I happen to know Dr Meister personally, ever since we had our first high school jobs working at McDonalds where he was known as the Burger Meister and we have kept in touch ever since. I just called him and asked for a further clarification on the "tissue issue" thing. I asked if he could put it into layman's terms as much as possible, as I'm really not familar with medical terms. We had a 30 minute discussion that started off with "the hand bone is connected to the wrist bone..."It turns out that all this stuff is connected to Gore's knee bone so it could be serious!!!