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*** OFFICIAL *** COVID-19 CoronaVirus Thread. Fresh epidemic fears as child pneumonia cases surge in Europe after China outbreak. NOW in USA (15 Viewers)

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yeah yeah :P  

I guess it will remain "optional" until there aren't enough teachers/subs to conduct teaching
Louisiana - 48

South Carolina - 44 WooHoo!!!!

SC has approached this pandemic from day one like it didn't exist, don't see them changing anytime soon. I heard last week that SC has received something like $3B in Federal aid toward education during COVID. I'm not sure where it went but it hasn't gone to the teachers, it hasn't gone into new air handling systems although at the beginning of the year they promised they were installing them. It hasn't gone into new virtual programs, my daughter has the benefit of a home office but runs everything off her personal computer. It's a sham around here and I feel for the profession because universities are literally shutting down Education programs because no one is signing up to be a teacher these days.

In 5 years time there is going to be a massive shortage of teachers in this country and it's going to be really tough to overcome.

 
Louisiana - 48

South Carolina - 44 WooHoo!!!!

SC has approached this pandemic from day one like it didn't exist, don't see them changing anytime soon. I heard last week that SC has received something like $3B in Federal aid toward education during COVID. I'm not sure where it went but it hasn't gone to the teachers, it hasn't gone into new air handling systems although at the beginning of the year they promised they were installing them. It hasn't gone into new virtual programs, my daughter has the benefit of a home office but runs everything off her personal computer. It's a sham around here and I feel for the profession because universities are literally shutting down Education programs because no one is signing up to be a teacher these days.

In 5 years time there is going to be a massive shortage of teachers in this country and it's going to be really tough to overcome.


I'm hopeful that in 5 years when can work out both the issues with virtual classrooms but also the impacts to social skills.   More virtual means less teachers needed and more TAs.  Let's get our most gifted teachers in front of the most students possible.  We should consider in person students and remote teachers.

 
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For those looking for tests here is a website that tracks when available to purchase: https://www.nowinstock.net/home/healthhousehold/covidtests/
Thanks for this.  Just picked up the abbott tests from Walgreens thanks to the site alerting me they had them in stock after being out earlier today.  The limit is 4 packs.
How did you get that link to show you specific locations? I couldn't figure out how to get it to show stores in my local area.

EDIT: Never mind -- I see it's online orders only. Unless I'm overlooking something.

 
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How did you get that link to show you specific locations? I couldn't figure out how to get it to show stores in my local area.

EDIT: Never mind -- I see it's online orders only. Unless I'm overlooking something.
Try this one: https://brickseek.com/walmart-inventory-checker/?sku=142089281

You can change the UPC code to anything with a UPC. You can also check Target (from menu at the top) and a few other retailers that might carry them. 

 
You can change the UPC code to anything with a UPC. You can also check Target (from menu at the top) and a few other retailers that might carry them. 
Well, well ... two of our local WalMarts supposedly have some BinaxNow in stock. Will have to swing by in a bit.

This past Sunday, I did find a nearby CVS that's selling FreeFlow rapid tests. They're not on display, they're behind the counter and customers have to ask for them. They limit customers to two boxes (these come one to a box).

I bought two Sunday and two more yesterday. Used one this morning for my wife to test for her work. Well, now I have a few places to check locally.
 

 
Well, well ... two of our local WalMarts supposedly have some BinaxNow in stock. Will have to swing by in a bit.

This past Sunday, I did find a nearby CVS that's selling FreeFlow rapid tests. They're not on display, they're behind the counter and customers have to ask for them. They limit customers to two boxes (these come one to a box).

I bought two Sunday and two more yesterday. Used one this morning for my wife to test for her work. Well, now I have a few places to check locally.
 
GL! I'm sure that's tied to their electronic system somehow, so I'd guess it may not necessarily mean there are some on the shelf, but hopefully they have some for you. 

 
GL! I'm sure that's tied to their electronic system somehow, so I'd guess it may not necessarily mean there are some on the shelf, but hopefully they have some for you. 
If those WalMarts have them ... they're likely behind the pharmacy counter and not on floor display.

