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*** OFFICIAL *** COVID-19 CoronaVirus Thread. Fresh epidemic fears as child pneumonia cases surge in Europe after China outbreak. NOW in USA (12 Viewers)

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He has no idea what he’s talking about. That drug has nothing to do with ivermectin, structurally or mechanistically. And even it it proves effective (still a big IF), vaccines will remain the optimal way to curb the virus.
Agree 100% on vaccinations being the best way to curb the virus. I am just excited every time I see a promising drug because therapeutics to help keep people from adverse outcomes to go along with the vaccines is a huge win-win for beating this thing. 

By the way, you have been an awesome source of info on this board. Some of the posts you shared helped convince my wife who has an autoimmune issue to finally get vaxxed.  :hifive:

 
Agree 100% on vaccinations being the best way to curb the virus. I am just excited every time I see a promising drug because therapeutics to help keep people from adverse outcomes to go along with the vaccines is a huge win-win for beating this thing. 
Absolutely. One point Delta has driven home is that we need an all-of-the-above approach to fighting the virus. I'm in favor of any therapeutic that works. They should serve as our second line of defense, after vaccines.

 
Agree 100% on vaccinations being the best way to curb the virus. I am just excited every time I see a promising drug because therapeutics to help keep people from adverse outcomes to go along with the vaccines is a huge win-win for beating this thing. 

By the way, you have been an awesome source of info on this board. Some of the posts you shared helped convince my wife who has an autoimmune issue to finally get vaxxed.  :hifive:
Yeah, forgive me if I’m not super optimistic about antiviral therapeutics. But outside of HIV and hepatitis C, they’ve been pretty underwhelming. Including remdesivir. Another arrow in the quiver can’t hurt, I guess.

It will be really (not) interesting to hear the Big Pharma conspiracies, if the drug turns out to be as good as advertised. And don’t forget about the potential for long term adverse effects from an EUA drug. 💊🤢😱

Glad I helped influence your wife. I get super frustrated repeating points to posters who remain willfully ignorant, but credit @Doug Bfor reminding me there are people on the sidelines who may benefit.

 
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Newly discovered biomarker predicts COVID-19 death days in advance

https://newatlas.com/medical/ekg-heart-electrical-activity-predicts-coronavirus-death-mount-sinai/

Could be pretty big 
That's interesting, and a cheap/easy test.

But it still lacks the sensitivity to change a patient’s level of care in the absence of other findings. And there’s nothing specific therapeutically to be done in a vacuum, beyond preemptively transferring to an ICU bed, which are in short supply many places. In our hospital at least, ICU docs are being anything but proactive, because they’re already overwhelmed and/or burnt out.

I could get on-board if EKGs were used instead of the sh!tload of other blood tests covid patients get routinely, but do next to nothing to influence their care.

TBH, treating covid is pretty straightforward, albeit labor intensive for the sickest patients. Oxygen, dexamethasone, prone ventilation, clot prophylaxis +/- Tylenol and cough meds are all most floor patients need. After that, it’s a crapshoot whether they crash and burn, or recover in a few days.

 
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That's interesting, and a cheap/easy test.

But it still lacks the sensitivity to change a patient’s level of care in the absence of other findings. And there’s nothing specific therapeutically to be done in a vacuum, beyond preemptively transferring to an ICU bed, which are in short supply many places. In our hospital at least, ICU docs are being anything but proactive, because they’re already overwhelmed and/or burnt out.

I could get on-board if EKGs were used instead of the sh!tload of other blood tests covid patients get routinely, but do next to nothing to influence their care.

TBH, treating covid is pretty straightforward, albeit labor intensive for the sickest patients. Oxygen, dexamethasone, prone ventilation, clot prophylaxis +/- Tylenol and cough meds are all most floor patients need. After that, it’s a crapshoot whether they crash and burn, or recover in a few days.
preach.

and agreed the LoQRS isn’t really gonna change outcomes. Neat, cheap trick but I don’t see it being ground-breaking.

 
That's interesting, and a cheap/easy test.

