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***OFFICIAL CYDY/Leronlimab Thread*** (1 Viewer)

So supposed that W dude came out of the woodwork to protect me when I bought 100k shares.  And 20+ for my wife.  At the dollar range.  I got no PMs of him expressing his concern.  There were a few other FBG's involved.  Rude stepped in and it stopped.  

I never asked for advice and just stated my position.

Now when it gained did W, say sorry dude, I called that wrong.  I'm in the info and you got lucky, cash out now.  No.

He doesn't care about FBGs.  That is how a fbg in the know without an agenda would act.

I don't know his angle but it's not virtuous.  It just might be attention.

If me and chet or clayton or capella were on different sides of this stuff.  We would talk one on one and try to figure out what puts us both best.  None of that happening here.

Just my 2 cents.

 
Golf Guy 69 said:
So supposed that W dude came out of the woodwork to protect me when I bought 100k shares.  And 20+ for my wife.  At the dollar range.  I got no PMs of him expressing his concern.  There were a few other FBG's involved.  Rude stepped in and it stopped.  

I never asked for advice and just stated my position.

Now when it gained did W, say sorry dude, I called that wrong.  I'm in the info and you got lucky, cash out now.  No.

He doesn't care about FBGs.  That is how a fbg in the know without an agenda would act.

I don't know his angle but it's not virtuous.  It just might be attention.

If me and chet or clayton or capella were on different sides of this stuff.  We would talk one on one and try to figure out what puts us both best.  None of that happening here.

Just my 2 cents.
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^^ Definitely one of the best dudes here. 

 
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Don Hutson said:
I agree.  And if you look at my posts, I've been trying to figure out if the treatment arm having less SAEs than the placebo arm is indicative of efficacy.  These scientists aren't being forthright.  We know leronlimab has zero SAEs.  Placebos cause zero SAEs.  So all of the SAEs are from Covid.  The treatment arm having significantly less SAEs than the placebo arm is evidence of efficacy.  Scientists seem preprogrammed to say not necessarily but without a counter reason.
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I think "evidence" is the wrong word, and I think that's where scientists get hung-up in this discussion (especially when they only have partial context like Golf Guy's daughter).  They are so used to dealing with science and the FDA and needing real hard evidence to draw a conclusion. 

But we're not trying to draw a conclusion based on it.  We're trying to use it to give us a tip when essentially gambling on the results of the study.  Obviously the FDA wouldn't even blink at SAE numbers in a safety study when deciding whether or not a drug is effective enough to approve it.  But that is a very different context than what we're looking for, which is essentially if it might be a tip-off that the efficacy results are good.

It's like if I told you that we could gamble on a Titans game that has already happened but we can't see the outcome of.  We can't see the final score before we place our wager but we can see that Derrick Henry rushed for 280 yards and Ryan Tannehill only threw 8 passes.  That's not proof that the Titans won the game, but it means if we're going to gamble on who won the game the Titans would probably be a pretty good pick.

 
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FreeBaGeL said:
I think "evidence" is the wrong word, and I think that's where scientists get hung-up in this discussion (especially when they only have partial context like Golf Guy's daughter).  They are so used to dealing with science and the FDA and needing real hard evidence to draw a conclusion. 

But we're not trying to draw a conclusion based on it.  We're trying to use it to give us a tip when essentially gambling on the results of the study.  Obviously the FDA wouldn't even blink at SAE numbers in a safety study when deciding whether or not a drug is effective enough to approve it.  But that is a very different context than what we're looking for, which is essentially if it might be a tip-off that the efficacy results are good.

It's like if I told you that I knew the results of a Titans game and you didn't and you could gamble on the outcome.  I won't tell you who wins but I'll tell you that Derrick Henry rushed for 280 yards and Ryan Tannehill only threw 8 passes.  That's not proof that the Titans won the game, but it means if you're going to gamble on who won the game the Titans would probably be a pretty good pick.
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Right.  It’s not evidence scientifically, but it’s suggestive.

i think though if you did a detailed analysis on the Specific SAE’s it could serve as evidence of efficacy, but at that point you’ll basically be doing the primary endpoint analysis.

 
Don Hutson said:
https://www.proactiveinvestors.com/companies/news/924762/cytodyn-showcases-its-patient-safety-data-from-its-phase-2-coronavirus-trial-924762.html
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Just watched this a few times and it does seem like the death is in the treatment arm, but I really don't think it has anything to do with COVID. 

He said something like "people bashing the stock said there's a death 33 days after the 2nd injection...can get hit by a car." The mild to moderate study study range was only 14 days, so this is well past that date. Granted if someone deteriorated due to COVID it could take that long. 

Mostly it's just his body language for me. He's still super upbeat, but it seems genuine. He doesn't stumble with his words, but it doesn't sound rehearsed. If the death was caused by COVID despite being on LL I don't see a hint of sadness from NP. He's either genuine or a psychopath considering how slick he would have to be to pull off this front. 

Any other amateur body language experts out there?

