***OFFICIAL CYDY/Leronlimab Thread*** (3 Viewers)

[Bluto Blutarsky]

Let’s get Golf Daughter registered here

 

[Don Hutson]

She said she they did a cancer study on brain cancer. They injected the drug into the brain and it killed the cancer but also killed the person. So it was a good drug for cancer but not safe at all

But we know leronlimab is completely safe.  800 people have taken it for HIV for years with zero SAEs.  There were a lot of SAEs in the M2M trial.  Those SAEs must have been caused by Covid.  The treatment arm having less SAEs would imply efficacy.

 

[Chaz McNulty]

She said she they did a cancer study on brain cancer. They injected the drug into the brain and it killed the cancer but also killed the person. So it was a good drug for cancer but not safe at all

Was it dissinfectant? And was Trump running the surgery?

 

[Zegras11]

Reply from my daughter.  One reason to stall is if they are waiting to get listed on NASDAQ.  This could be because good or bad results.  To get that protection before releasing info so the stock can not be manipulated as easy.

this was my first thought also.

 

[Golf Guy 69]

There is no direct correlation between SAE numbers.  They need to be studied on a case by case basis.  SAE can have nothing to do with the drug.

 

[Don Hutson]

There is no direct correlation between SAE numbers.  They need to be studied on a case by case basis.  SAE can have nothing to do with the drug.

Both sides of the trial have a lot of SAEs.  The SAEs being caused by Covid is the only explanation.  

 

[Golf Guy 69]

But we know leronlimab is completely safe.  800 people have taken it for HIV for years with zero SAEs.  There were a lot of SAEs in the M2M trial.  Those SAEs must have been caused by Covid.  The treatment arm having less SAEs would imply efficacy.

No on a whole.  Needs to be determined case by case to get true numbers.  SAE can be someone on LL has a heart attack while taking LL when LL had nothing to do with the attack.

 

[Bob Sacamano]

Buncha slow, old fogies around here these days.

 

[Don Hutson]

No on a whole.  Needs to be determined case by case to get true numbers.  SAE can be someone on LL has a heart attack while taking LL when LL had nothing to do with the attack.

It's a 14 day trial.  Each arm having 5 or 8 SAEs is not random stuff.  It has to be caused by Covid.  No other explanation makes sense.

 

[Golf Guy 69]

There is no direct correlation between SAE numbers.  They need to be studied on a case by case basis.  SAE can have nothing to do with the drug.

SAE can also have nothing to do with Covid.

 

[Chaz McNulty]

Both sides of the trial have a lot of SAEs.  The SAEs being caused by Covid is the only explanation.  

Most likely.  Placebo's cause insignificant harm, and LL has been shown to be extremely safe.  Most of the SAE's in this trial are likely from Covid.

 

[Golf Guy 69]

It's a 28 day trial.  Each arm having 5 or 8 SAEs is not random stuff.  It has to be caused by Covid.  No other explanation makes sense.

In a small sample size, you just cant say this.  More often than not you may be right.  This is science and results need to be scrutinized.

 

[Chaz McNulty]

SAE can also have nothing to do with Covid.

That's true.  You could get hit by a car or have something else happen to you.  But if the drug and the placebo are completely safe, then there is a good chance that the SAE is being caused by Covid.

 

[Don Hutson]

In a small sample size, you just cant say this.  More often than not you may be right.  This is science and results need to be scrutinized.

84 people.  14 days.  13 SAEs and they aren't Covid related?

 

[Golf Guy 69]

Most likely.  Placebo's cause insignificant harm, and LL has been shown to be extremely safe.  Most of the SAE's in this trial are likely from Covid.

Is it a good sign? Yes.  Is it empirical evidence.  No.

 

[Golf Guy 69]

84 people.  14 days.  13 SAEs and they aren't Covid related?

We will find out.  How you want drug studies to work isn't how they work.

 

[Golf Guy 69]

That's true.  You could get hit by a car or have something else happen to you.  But if the drug and the placebo are completely safe, then there is a good chance that the SAE is being caused by Covid.