But it still lacks the sensitivity to change a patient’s level of care in the absence of other findings. And there’s nothing specific therapeutically to be done in a vacuum, beyond preemptively transferring to an ICU bed, which are in short supply many places. In our hospital at least, ICU docs are being anything but proactive, because they’re already overwhelmed and/or burnt out.

I could get on-board if EKGs were used instead of the sh!tload of other blood tests covid patients get routinely, but do next to nothing to influence their care.

TBH, treating covid is pretty straightforward, albeit labor intensive for the sickest patients. Oxygen, dexamethasone, prone ventilation, clot prophylaxis +/- Tylenol and cough meds are all most floor patients need. After that, it’s a crapshoot whether they crash and burn, or recover in a few days.
I guess I was thinking more in line with this new wave of therapeutics. Could assist with allocation of scarce or "risky" interventions, but your point is absolutely made regarding lack of current treatment options. 

 
I’m sure some will get a kick out of the interesting way that my company’s HR department is handling COVID quarantine. A few weeks ago my co-worker was sick with what turned out to be a sinus infection. She tested negative but was forced to quarantine for 10 despite the test results and being fully vaccinated.

On Thursday she calls to let us know that her niece who she lives with tested positive before a surgery but no one had symptoms. HRs response this time - cleared to go back to work and not even asked to get tested. I’m very happy because we’re busier than we ever have been and have no one to replace her, but neither response seems right.

 
ignatiusjreilly said:
Absolutely. One point Delta has driven home is that we need an all-of-the-above approach to fighting the virus. I'm in favor of any therapeutic that works. They should serve as our second line of defense, after vaccines.
Seems obvious, but this has become a red-blue thing so . . .

 
I’m sure some will get a kick out of the interesting way that my company’s HR department is handling COVID quarantine. A few weeks ago my co-worker was sick with what turned out to be a sinus infection. She tested negative but was forced to quarantine for 10 despite the test results and being fully vaccinated.

On Thursday she calls to let us know that her niece who she lives with tested positive before a surgery but no one had symptoms. HRs response this time - cleared to go back to work and not even asked to get tested. I’m very happy because we’re busier than we ever have been and have no one to replace her, but neither response seems right.
WTF? 😂😂
 

 
It's been so amazing and disheartening to watch. I knew we were tribal, but I honestly didn't know it was that bad. We're talking basic stuff, and we can't agree on it.
I’ve been getting more people coming in to get vaccinated who tell me they ‘really didn’t want to get this shot’. Part of me wants to ask them why but the smart part of me doesn’t ask because I know they don’t have a good answer and nothing good would come from the question.

The other extreme isn’t great either. Some of the behavior I’ve seen from the booster seekers has disheartening. We had to stop booster walk-ins because we were so overwhelmed that we couldn’t do our job safely. The reaction from some has been so nasty and aggressive that I don’t even know how to respond.

 
Terminalxylem said:
That's interesting, and a cheap/easy test.

But it still lacks the sensitivity to change a patient’s level of care in the absence of other findings. And there’s nothing specific therapeutically to be done in a vacuum, beyond preemptively transferring to an ICU bed, which are in short supply many places. In our hospital at least, ICU docs are being anything but proactive, because they’re already overwhelmed and/or burnt out.

I could get on-board if EKGs were used instead of the sh!tload of other blood tests covid patients get routinely, but do next to nothing to influence their care.

TBH, treating covid is pretty straightforward, albeit labor intensive for the sickest patients. Oxygen, dexamethasone, prone ventilation, clot prophylaxis +/- Tylenol and cough meds are all most floor patients need. After that, it’s a crapshoot whether they crash and burn, or recover in a few days.
just want to let you know that your input is incredibly appreciated, particularly in light of the misinformation, conspiracies, denial and pure idiocy that you've been confronted with in here.  I could never have your patience.

