Likely a couple of reasons.
The prime directive in this offseason for Eli was to throw less INTs. They brought in a whole new offense. Something Eli has never run before, and asked him to completely change his footwork too. Last year the number of INTs that Eli threw while targeting Rueben Randle was off the charts high. Randle isn't a consistent route runner, and if you are looking off a safety until the last second you are more throwing to a spot rather than a player. Randle made Eli look foolish last year on a number of occasions. This year, Eli likely feels he needs to see it before he'll throw it. Aaron Rodgers talks about it all the time on his radio show. You have to trust a guy to be in the right spot. Everyone of Eli's targets at the moment is either new, or untrustworthy.
This is a temporary problem. Likely to be solved next year when he's got Cruz back, and a full season with OBJ and Donnell as his main targets. He'll also be a lot more comfortable with this new offense etc.
Again, all good trains of thought... and partially I agree.
But how could he not trust ODB? To be honest, ODB is making Eli look good. plucking balls that most WRs would drop. running routes most rookies cant run.... Randle, while not a great WR, is a decent WR2 and shouldnt be seen as a hindrance to Eli as such.
His INTs are wayyyyyyy down, in that respect he looks very good. His oline isnt doing his favors, also agreed. But he just does NOT look comfortable, and often looks lost. We see guys like brady, who despite being thrown in a den w rookies and scrubs, rarely, id ever, looks that way.
Eli is not Brady. Sure. But he's a 2 time SB winner, and as such, should look much better than he does right now