Using the FreeFlow test for the first time this morning, I actually thought it was a little easier to administer than the BinaxNOW. With the FreeFlow, the reagent mixes with the swabbed sample in a little pre-filled tube -- then you apply drops of the mixture to the test strip.

 
Ro.co (telehealth company) bought a ton of home tests and is selling them for $30 for a pack of 2 with free shipping.

https://covid.ro.co/
I have no experience with that brand but they’ve been pretty poorly reviewed online and apparently have a 3 month expiration date from date of manufacture. That’s much shorter than other ones. May not be an issue for some but just sharing info. 

 
I have no experience with that brand but they’ve been pretty poorly reviewed online and apparently have a 3 month expiration date from date of manufacture. That’s much shorter than other ones. May not be an issue for some but just sharing info. 
yeah haven't used these, just know they're available.  most bad reviews seem to be user error, but you're right shelf life seems to be 6 weeks-4 months.   

 
If those WalMarts have them ... they're likely behind the pharmacy counter and not on floor display.

Using the FreeFlow test for the first time this morning, I actually thought it was a little easier to administer than the BinaxNOW. With the FreeFlow, the reagent mixes with the swabbed sample in a little pre-filled tube -- then you apply drops of the mixture to the test strip.
Really? Interesting. I haven't checked in the last couple of weeks bc I'm already stocked up, but our Walmart (Neighborhood Market, which also has a pharmacy) had them on the shelf, by the at-home drug tests, etc. 

 
Vice Principal called at end of day. My 7th grader was exposed to a Covid positive kid yesterday. Figured it was a kid that sat in front of her. Both were masked. Came home and said feels ok but has some sniffles. Temp is 99.2. could be anything. Can go to school if asymptomatic and wear a mask is recommended which she already does. If a fever will Covid test in morning.

 
Really? Interesting. I haven't checked in the last couple of weeks bc I'm already stocked up, but our Walmart (Neighborhood Market, which also has a pharmacy) had them on the shelf, by the at-home drug tests, etc. 
Yep, for real.

And Brickseek.com was :moneybag:  -- our closest WalMart Neighborhood Market did, in fact, have BinaxNOW tests in stock just now. As I surmised, there were indeed behind the pharmacy counter and could be purchased by request. 2 box limit per customer -- but that's four tests per trip. Going to CVS for the FreeFlow tests limited me to two tests per trip.

Our WalMarts, and Neighborhood Markets, and Walgreens ... all those places did have dozens of BinaxNOW tests on floor display all through the fall. It wasn't until the weekend of December 17-18 that they vanished from the shelves. I was actually at our local Walgreens on Thursday, December 16th looking at a big display of BinaxNOW tests. There were so many ... I told myself "Meh, they'll have plenty later!" and so just bought one box   :wall:

 
Yep, for real.

And Brickseek.com was :moneybag:  -- our closest WalMart Neighborhood Market did, in fact, have BinaxNOW tests in stock just now. As I surmised, there were indeed behind the pharmacy counter and could be purchased by request. 2 box limit per customer -- but that's four tests per trip. Going to CVS for the FreeFlow tests limited me to two tests per trip.

Our WalMarts, and Neighborhood Markets, and Walgreens ... all those places did have dozens of BinaxNOW tests on floor display all through the fall. It wasn't until the weekend of December 17-18 that they vanished from the shelves. I was actually at our local Walgreens on Thursday, December 16th looking at a big display of BinaxNOW tests. There were so many ... I told myself "Meh, they'll have plenty later!" and so just bought one box   :wall:
:lol: glad BrickSeek worked for ya, GB! 

 
Just got notice of an ‘indirect exposure’ for our Pre-K girl. I asked if that just meant someone outside of class in the lunchroom or recess and she responded that it just meant no close contact for more 15 minutes. In a classroom that’s best described as being no different than any daycare, I’m not sure any positive in the class could be ‘indirect’. But I also doubt that they’d waste time notifying us about a case outside her class.