 
Seems obvious, but this has become a red-blue thing so . . .
Back during the whole Kaepernick/Trump stuff in 2018, I saw a tweet from a comedian that said something like “I can’t believe liberals got football in the divorce.” That’s kind of how I feel about Covid response. The left got vaccines and masks, the right got therapeutics. I suppose one could explore the core philosophical differences in our political system to explain how we got to this point, but it mostly just feels like someone arbitrarily divvied up assets

 
I’m sure some will get a kick out of the interesting way that my company’s HR department is handling COVID quarantine. A few weeks ago my co-worker was sick with what turned out to be a sinus infection. She tested negative but was forced to quarantine for 10 despite the test results and being fully vaccinated.

On Thursday she calls to let us know that her niece who she lives with tested positive before a surgery but no one had symptoms. HRs response this time - cleared to go back to work and not even asked to get tested. I’m very happy because we’re busier than we ever have been and have no one to replace her, but neither response seems right.
My general experience with HR throughout my career has been that they often prioritize bureaucratic initiatives at the expense of common sense 

 
So my oldest (7) started having a sore throat and cough Saturday afternoon.  Added sever congestion and a low-grade fever yesterday.  So off to the doctor today, where they will also do a covid test . . . . 

He hasn't been anywhere but school, where they wear masks except lunch, recess, and snack.  They did have "Olympics" last week so were outside playing games unmasked for longer.  He also played with neighborhood kids outside during the week -- trampoline, running around etc.

 
Some interesting thoughts on the 8-week surge pattern: https://www.nytimes.com/2021/09/01/briefing/delta-peak-covid-caseload.html

It's paywalled, so here's the upshot:

"Since the Covid virus began spreading in late 2019 cases have often surged for about two months — sometimes because of a variant, like Delta — and then declined for about two months.

Epidemiologists do not understand why. Many popular explanations, like seasonality or the ebbs and flows of social distancing, are clearly insufficient, if not wrong. The two-month cycle has occurred during different seasons of the year and occurred even when human behavior was not changing in obvious ways.

The most plausible explanations involve some combination of virus biology and social networks. Perhaps each virus variant is especially likely to infect some people but not others — and once many of the most vulnerable have been exposed, the virus recedes. And perhaps a variant needs about two months to circulate through an average-sized community.

Human behavior does play a role, with people often becoming more careful once caseloads begin to rise. But social distancing is not as important as public discussion of the virus often imagines. "We've ascribed far too much human authority over the virus," as Michael Osterholm, an infectious-disease expert at the University of Minnesota, has told me."

 
🤣 Told ya the pill was coming. merck is beating pfizer to the punch.

You don't have a clue what you are talking about. You will NEVER prevent this. Molnupiravir (Merckmectin) is about to be phased in as I told you all. Oh, look at that fauci is praising it AND is a protease inhibitor.

Guess you guys will be taking the 'horse paste' after all. 


Just like I said. They would take ivermectin and make their new drug out of it and charge an arm and a leg. The jab will be phased out once they get this approved. They can make so much more $ with it.

https://www.zerohedge.com/covid-19/pfizer-launches-final-study-covid-drug-thats-suspiciously-similar-ivermectin?fbclid=IwAR35Dy4IQHeSZtuoN3uzs6mB801PC7FOYq0CRyW5zUizagJjE_plJEuh5jQ


This kind of stuff is better received in the PSF.  Here, we deal with reality and the reality is Ivermectin is a SIGNIFICANTLY different drug from Molnupiravir.  You can look at the fact that Ivermectin is an approach to neurotransmitters in the body while Molnupiravir is an attempt to genetically modify the virus.  If you are under the impression they are remotely similar, you are wrong.

 
A study on the frequency of myocarditis after COVID-19 mRNA vaccination will be released on Monday. 
It's up: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2784800

There were 15 cases of confirmed myocarditis (out of 2,392,924) in the vaccinated group (2 after the first dose and 13 after the second), for an observed incidence of 0.8 cases per 1 million first doses and 5.8 cases per 1 million second doses over a 10-day observation window (Table 1). All were men, with a median (IQR) age of 25 (20-32) years. Among unexposed individuals, there were 75 cases of myocarditis (out of 1,577,741) during the study period, with 39 (52%) men and median (IQR) age of 52 (32-59) years. The IRR for myocarditis was 0.38 (95% CI, 0.05-1.40) for the first dose and 2.7 (95% CI, 1.4-4.8) for the second dose. Sensitivity analyses using vaccinated individuals as their own controls showed similar findings (Table 1).

