medical history. The safest bet is following your doctor’s advice, which I assume you trust.

 
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It's basically what my Dr said - though adding that >70% of Americans fit a criteria for risk (as do I with a 25 BMI). He did not frame it as not "recommended" for others, but rather that criteria are being used due to limited supply. Said it's been extremely effective avoiding downturns after feeling better, and said I should do it if I wanted to drastically reduce that risk. My current mindset is "why the heck not?" so would be interested whether you disagree with what I heard.
Didn't address this part of your post. AFAIK, the monoclonal antibodies haven't been studied in younger people without conditions posing higher risk for covid complications. While they're unlikely to be harmful, it's also possible they provide negligible benefit, especially in breakthrough cases.

 
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My wife got shot #2 about a week or so back, and the injection spot is still badly bruised.  She went back to the Target-CVS pharmacy to have them look at it, and they said it wasn't anything to worry about.
Really need @Terminalxylem , @gianmarco or @Biff84 to weigh in, but my understanding is that a bad bruise after any injection is kind of a luck-of-the-draw thing (no pun intended). If her shot had been given a millimeter away from where it actually went in, she likely wouldn't have bruised at all. Am I reading between the lines correctly to say that your wife didn't bruise after her first shot?

 
Really need @Terminalxylem , @gianmarco or @Biff84 to weigh in, but my understanding is that a bad bruise after any injection is kind of a luck-of-the-draw thing (no pun intended). If her shot had been given a millimeter away from where it actually went in, she likely wouldn't have bruised at all. Am I reading between the lines correctly to say that your wife didn't bruise after her first shot?
Yes, or improper technique. 

Unless the bruise is getting bigger (representing ongoing bleeding) or she’s bleeding/bruising elsewhere (indicating a systemic bleeding/clotting problem), I wouldn’t worry about it. 

 
North Dakota is ranked #24, basically at the US avg for deaths per unit of population.  South Dakota is ranked #14 (which isn’t good) with 10% higher deaths per unit of population than the US avg.

https://www.worldometers.info/coronavirus/country/us/

It’s beyond disappointing and sad that we are still seeing 1000-1500 people die per day in the US.   This didn’t have to happen at this stage.  We’re having another 9/11 every 2-3 days.  Wtf is wrong with us as a people?


Apparently we just need to get back to normal :shrug:

 
Nov 5 (Reuters) - A trial of Pfizer Inc's (PFE.N) experimental antiviral pill for COVID-19 was stopped early after the drug was shown to cut by 89% the chances of hospitalization or death for adults at risk of developing severe disease, the company said on Friday.
https://www.reuters.com/business/healthcare-pharmaceuticals/pfizer-says-antiviral-pill-cuts-risk-severe-covid-19-by-89-2021-11-05/

Good news, obviously.  Also another potential off-ramp for folks who missed the last one.

 
Still a way to go, but getting such unequivocal results from an actual trial is super positive.  And having a vax up front + effective treatment on the breakthroughs would make COVID trivial for most people.  Haven't actually done any math stuff, but I'd bet it really would make it less dangerous than the flu.

 
This is an interesting study which may hint at the limits of natural (and by extension, vaccine-induced) immunity to SARS-CoV-2. They looked at reinfection rates with non-SARS coronaviruses over an 8 year period:

Results

Of 3418 participants, 40% were followed for ≥3 years. A total of 1004 HCoV infections were documented; 303 (30%) were reinfections of any HCoV type. The number of HCoV infections ranged from 1 to 13 per individual. The mean time to reinfection with the same type was estimated at 983 days for 229E, 578 days for HKU1, 615 days for OC43, and 711 days for NL63. Binding antibody levels to seasonal HCoVs were high, with little increase postinfection, and were maintained over time. Homologous, preinfection antibody levels did not significantly correlate with odds of infection, and there was little cross-response to SARS-CoV-2 proteins.