Also he did state that next week the FDA will take a look at the S/C study so next week could potentially be a huge one.

 
adonis said:
Right.  It’s not evidence scientifically, but it’s suggestive.

i think though if you did a detailed analysis on the Specific SAE’s it could serve as evidence of efficacy, but at that point you’ll basically be doing the primary endpoint analysis.
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Correct.  If in the S/C trial the safety side comes back with 40/50 SAE's in the Placebo and 20/100 in the drug arm, I would be feeling really good.  Most scientists would say it doesn't prove anything, but I think I would be doubling my stock.

 
Charlie Harper said:
Just watched this a few times and it does seem like the death is in the treatment arm, but I really don't think it has anything to do with COVID. 

He said something like "people bashing the stock said there's a death 33 days after the 2nd injection...can get hit by a car." The mild to moderate study study range was only 14 days, so this is well past that date. Granted if someone deteriorated due to COVID it could take that long. 

Mostly it's just his body language for me. He's still super upbeat, but it seems genuine. He doesn't stumble with his words, but it doesn't sound rehearsed. If the death was caused by COVID despite being on LL I don't see a hint of sadness from NP. He's either genuine or a psychopath considering how slick he would have to be to pull off this front. 

Any other amateur body language experts out there?

Also he did state that next week the FDA will take a look at the S/C study so next week could potentially be a huge one.
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My uncle said the same thing when I sent him the video. Said if he’s lying he’s one of the best liars he’s ever seen. 

 
Golf Guy 69 said:
She thinks having 16 secondary outcomes is going to take a while to analyze but they all ready know if they hit their primary or not. Don't know why they are not telling that info. 
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And be accused of dribbling out the results?

I don't think that's how it's done. 

 
Charlie Harper said:
 A total of 19 serious adverse events (SAEs) were reported during the study. Eleven (11) SAEs were reported in 6 patients (6/28; 21.4%) receiving placebo compared to eight (8) SAEs in 5 patients (5/56; 8.9%) receiving leronlimab. None of the SAEs in the leronlimab arm were deemed related to study drug administration by the investigators. Of the 84 patients treated, one patient died 33 days after enrollment due to an event unrelated to leronlimab.
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That's the text from the press release of the Safety where the death is first mentioned. I do remember now someone bringing this up when it was first released. 

The fact that they didn't outright point out it was in the placebo group means it was in the treatment arm. Now the question is...did that patient progress to severe and eventual death due to COVID or was it something else? 33 days after enrollment (safe to assume symptomatic).

COVID disease progression.

Now this is data from early on, but average day of death per the article is 18.5 days. Average release from hospital is 22 days. So a death 33 days after enrollment would likely be out of the hospital.

So it seems likely that the patient left the hospital and got hit by a car.

#notselling

 
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If that patient really did end up getting hit by a car it’s going to be one of the funnier tragic events to ever happen. 

 
Golf Guy 69 said:
So supposed that W dude came out of the woodwork to protect me when I bought 100k shares.  And 20+ for my wife.  At the dollar range.  I got no PMs of him expressing his concern.  There were a few other FBG's involved.  Rude stepped in and it stopped.  

I never asked for advice and just stated my position.

Now when it gained did W, say sorry dude, I called that wrong.  I'm in the info and you got lucky, cash out now.  No.

He doesn't care about FBGs.  That is how a fbg in the know without an agenda would act.

I don't know his angle but it's not virtuous.  It just might be attention.

If me and chet or clayton or capella were on different sides of this stuff.  We would talk one on one and try to figure out what puts us both best.  None of that happening here.

Just my 2 cents.
Click to expand...
I was with you until Capella

 
Golf Guy 69 said:
Show proof of everything he said that you are saying is the same.  
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What?  Whyatt has provided us a ton of insight.  Your daughter's input has been exactly the same as Whyatt's opinion.  I am going to work on the assumption that your daughter and Whyatt know more than us.  I am working on the assumption that you know nothing.

 
Don Hutson said:
What?  Whyatt has provided us a ton of insight.  Your daughter's input has been exactly the same as Whyatt's opinion.  I am going to work on the assumption that your daughter and Whyatt know more than us.  I am working on the assumption that you know nothing.
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You asked me to be specific, I did.  You won't.  What do u want?  You won't back up your statement and now it's my fault.

 
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So, based on reading this thread, I’ve done some research on CYDY. To summarize my thoughts, I find the Culper report more on point than not, and that overall company raises multiple red flags. l‘ve investigated options to short the stock, but have not made this move yet.

I work in the industry, and while I’m not an expert in HIV treatments/preventions or cancer, I have more insight than most. For example I know HIV is a crowded field with big Pharma working diligently on improved options for patients with infinitely more resources that CYDY. Merck’s big cancer drug Keytruda has dozens of clinical trials ongoing, is it clear where CYDY might fit as a cancer treatment?

I realize I’m raising an unpopular perspective, but I offer my opinion to help this group make better informed investment decisions. 

 
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