I don't disagree but it means squat to the FDA.

 

[Chaz McNulty]

Is it a good sign? Yes.  Is it empirical evidence.  No.

Of course.  It has yet to be determined.  People are just speculating.  This was the only study done on Covid so far, where the drug beat the placebo in SAE count.

 

[Golf Guy 69]

One last thing she said.  Old drugs are still doing good stuff all the time.  Being old has no relevance.

 

[Chaz McNulty]

One last thing she said.  Old drugs are still doing good stuff all the time.  Being old has no relevance.

Thanks.  I'll tell my wife.

 

[Capella]

I wish I knew brother. 

You selling any Monday?

 

[Golf Guy 69]

Text from wife.

She's on the clinical trials.gov. She's reading about their M2M study 

 

[Golf Guy 69]

You selling any Monday?

Is it hitting 7?

Or going to 4?

This is no longer a hold only for me.  I think it's going rollercoaster no matter what.  I will always not put 30k shares into play but try to sell and buy with the rest.

 

[Golf Guy 69]

Most likely.  Placebo's cause insignificant harm, and LL has been shown to be extremely safe.  Most of the SAE's in this trial are likely from Covid.

I talked with her on the phone about this.  It's a good marker but she just wont make the leap you guys are because she knows it is not directly related.

 

[Golf Guy 69]

Text from wife.

She's on the clinical trials.gov. She's reading about their M2M study 

Their primary outcome measure was a decrease in their symptoms score. Then they had 12 secondary outcomes and 4 exploratory outcomes. She said they are throwing darts at everything. 

 

[Don Hutson]

I talked with her on the phone about this.  It's a good marker but she just make the leap you guys are because she knows it is not directly related.

It's not necessarily directly related but since the placebo cannot cause SAEs directly and leronlimab does not cause SAEs it is reasonable to assume that all SAEs were caused by Covid?  And since the treatment arm had less SAEs than the placebo arm, leronlimab is the reason?

 

[Charlie Harper]

Their primary outcome measure was a decrease in their symptoms score. Then they had 12 secondary outcomes and 4 exploratory outcomes. She said they are throwing darts at everything. 

So is a delay in top line results still worrisome?

 

[Golf Guy 69]

So is a delay in top line results still worrisome?

The request itself is worrisome.  Too broad IHO.  

 

[Charlie Harper]

It's not necessarily directly related but since the placebo cannot cause SAEs directly and leronlimab does not cause SAEs it is reasonable to assume that all SAEs were caused by Covid?  And since the treatment arm had less SAEs than the placebo arm, leronlimab is the reason?

 Correlation does not equal causation.

Statistics 101.

But it's definitely a good sign.

 

[Golf Guy 69]

My wife who has 20k shares is still not selling but there are a lot of fleas with this trial.

 

[adonis]

The request itself is worrisome.  Too broad IHO.  

Doesn’t make much sense as the disease isn’t well known nor the mechanism for how the drug would affect it.  If you’re doing a study, why not introduce many measures to get a good idea of how your drug affects people as it pertains to Covid?  These parameters were set early March when even less was known.  They were set in partnership with the FDA.

 

[Golf Guy 69]

She said a person on one of her studies got in a car accident and was hospitalized that was a SAE. She had one in hospital with appendicitis that was a SAE. One was in the hospital or a gall bladder surgery that was a SAE. None of them were drug related. 

They can not say it was Covid 

 

[Golf Guy 69]

She thinks having 16 secondary outcomes is going to take a while to analyze but they all ready know if they hit their primary or not. Don't know why they are not telling that info. 

 

[Don Hutson]

She said a person on one of her studies got in a car accident and was hospitalized that was a SAE. She had one in hospital with appendicitis that was a SAE. One was in the hospital or a gall bladder surgery that was a SAE. None of them were drug related. 

They can not say it was Covid 

There is a total of 19 SAEs.  The study had 84 patients over 14 days.  It is probably all Covid.  Maybe 1 is not.  But probably all are Covid.