Of the patients with myocarditis postvaccination, none had prior cardiac disease (Table 2). Eight patients received BNT162b2 and 7 received mRNA-1273. All were hospitalized and tested negative for SARS-CoV-2 by polymerase chain reaction on admission. Fourteen (93%) reported chest pain between 1 to 5 days after vaccination. Symptoms resolved with conservative management in all cases; no patients required intensive care unit admission or readmission after discharge.

 
This kind of stuff is better received in the PSF.  Here, we deal with reality and the reality is Ivermectin is a SIGNIFICANTLY different drug from Molnupiravir.  You can look at the fact that Ivermectin is an approach to neurotransmitters in the body while Molnupiravir is an attempt to genetically modify the virus.  If you are under the impression they are remotely similar, you are wrong.
That's unpossible, his research was peer-reviewed on parler.

 
What's the current science around people who have both had COVID and are vaccinated and how likely they are to get/spread delta if they have been exposed to it?  

 
RIP mom. I'll miss you dearly. 

Double vaxxed many months ago. Started with what she said was a cold, as I've been vaccinated. Last Monday both her and her husband test positive and mom admitted with low oxygen levels. 

Both pneumonia and covid pneumonia by Wednesday. 

She refused the ventilator, so tried everything up until that point. 

At least they allowed my step dad to be there with her even though he was positive as well to hold her hand when she passed. 

Eff this sickness. Selfishly I wished it was stroke, heart attack, etc. Anything except cancer as she would have suffered much longer. 

Love ya mom. Take care of granny and my sister.  I'll see you someday, just hope not soon. 

 
RIP mom. I'll miss you dearly. 

Double vaxxed many months ago. Started with what she said was a cold, as I've been vaccinated. Last Monday both her and her husband test positive and mom admitted with low oxygen levels. 

Both pneumonia and covid pneumonia by Wednesday. 

She refused the ventilator, so tried everything up until that point. 

At least they allowed my step dad to be there with her even though he was positive as well to hold her hand when she passed. 

Eff this sickness. Selfishly I wished it was stroke, heart attack, etc. Anything except cancer as she would have suffered much longer. 

Love ya mom. Take care of granny and my sister.  I'll see you someday, just hope not soon. 
OMG so sorry for your loss. Hearing more and more if these stories of fully vaxxed people dying from covid.

 
Why Are Americans Still—Still!—Wearing Cloth Masks?

It’s long past time for an upgrade
From that link:

----------------------

And there is still much to learn about the effectiveness of masking. Even the most rigorous studies on masking have limitations, said Osterholm, largely because of shortcomings in their methodology. Cloth masks are less protective than surgical masks, but exactly how much less remains uncertain. Roger Chou, an epidemiologist at Oregon Health & Science University who tracks mask studies, told me in an email that he “really has not found much evidence” on the effectiveness of cloth versus surgical masks in stopping the spread of COVID-19 in communities, even though he said that plenty of other data back up their effectiveness. The most important thing, Chou said, “is to wear a mask, whether it is a surgical mask or cloth mask.”

----------------------

Sides of the mouth, researchers: pick one.

I'll maintain that cloth masks (a) worn consistently over the nose (b) without big gaps under the eyes or at the sides ... cloth masks like that protect well enough. I can see occupational needs for *95s (e.g. public-facing workers), but not for grocery-getting, in-and-out retail, or general errand-running..

