There are a lot of chance occurrences which makes it a probability game. To me, fantasy football is a little like blackjack. You've got the people who are counting cards, the people who are simply playing by the chart, and then the fools who play by their gut. The probabilities vary by house rules and number of decks, but for this example let's say the card counter has a 51% chance of winning, the chart player is at 48%, and the gut player is like 40%. In the long run the card counter is the only one that will make money, but in the course of a single hour it is very possible the guy hitting on 17 when the dealer is showing a 6 is actually winning and the guy counting cards is losing. Same thing happens with fantasy football in any given 16 game season. Nobody could predict Rodgers' injury or the total collapse of the Oakland offense. Before Ware's injury nobody could've predicted Hunt's 91% snap share. Nobody could've predicted Kamara's breakout with Ingram around. I know every player has a cult following, but these people who blindly predict breakouts are akin to a broken clock being right twice a day. If you search their history, I'm sure they've said the same thing about many flame outs. Just check the "bet your house" thread. Those players are the gut players in blackjack. They'll get lucky just enough times to think their gut feelings are actually some sort of crystal ball.
But the point is, you can be the card counter if you follow offensive line signings, offense coordinators, injuries, and advanced statistics. Some unpredictable things will still happen, but so will some of the predictable things. However, some of them are only predictable if you are looking closely.