So is it safe to assume that she was exposed and they’re just trying to avoid quarantining the whole class?

 
Just saw a news blurb:

The CDC is considering updating its mask guidance to recommend that people opt for N95 or KN95 masks rather than cloth face coverings. ---- YA THINK!?! :wall:  

And the Pres is considering offering higher quality masks to all Americans, similar to the rapid test distribution. ---- So we could expect these, if that comes to pass, around Q3 of 2023? :wall:  

 
Pounding headache, little head congestion....

No tests to be found. Although I haven't been around anyone since like 1/2 besides my wife and kid :unsure:

 
nothing earth shattering, but interesting info I thought...

New (Pre-print, lab) study: COVID Loses 50% Of Its Ability To Infect After Ten Seconds In The Air

A new study (here's a link) shows that COVID-19 quickly loses its ability to infect people seconds after it becomes airborne. Researchers with the University of Bristol's Aerosol Research Center found that the virus loses about 50% of its ability to infect within ten seconds in a typical office environment.

Within 20 minutes of becoming airborne, the virus loses 90% of its ability to infect people.

"A decrease in infectivity to ∼10 % of the starting value was observable for SARS-CoV-2 over 20 minutes, with a large proportion of the loss occurring within the first 5 minutes after aerosolization," the researchers wrote in the pre-print study.

Because the virus spreads in tiny droplets expelled from the lungs, it quickly loses the ability to infect people when exposed to dry air. However, when the relative humidity is higher, the virus will keep its ability to infect people for more extended periods of time.

When they tested samples in the air with 90% humidity, which is the equivalent of a shower, they found that 52% of particles were still infectious after five minutes. However, by 20 minutes, just ten percent of the particles were still infectious.

The researchers also noted that the pH levels rapidly increase when the carbon dioxide in the environment decreases.

"People have been focused on poorly ventilated spaces and thinking about airborne transmission over meters or across a room. I'm not saying that doesn't happen, but I think still the greatest risk of exposure is when you're close to someone," Professor Jonathan Reid, director of the University of Bristol's Aerosol Research Centre and the study's lead author, said, according to The Guardian. "When you move further away, not only is the aerosol diluted down, there's also less infectious virus because the virus has lost infectivity [as a result of time]."

 
Yep, for real.

And Brickseek.com was :moneybag:  -- our closest WalMart Neighborhood Market did, in fact, have BinaxNOW tests in stock just now. As I surmised, there were indeed behind the pharmacy counter and could be purchased by request. 2 box limit per customer -- but that's four tests per trip. Going to CVS for the FreeFlow tests limited me to two tests per trip.

Our WalMarts, and Neighborhood Markets, and Walgreens ... all those places did have dozens of BinaxNOW tests on floor display all through the fall. It wasn't until the weekend of December 17-18 that they vanished from the shelves. I was actually at our local Walgreens on Thursday, December 16th looking at a big display of BinaxNOW tests. There were so many ... I told myself "Meh, they'll have plenty later!" and so just bought one box   :wall:
I bought some of those in NO on Canal St. right around that time. Sorry dude. 

 
I've been reading a long, dense Medium piece about the pandemic response in America over the past year. There's a lot of detail in it with tons of supporting links. It answers a lot of "why" questions, especially about current (un)availability of NPI tools for the American on the ground.

Two excerpts, neither of which I realized happened:

In early June, 2021, when CDC announced that vaccinated people without symptoms should not be tested, it led to a collapse in demand for antigen tests. This prompted Abbott, the primary manufacturer at that point, to destroy millions of unused tests and lay off thousands of workers. The White House has also been lobbied at various points by testing experts who asked the federal government to order more tests, but they were rebuffed. Administration officials did not want to request more money for testing from Congress, and also believed that most people in the parts of the US hit the hardest by covid (largely the South, at that point) would not want to use tests.
:eek:
 

US mask manufacturers have lobbied the White House for the entirety of the Biden administration to use federal resources to buy N95s for the general population, and say that they are capable of producing hundreds of millions per month. Their attempts have been ignored.
:sadbanana:

 
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I've been reading a long, dense Medium piece about the pandemic response in America over the past year. There's a lot of detail in it with tons of supporting links. It answers a lot of "why" questions, especially about current (un)availability of NPI tools for the American on the ground.