Conclusions

Reinfection with seasonal HCoVs is frequent. Binding anti-spike protein antibodies do not correlate with protection from seasonal HCoV infection.
I’m sure the antivaxx are going to latch on to the conclusion’s last sentence. But we already know vaccines and prior infection with SARS-CoV-2 lessen the risk of subsequent infection, and certainly severe disease.

Even though reinfection rate was 30% for any coronavirus type, it looks like a second infection with the same type was delayed well over a year and a half, on average, and much longer for certain strains. It’s also interesting that preinfection antibody levels didn’t correlate with reinfection risk.

In any event, data like this may help in guesstimating covid vaccine booster intervals.

ETA also a bummer antibodies to the regular coronaviruses don’t seem to cross react with SARS-CoV-2, as I know people have speculated they might help in staving off covid.

 
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In Greece there are vaccination clinics, and vaccination requirements for certain jobs and venues, with testing requirements for people who aren't vaxxed. Antivaxxers have been bribing doctors and nurses to inject them with water instead of the vax itself and to show them as vaccinated, in order to skirt requirements.

And some doctors and nurses are pocketing the money, and injecting them with the vaccination instead of water anyway. 

I have a hard time picturing a doctor or nurse getting in any trouble over this. "Your honor, this doctor defrauded me by vaccinating me at a vaccination clinic." :D

 
In Greece there are vaccination clinics, and vaccination requirements for certain jobs and venues, with testing requirements for people who aren't vaxxed. Antivaxxers have been bribing doctors and nurses to inject them with water instead of the vax itself and to show them as vaccinated, in order to skirt requirements.

And some doctors and nurses are pocketing the money, and injecting them with the vaccination instead of water anyway. 

I have a hard time picturing a doctor or nurse getting in any trouble over this. "Your honor, this doctor defrauded me by vaccinating me at a vaccination clinic." :D
Slightly similar, have had a few offers. One offered $500 for a filled out vaccine card. Told him I’d give him the shot for $40 paid by his insurance company. A couple months later he did get it. Twice was offered a bribe to say that I gave the shot without giving it. One of the times is was after I gave the shot and she didn’t even notice. I don’t know how serious the offers were but obviously didn’t consider them.

 
Really need @Terminalxylem , @gianmarco or @Biff84 to weigh in, but my understanding is that a bad bruise after any injection is kind of a luck-of-the-draw thing (no pun intended). If her shot had been given a millimeter away from where it actually went in, she likely wouldn't have bruised at all. Am I reading between the lines correctly to say that your wife didn't bruise after her first shot?
More than likely bad luck but it also could have been poor technique or poor supplies. We get a box of supplies with each vaccine order and they are typically full of crap supplies that we never use. They could have used some of those bad supplies to use them up or by accident.

I’ve done so many shots in the last year that it’s become second nature. I have a process down that works great and most people barely feel the shot. But every once in awhile I choose the wrong spot and it’s an extra painful shot.

 
I had my second dose of the Pfizer vaccine yesterday. Started with muscle aches (low back, neck, and butt) last night. Today had a headache as well as continued aches. Felt crummy enough to take a 2 hour nap in the early afternoon. Woke up and all symptoms gone.
Took my Pfizer booster on Monday. Felt similar body aches the day after, but no headache. Was able to work (did take some acetaminophen).  However, I did have swollen and tender lymph nodes in my armpit on the booster side, first noticed about 24 hours after the booster and lasted until Friday. That was new.

FWIW, I got boosted at CVS. My employer's booster clinic dates were always booked solid by the time I tried to schedule. So I went to the CVS website on Monday AM and there were tons of appointments for that PM. Had such an easy experience that I scheduled my kids there for their flu  + COVID-19 primary series.

 
YLE current state of affairs 11/8

Worth a read, but tl;dr; after steady declines, cases have now begun to plateau in the US, which is a tad worrisome heading into winter months, and seeing what's happening overseas with countries with higher vaccination rates than us. 
Thanks for the link, some interesting stuff in there.  The one thing that stood out to me was the statement:

This may confirm that SARS-CoV-2 is, in fact, seasonal
I've not really understood the reluctance of many on the seasonality front.  To me the seasonality seemed fairly indisputable by last winter at the latest.  You can find those animated charts of spread level by county over time and visually see the waves moving around the country.  It's a little unsatisfying that I haven't seen anybody come up with a compelling cause for the seasonality, but the data paint a pretty clear picture that whatever the mechanism, the effect is there.

