Familiarity likely works in HOU's favor. Mind you, these stats are have a healthy Watt factored in but HOU has owned Bortles at home over the past two years.
In 2014 Bortles was 14 of 33 for for 117 yards, no TDs, no INTs. He was sacked 5 times and fumbled but JAC recovered the ball. JAC scored 17 points in this game.
In 2015 Bortles was 17 of 32 for 239 yards, no TDs, 2 INTs. He was sacked 8 times and fumbled twice, he lost one of them. JAC scored 6 points in this game.
Edit: Watt accounted for 3 sacks in each game. Bortles 100% has nightmares about Watt.
Bortles has never thrown a TD on the road vs. HOU. He's been much better at home (5 TDs) but still turns the ball over, fumbling at least once every game. Again, I know the sample size is small and this isn't the same HOU defense but it's clear HOU's DST has put up points at home vs. JAC in recent history. I think they need to be up for consideration for week 15, especially assuming Clowney and Joseph are back.