Two excerpts, neither of which I realized happened:

:eek:
 

:sadbanana:
You could lead a horse to water but you apparently can't make them wear a mask. At least in Arizona and many other parts of the country.

 
I heard last week that SC has received something like $3B in Federal aid toward education during COVID. I'm not sure where it went but it hasn't gone to the teachers, it hasn't gone into new air handling systems although at the beginning of the year they promised they were installing them. It hasn't gone into new virtual programs


https://www.google.com/amp/s/abc13.com/amp/community-impact-newspaper-congress-federal-stimulus-money-19-billion-texas-schools-public-education/10515661/

The second and third rounds of ESSER funding, amounting respectively to $5.5 billion and $12.4 billion, have not yet been distributed to Texas public school districts. Morath said this is because the Legislature is awaiting guidance from the federal government on certain conditions tied to the funding.

Almost a year since the above article and I haven't heard of the funds being released yet. 

Some states aren't releasing the federal funds to schools for political reasons and hoping to keep the money for other uses.

 
AAABatteries said:
I'm hopeful that in 5 years when can work out both the issues with virtual classrooms but also the impacts to social skills.   More virtual means less teachers needed and more TAs.  Let's get our most gifted teachers in front of the most students possible.  We should consider in person students and remote teachers.
 A subject for another thread, but I'm highly skeptical assigning more students to the best teachers will lead to this suggested outcome. Part of what makes these teachers 'the best' is what they provide in one-on-one and small group settings. Such an environment ceases to exist if given more students. 

 
We just published another peer reviewed paper on long COVID.  To be clear, I am not an author but I am on the board of the company behind this research.

PR

Persistence of SARS CoV-2 S1 Protein in CD16+ Monocytes in Post-Acute Sequelae of COVID-19 (PASC) up to 15 Months Post-Infection

If you or a family member are suffering from this nasty affliction, PM me.  We have treated 1000s of patients and know more about this condition than any group in the world.


Very interesting and hopefully leads to a treatment.  I know a few long-haulers.

I don't see where vaccination was part of the control here -- any studies forthcoming on the prevalence of long-haul as it relates to vaccination status?

 
Here's the current hospital bed capacity in the 5 NYC boroughs and elective surgeries have NOT been canceled.

BK: 15%

SI: 16%

QN: 21%

MN: 20%

BX: 24%

 
Very interesting and hopefully leads to a treatment.  I know a few long-haulers.

I don't see where vaccination was part of the control here -- any studies forthcoming on the prevalence of long-haul as it relates to vaccination status?


We have treated many people who have never had COVID but who developed long COVID after vaccination.   To be clear, this is a rare occurrence and not in any way an argument against vaccines.  I will ask the question but I believe the answer to your question is that long COVID isn't influenced by tax status.

 
We have treated many people who have never had COVID but who developed long COVID after vaccination.   To be clear, this is a rare occurrence and not in any way an argument against vaccines.  I will ask the question but I believe the answer to your question is that long COVID isn't influenced by tax status.


I found this abstract as it relates to the S1 protein and severe disease from COVID (rather than long-haul).  Pretty interesting that it seems this piece of the spike protein floating around is likely to be the cause of severity and long-covid (potentially).  Perhaps the next mRNA vaccines need to take that into account -- thought that may impact effectiveness.