 
Thanks for the link, some interesting stuff in there.  The one thing that stood out to me was the statement:

I've not really understood the reluctance of many on the seasonality front.  To me the seasonality seemed fairly indisputable by last winter at the latest.  You can find those animated charts of spread level by county over time and visually see the waves moving around the country.  It's a little unsatisfying that I haven't seen anybody come up with a compelling cause for the seasonality, but the data paint a pretty clear picture that whatever the mechanism, the effect is there.
This is the second year in a row (out of two) when covid-19 has spread about how you would predict if it was a seasonal illness spread most easily when people are indoors.  At this point, I think the presumption should be that seasonality is a thing with covid until there are data conclusively showing otherwise.

 
This is a misleading story. 

"More than 10,000 patients were diagnosed with covid in a U.S. hospital last year after they were admitted for something else."

That doesn't mean they contracted the disease WHILE in the hospital.  I'm sure a good number had it when they came in and were either not aware that they had it or were asymptomatic when they went in.  I'm sure many DID contract the disease while in a hospital, but I don't think the conclusion can be drawn from the data presented.

 
This is a misleading story. 

"More than 10,000 patients were diagnosed with covid in a U.S. hospital last year after they were admitted for something else."

That doesn't mean they contracted the disease WHILE in the hospital.  I'm sure a good number had it when they came in and were either not aware that they had it or were asymptomatic when they went in.  I'm sure many DID contract the disease while in a hospital, but I don't think the conclusion can be drawn from the data presented.
I agree it's not know how many had it when they went in. Given the top 9 reasons for their admission, it looks like only #8 would cover typical COVID symptoms.

1 - Sepsis
2 - Acute kidney failure
3 - Sepsis due to Escherichia coli [E. coli]
4 - Chronic kidney disease
5 - Schizoaffective disorder
6 - Heart attack
7 - Hypertensive heart disease with heart failure
8 - Acute and chronic respiratory failure
9 - Schizophrenia

That study also counted mainly people over 65, so the number of patients who either contracted it on discovered they had it in the hospital is likely much higher.

 
Thanks for the link, some interesting stuff in there.  The one thing that stood out to me was the statement:

I've not really understood the reluctance of many on the seasonality front.  To me the seasonality seemed fairly indisputable by last winter at the latest.  You can find those animated charts of spread level by county over time and visually see the waves moving around the country.  It's a little unsatisfying that I haven't seen anybody come up with a compelling cause for the seasonality, but the data paint a pretty clear picture that whatever the mechanism, the effect is there.
I think that everyone thought that it would eventually fall into a seasonal pattern. Vaccination helped and with boosters this time of year happening now, it should push the virus in that direction. And then we do it again next fall (new mRNA formula for whatever the prevalent variants are with 100 days to manufacture) with covid/flu combo shots in September/October for all. 
 

Hopefully there is a vax for infants by then. My friend’s daughter is out of the hospital after two weeks. Still very limited spleen function, blood clots in stomach and legs, and will need treatments forever. Caught covid at 3months and all these complications showed up two months later. 

 
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YLE current state of affairs 11/8

Worth a read, but tl;dr; after steady declines, cases have now begun to plateau in the US, which is a tad worrisome heading into winter months, and seeing what's happening overseas with countries with higher vaccination rates than us. 


Related: Take with massive grain of salt, as it's purely anecdotal, but the number of cases (breakthrough and otherwise) among people in my extended circle seem to be on the rise over the last week or two. 

One is a nurse friend who was boosted Pfizer who is in good heath, around 40yo... needed some supplemental O2 and is on day 11 of feeling like ####, with a 3 day stretch of fever approaching 104 despite treatment. Presumably she picked up a large initial viral load at the hospital she works at. 

