I hold players (barring injury) for Week 1. Stinking it up in the first week can be known to happen, and way to early to start panicking.
If they stink it up in Week 2, I see that as a trend. Now, I just don't go jettisoning players willy-nilly for the waiver flavor of the week -- but I do reevaluate and pull triggers on players and situations that seem to align.
For instance, I drafted Kenny Britt as a WR3 with the belief that he has WR2 upside. He sucked in WK 1, with one catch off of two targets. I would write this off as a low-scoring game where TEN had to manage the game instead of rely on moving the change.Locker only threw 20 times overall for 125 yards.
So I am not going to drop Britt for a guy like Hankerson, given that I know Britt has more talent and opportunity, and the revamped Titans O-line are settling in which should give Locker more time to find Kenny downfield. Would I have dropped him for Edelman? Tougher call, but answer is still no -- if Britt and TEN play to their middling ability, I think he performs better than Edelman who is a great short term play, but someone I expect will fade in and out over the season depending on the health of other receivers around him.
This week, TEN is up against the Texans, who play tough but coughed up 4 to Rivers. So it's a matchup Britt could take advantage of, especially if HOU continues to play the run well as they did against the Chargers last week and force Locker to throw.
If Britt craps up again and it's Nate Washington who looks like he's getting all the love and targets? Then yes, will be looking hard at the wire or to trade for guys I think have a comparable talent and situation, like T.Y. Hilton (great hands and speed with a solid QB tossing the rock) or perhaps even a guy like Marlon Brown (can take away #2 slot in Jones' absence if he continues to excel) or even Hankerson (providing a spark in a pool of meh receivers across the field from Garcon) if they both play well and see high numbers of targets.
Pulling the trigger in an informed way that mitigates risk and aligns with how I value players and their situations has helped me get a jump on guys a little earlier in the season. Waiting until after week 4 when a quarter of the season is over and early trends are widely known as fact can be too late to make a move.