 

[Golf Guy 69]

Doesn’t make much sense as the disease isn’t well known nor the mechanism for how the drug would affect it.  If you’re doing a study, why not introduce many measures to get a good idea of how your drug affects people as it pertains to Covid?  These parameters were set early March when even less was known.  They were set in partnership with the FDA.

Re didn't say it was bad to have so many secondary causes. She thinks they are hoping to show it works on many different areas 

 

[BassNBrew]

But we know leronlimab is completely safe.  800 people have taken it for HIV for years with zero SAEs.  There were a lot of SAEs in the M2M trial.  Those SAEs must have been caused by Covid.  The treatment arm having less SAEs would imply efficacy.

Except for the one person who died who appartently was a Leronlimab patient.

 

[Charlie Harper]

She thinks having 16 secondary outcomes is going to take a while to analyze but they all ready know if they hit their primary or not. Don't know why they are not telling that info. 

I took a look at the Remdesivir study to get a comparison. In her opinion was the primary outcomes for Remdesivir "better" from a trial structure viewpoint? Does CYDY investigation outcomes differ that much?

 

[Capella]

She thinks having 16 secondary outcomes is going to take a while to analyze but they all ready know if they hit their primary or not. Don't know why they are not telling that info. 

They’ll get killed if they release just the primary and then nothing else imo. Would make sense to me to wait till you have it all. 

 

[Charlie Harper]

Except for the one person who died who appartently was a Leronlimab patient.

Where did you get this? Thought we didn't know what group the patient was in?

 

[Capella]

Except for the one person who died who appartently was a Leronlimab patient.

Who said that? 

 

[Golf Guy 69]

Okay I'm done.  Text to mb, mb to text.  Zero context.  I copy and pasted the questions and the responses for the direct ones.  There are no answers but maybe more insight.

 

[Capella]

Doesn’t make much sense as the disease isn’t well known nor the mechanism for how the drug would affect it.  If you’re doing a study, why not introduce many measures to get a good idea of how your drug affects people as it pertains to Covid?  These parameters were set early March when even less was known.  They were set in partnership with the FDA.

I agree with this. If there were ever a trial where you’d throw every dart it would be this one. 

 

[BassNBrew]

Except for the one person who died who appartently was a Leronlimab patient.

Where did you get this? Thought we didn't know what group the patient was in?

Process of elimination by omission.

 

[Capella]

She thinks having 16 secondary outcomes is going to take a while to analyze but they all ready know if they hit their primary or not. Don't know why they are not telling that info. 

Also releasing just part of this would lead to more skepticism. Where is the rest of the report? Must have been terrible if they just released a part of it? If you want the true stock pop you need to put it all out. Once people analyzed it, they would drag it down. 

 

[Capella]

Process of elimination by omission.

Nah

 

[BassNBrew]

Who said that? 

Of the 84 patients treated, one patient died 33 days after enrollment due to an event unrelated to leronlimab.

From the company website.

 

[Don Hutson]

Where did you get this? Thought we didn't know what group the patient was in?

I think Nader said the patient died 33 days after the trial started and they were in the treatment arm.  And then he said that a patient dying from a car accident would be considered as an SAE.  But he was talking theoretical.  Clearly, the patient died from Covid and was in the treatment arm.

 

[Golf Guy 69]

Process of elimination by omission.

But it may not be drug related, it may be.

 

[BassNBrew]

I think Nader said the patient died 33 days after the trial started and they were in the treatment arm.  And then he said that a patient dying from a car accident would be considered as an SAE.  But he was talking theoretical.  Clearly, the patient died from Covid and was in the treatment arm.

Yup.  Doesn't look good when your only patient who dies from a mild/moderate case of Covid was taking the cure.

 

[pecorino]

Buncha slow, old fogies around here these days.

Should be crickets and minor price movements until the efficacy report is published and/or the uplisting. Good for some day trading but not much to opine about.