 
Why Are Americans Still—Still!—Posting About Wearing Cloth Masks?
Not sure if this was a typo but yeah - I’ve been harping on the mask debate for months now.  It’s dumb but I guess I think it’s dumb because I understand both sides of the “debate” - the idea of something is better than nothing and it’s a courtesy versus it being such a (relatively) small risk increase.  I also think it annoys me because around here it’s not even a debate any more - we ditched masking a while back and unless there’s a much worse variant than Delta I don’t see things ever changing.

 
RIP mom. I'll miss you dearly. 

Double vaxxed many months ago. Started with what she said was a cold, as I've been vaccinated. Last Monday both her and her husband test positive and mom admitted with low oxygen levels. 

Both pneumonia and covid pneumonia by Wednesday. 

She refused the ventilator, so tried everything up until that point. 

At least they allowed my step dad to be there with her even though he was positive as well to hold her hand when she passed. 

Eff this sickness. Selfishly I wished it was stroke, heart attack, etc. Anything except cancer as she would have suffered much longer. 

Love ya mom. Take care of granny and my sister.  I'll see you someday, just hope not soon. 
So sorry for your loss. 

 
RIP mom. I'll miss you dearly. 

Double vaxxed many months ago. Started with what she said was a cold, as I've been vaccinated. Last Monday both her and her husband test positive and mom admitted with low oxygen levels. 

Both pneumonia and covid pneumonia by Wednesday. 

She refused the ventilator, so tried everything up until that point. 

At least they allowed my step dad to be there with her even though he was positive as well to hold her hand when she passed. 

Eff this sickness. Selfishly I wished it was stroke, heart attack, etc. Anything except cancer as she would have suffered much longer. 

Love ya mom. Take care of granny and my sister.  I'll see you someday, just hope not soon. 


Oh man, fully vaccinated too?  Sorry for your loss.  This is scary.  :(  

 
RIP mom. I'll miss you dearly. 

Double vaxxed many months ago. Started with what she said was a cold, as I've been vaccinated. Last Monday both her and her husband test positive and mom admitted with low oxygen levels. 

Both pneumonia and covid pneumonia by Wednesday. 

She refused the ventilator, so tried everything up until that point. 

At least they allowed my step dad to be there with her even though he was positive as well to hold her hand when she passed. 

Eff this sickness. Selfishly I wished it was stroke, heart attack, etc. Anything except cancer as she would have suffered much longer. 

Love ya mom. Take care of granny and my sister.  I'll see you someday, just hope not soon. 
Dang that is terrible.  I am very sorry for you and your family.

 
Unfotunately, as a greater percentage of Americans get vaccinated, we will have more of these sotries that hit closer to home


Yep.  It could happen to any of us and our loved ones who are trying to do the right thing.  I'm really sorry for loss Fishboy.  

 
From that link:

----------------------

And there is still much to learn about the effectiveness of masking. Even the most rigorous studies on masking have limitations, said Osterholm, largely because of shortcomings in their methodology. Cloth masks are less protective than surgical masks, but exactly how much less remains uncertain. Roger Chou, an epidemiologist at Oregon Health & Science University who tracks mask studies, told me in an email that he “really has not found much evidence” on the effectiveness of cloth versus surgical masks in stopping the spread of COVID-19 in communities, even though he said that plenty of other data back up their effectiveness. The most important thing, Chou said, “is to wear a mask, whether it is a surgical mask or cloth mask.”

----------------------

Sides of the mouth, researchers: pick one.

I'll maintain that cloth masks (a) worn consistently over the nose (b) without big gaps under the eyes or at the sides ... cloth masks like that protect well enough. I can see occupational needs for *95s (e.g. public-facing workers), but not for grocery-getting, in-and-out retail, or general errand-running..


Kids are not going to wear an N95 or KN95 all day.  Is it worth getting them to wear surgical over cloth though?  

 
gianmarco said:
Why Are Americans Still—Still!—Posting About Wearing Cloth Masks?
Because a bunch of Americans still think cloth masks help.

This is no different than saying why do americans still post about vaccines? 

We know vaccines work and we want people to listen. 

I know cloth masks are just for virtue signaling or avoiding conflict and I want people to upgrade and not kill granny. 

 
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