 
Related: Take with massive grain of salt, as it's purely anecdotal, but the number of cases (breakthrough and otherwise) among people in my extended circle seem to be on the rise over the last week or two. 

One is a nurse friend who was boosted Pfizer who is in good heath, around 40yo... needed some supplemental O2 and is on day 11 of feeling like ####, with a 3 day stretch of fever approaching 104 despite treatment. Presumably she picked up a large initial viral load at the hospital she works at. 
Delta+?

 
The Food and Drug Administration could soon grant emergency authorization to monoclonal antibodies from drugmaker Regeneron for what is known as pre-exposure prophylaxis, or PrEP, against Covid-19.

Update: On Monday, Regeneron released findings from a late-stage trial that a single dose of its antibody cocktail reduced the risk of contracting Covid by 81.6 percent in the two to eight months period following the drug’s administration.

Experts also anticipate that if Covid-19 rates continue to fall and oral antivirals such as Merck’s molnupiravir or Pfizer’s Paxlovid are approved as treatment, this could ease demand for antibodies as treatment while freeing up health care providers’ capacity to provide PrEP.

James Hoyer, who leads West Virginia’s Covid response task force, remains bullish on PrEP’s prospects, saying, “If they’ll give us one more tool to get past the pandemic, trust me, we’ll figure out a way to get it to the people.”

 
Related: Take with massive grain of salt, as it's purely anecdotal, but the number of cases (breakthrough and otherwise) among people in my extended circle seem to be on the rise over the last week or two. 

One is a nurse friend who was boosted Pfizer who is in good heath, around 40yo... needed some supplemental O2 and is on day 11 of feeling like ####, with a 3 day stretch of fever approaching 104 despite treatment. Presumably she picked up a large initial viral load at the hospital she works at. 
A breakthrough with a booster shot??  I thought that would be highly unlikely?

 
A breakthrough with a booster shot??  I thought that would be highly unlikely?
Highly unlikely indeed, which is why I felt it worth mentioning in here. 

Odds are she got hit with a very high viral load, working in healthcare... but it also shows while protection is extremely good, it's not perfect. 

 
This is the second year in a row (out of two) when covid-19 has spread about how you would predict if it was a seasonal illness spread most easily when people are indoors.  At this point, I think the presumption should be that seasonality is a thing with covid until there are data conclusively showing otherwise.
Yes, most of the people who subscribe to seasonality point to southern summers = people inside and northern winters = people inside.  I do think that's on the right track, but there seems to be another factor on top of that.  Otherwise I'm not sure why, e.g., the upper midwest would peak in October/November of 2020, a month or two before the Mid Atlantic - it's not like people in Minnesota all stop hanging out inside in January.  At least, I would think not.  I've never lived there, maybe the Viking heritage makes them odd.  Regardless, I largely agree and don't want to turn it into a major thread de-rail.

 
I agree it's not know how many had it when they went in. Given the top 9 reasons for their admission, it looks like only #8 would cover typical COVID symptoms.

1 - Sepsis
2 - Acute kidney failure
3 - Sepsis due to Escherichia coli [E. coli]
4 - Chronic kidney disease
5 - Schizoaffective disorder
6 - Heart attack
7 - Hypertensive heart disease with heart failure
8 - Acute and chronic respiratory failure
9 - Schizophrenia

That study also counted mainly people over 65, so the number of patients who either contracted it on discovered they had it in the hospital is likely much higher.
1 is a diagnosis associated with symptomatic infection, plus 2, 6 and 7 could be complications of covid. Surprised stroke isn’t on there as well - I saw a covid patient suffer one of the biggest strokes of my career, less than 24 hours after they were admitted.

And I don’t know this for sure, but I bet people with mental illness are less likely to accept vaccination. Numbers 5 and 9 can both be paranoid and have unusual belief systems, analogous to some of the concepts suggested by more ardent anti-vaxxers.

 
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