https://pubmed.ncbi.nlm.nih.gov/33838638/

Abstract

The imbalance of the renin-angiotensin system is currently considered as a potentially important factor of the pathogenesis of COVID-19 disease. It has been shown previously in the murine model, that the expression of angiotensin-converting enzyme 2 (ACE2) on the cell surface is downregulated in response to the infection by SARS-CoV virus or recombinant spike protein (S protein) alone. In the case of natural infection, circulation of the S protein in a soluble form is unlikely. However, in SARS-CoV-2, a large fraction of S protein trimers is pre-processed during virion morphogenesis due to the presence of furin protease cleavage site between the S1 and S2 subunits. Therefore, S protein transition into the fusion conformation may be accompanied by the separation of the S1 subunits carrying the receptor-binding domains from the membrane-bound S2 subunits. The fate of the S1 particles shed due to the spontaneous "firing" of some S protein trimers exposed on the virions and on the surface of infected cells has been never investigated. We hypothesize that the soluble S1 subunits of the SARS-CoV-2 S protein shed from the infected cells and from the virions in vivo may bind to the ACE2 and downregulate cell surface expression of this protein. The decrease in the ACE2 activity on the background of constant or increased ACE activity in the lungs may lead to the prevalence of angiotensin II effects over those of angiotensin (1-7), thus promoting thrombosis, inflammation, and pulmonary damage. This hypothesis also suggests the association between less pronounced shedding of the S1 particles reported for the S protein carrying the D614G mutation (vs. the wild type D614 protein), and lack of increased severity of the COVID-19 infection caused by the mutant (D614G) SARS-CoV-2 strain, despite its higher infectivity and higher in vivo viral load.

 
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Here's the current hospital bed capacity in the 5 NYC boroughs and elective surgeries have NOT been canceled.

BK: 15%

SI: 16%

QN: 21%

MN: 20%

BX: 24%


White House posted a graph as it relates to NYC: 

3,000+ cases per 100,000 unvaccinated. 

500 cases per 100,000 if vaccinated. 

80 hospitalizations per 100,000 people unvaccinated vs less than 10 hospitalizations per 100,000 people if vaccinated.  

 
I found this abstract as it relates to the S1 protein and severe disease from COVID (rather than long-haul).  Pretty interesting that it seems this piece of the spike protein floating around is likely to be the cause of severity and long-covid (potentially).
@chet , are you able to get questions answered about the study? Like, are there people you could shoot off a quick email to who you could ask something like "I read the study and I want to make sure I understand the findings -- is [simplification of a point the abstract] about right?"

The study you linked references monocytes, which is the class of white-blood cells that can turn to macrophages during immune response and literally "eat" chunks of viral protein from "defeated", busted-open virions. In normal immune reaction, the monocytes-turned-macrophages form a mini-cyst around the offending protein then absorb it into the cytoplasm over time -- essentially cellular "digestion".

Did the study find that -- in layman's terms and heavily bowdlerized -- that the monocytes are having cellular "indigestion"? That the loose chunks of viral protein are getting captured but not getting "fully digested" by the monocytes? And this allows the viral proteins to hang around and to prolong and/or "over-excite" the overall immune response, the manifestation of which is long COVID?

 
We have treated many people who have never had COVID but who developed long COVID after vaccination.   To be clear, this is a rare occurrence and not in any way an argument against vaccines.  I will ask the question but I believe the answer to your question is that long COVID isn't influenced by tax status.
I think the question meant vax status for those that had Covid and then long Covid. Not long Covid caused by the vax. That last part can't even be possible can it? 

 
I think the question meant vax status for those that had Covid and then long Covid. Not long Covid caused by the vax. That last part can't even be possible can it? 


Correct on what I am asking -- what is the prevalence of breakthrough cases causing long-covid versus unvaccinated cases causing long covid.

However, based on what Chet and these articles say, it seems possible long covid could result from a vaccine, if part of the spike protein (which is what the vaccines cause your body to produce via mRNA) failing to be properly absorbed by the body is what causes the inflammation.  

 
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I think the question meant vax status for those that had Covid and then long Covid. Not long Covid caused by the vax. That last part can't even be possible can it? 
I wouldn't call it "long COVID" ... but yeah, that would be a rare, faulty immune reaction to the "target practice" spike proteins elicited by mRNA vaccines. If I'm following correctly the paper chet linked ... they're finding that in people with long COVID, the monocytes aren't completely cleaning up the loose protein chunks from the "spent" virions.

But this can happen with any major immune reaction. People don't call them "long flu", "long meningitis", "long mononucleosis", "long RSV", etc. ... but they absolutely exist.

Both my kids had RSV as infants, which is very common. My daughter skated through, but my son had what we could call "long RSV" for over a year afterwards. We used this little guy to give him albuterol treatments for a good year and a half after he cleared the RSV infection.
 

 
Based on the UK and South Africa, we should peak in the US sometime late next week, and hopefully back down to fall numbers about 4 weeks after that . . . . caveat being the states yet to get hit with Omicron still have to go through it. 

Get vaxxed and/or boosted in the meantime to keep this at bay and get ready to roll up sleeves in the spring to ensure no resurgence this summer a la Delta (and maybe another shot right before Thanksgiving 2022 to really pound this thing into the ground going forward).

 
Based on the UK and South Africa, we should peak in the US sometime late next week, and hopefully back down to fall numbers about 4 weeks after that . . . . caveat being the states yet to get hit with Omicron still have to go through it. 

Get vaxxed and/or boosted in the meantime to keep this at bay and get ready to roll up sleeves in the spring to ensure no resurgence this summer a la Delta (and maybe another shot right before Thanksgiving 2022 to really pound this thing into the ground going forward).
0% chance I get a booster until fall at the earliest.

 
Nathan R. Jessep said:
nothing earth shattering, but interesting info I thought...

New (Pre-print, lab) study: COVID Loses 50% Of Its Ability To Infect After Ten Seconds In The Air

A new study (here's a link) shows that COVID-19 quickly loses its ability to infect people seconds after it becomes airborne. Researchers with the University of Bristol's Aerosol Research Center found that the virus loses about 50% of its ability to infect within ten seconds in a typical office environment.

Within 20 minutes of becoming airborne, the virus loses 90% of its ability to infect people.

"A decrease in infectivity to ∼10 % of the starting value was observable for SARS-CoV-2 over 20 minutes, with a large proportion of the loss occurring within the first 5 minutes after aerosolization," the researchers wrote in the pre-print study.

Because the virus spreads in tiny droplets expelled from the lungs, it quickly loses the ability to infect people when exposed to dry air. However, when the relative humidity is higher, the virus will keep its ability to infect people for more extended periods of time.

When they tested samples in the air with 90% humidity, which is the equivalent of a shower, they found that 52% of particles were still infectious after five minutes. However, by 20 minutes, just ten percent of the particles were still infectious.

The researchers also noted that the pH levels rapidly increase when the carbon dioxide in the environment decreases.

"People have been focused on poorly ventilated spaces and thinking about airborne transmission over meters or across a room. I'm not saying that doesn't happen, but I think still the greatest risk of exposure is when you're close to someone," Professor Jonathan Reid, director of the University of Bristol's Aerosol Research Centre and the study's lead author, said, according to The Guardian. "When you move further away, not only is the aerosol diluted down, there's also less infectious virus because the virus has lost infectivity [as a result of time]."


Typical air circulation systems blow air from above. 

What if modern air-systems created an updraft environment where intakes were at the top of a room pulling air (and particulate) upward, and climate-adjusted air was introduced lower? I realize this is a pipe dream currently and would involve significant changes to building construction... but there could be "hacks" to help create this type of environment in the meantime. 

 
Typical air circulation systems blow air from above. 

What if modern air-systems created an updraft environment where intakes were at the top of a room pulling air (and particulate) upward, and climate-adjusted air was introduced lower? I realize this is a pipe dream currently and would involve significant changes to building construction... but there could be "hacks" to help create this type of environment in the meantime. 
Calling @GroveDiesel to the white courtesy phone ...

There are heating systems that work like you propose, but I don't know if they're common in the U.S. Maybe in states that get truly cold like Alaska and the areas of the Midwest bordering Canada.

For an AC system, your proposal would be running against the tendency of warm air to rise and cold air to sink. Air is a fluid, though -- if you need to pump it "uphill", your can throw cash and energy at the problem and make it happen.

 
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