For single seasons, from 2000 to 2017, played RB, requiring Rushing Att >= 200, sorted by descending Weight also the number of seasons they had over 200 rushing attempts.
Le'Ron McClain 1 season
Brandon Jacobs 3 seasons
Jerome Bettis* 4 seasons
Ron Dayne 1 season
Eddie Lacy 2 seasons
LeGarrette Blount 2 season
Michael Bush 1 season
Duce Staley 1 season
Stacey Mack 1 season
Peyton Hillis 1 season
Jamal Lewis 8 seasons
Jonathan Stewart 3 seasons
LenDale White 2 seasons
Kevan Barlow 2 seasons
Jamal Anderson 1 season
Michael Turner 3 seasons
Eddie George 4 seasons
Shonn Greene 2 seasons
Maurice Smith 1 season
Beanie Wells 1 season
Tyrone Wheatley 1 season
Fred Taylor 6 seasons
Ronnie Brown 4 seasons
Troy Hambrick 1 season
Deuce McAllister 4 seasons
Antowain Smith 1 season
Mike Anderson 2 seasons
Stephen Davis 4 seasons
Jeremy Hill 3 seasons
LaMont Jordan 1 season
Mikel Leshoure 1 season
Latavius Murray 2 season
Carlos Hyde 2 seasons
Spencer Ware 1 season
Ezekial Elliot 2 seasons
Leonard Fournette 1 season
Marcel Shipp 1 season
Lamar Smith 1 season
Steven Jackson 8 seasons
Larry Johnson 2 seasons
Kevin Jones 1 season
Willis McGahee 5 seasons
Trent Richardson 1 season
Anthony Thomas 3 seasons
Arian Foster 4 seasons
Todd Gurley 3 season
Ricky Williams 5 seasons
Shaun Alexander 7 seasons
Le'Veon Bell 4 seasons
Isiah Crowell 1 season
Corey Dillon 5 seasons
CJ Anderson 1 season
Jordan Howard 2 seasons
David Johnson 1 season
Nick Goings 1 season
Alfred Morris 4 seasons
James Stewart 1 season
Chris Ivory 1 season
Doug Martin 2 seasons
Cedric Benson 4 seasons
Ladell Betts 1 season
DeShaun Foster 2 seasons
Marion Barber 3 seasons
Jay Ajayi 2 seasons
Matt Forte 9 seasons
Emmitt Smith* 4 seasons
LaDainian Tomlinson* 10 seasons
Joique Bell 1 season
Justin Fargas 2 seasons
Rudi Johnson 4 seasons
Thomas Jones 7 seasons
Ryan Mathews 2 seasons
Lamar Miller 3 seasons
DeMarco Murray 3 seasons
Adrian Peterson 8 seasons
Stevan Ridley 1 season
Andre Williams 1 season
Chris Brown 2 seasons
Ryan Grant 2 seasons
Michael Pittman 3 seasons
Vick Ballard 1 season
Ahman Green 6 seasons
Ricky Watters 1 season
Cadillac Williams 3 seasons
Zac Stacy 1 season
Domanick Williams 3 seasons
Melvin Gordon 2 seasons
Earnest Graham 1 season
William Green 1 season
BenJarvus Green-Ellis 3 seasons
Garrison Hearst 2 seasons
Travis Henry 4 seasons
Mark Ingram 3 seasons
Fred Jackson 3 seasons
Marshawn Lynch 8 seasons
Knowshon Moreno 2 seasons
Edgerrin James 7 seasons
Priest Holmes 3 seasons
Chester Taylor 1 season
James Allen 1 season
Frank Gore 12 seasons
Robert Smith 1 season
Michael Bennett 1 season
Marshall Faulk* 4 seasons
Joseph Addai 3 seasons
Julius Jones 2 seasons
Curtis Martin* 6 seasons
LeSean McCoy 8 seasons
Darren McFadden 3 seasons
Rashard Mendenhall 4 seasons
Kevin Smith 2 seasons
Alex Collins 1 season
DeAngelo Williams 4 seasons
Willie Parker 4 seasons
Kareem Hunt 1 season
Reuben Droughns 3 seasons
Devonta Freeman 2 seasons
Maurice Jones-Drew 4 seasons
Clinton Portis 6 seasons
Dominic Rhodes 1 season
Tiki Barber 6 seasons
Reggie Bush 3 seasons
Ronnie Hillman 1 season
Brian Westbrook 3 seasons
Jamaal Charles 4 seasons
Andre Ellington 1 season
Ahmad Bradshaw 2 seasons
Justin Forsett 1 season
Chris Johnson 6 seasons
Ray Rice 5 seasons
Steve Slaton 1 season
C.J. Spiller 2 seasons
Tatum Bell 1 season
Charlie Garner 2 seasons
Warrick Dunn 6 seasons
LINK
Some issues with this querry are players drafted before 2000 PFR does not have combine data for their weight. For example in the case of Emmitt Smith he was drafted at 210 lbs but he added weight after he entered the NFL. For Adrian Peterson I know his weight at the combine was 217 but he is listed at 220 by PFR there are likely other errors like this for the players drafted before 2000.
If someone wants to take this a step further and show the fantasy points generated by these players that would be relevant. 200 rushing attempts does not mean the player actually had a good season.
We may want to eliminate the players who only had one 200 or more rushing attempts in a season. There are a lot of these in the sample and I do not think they would meet the criteria of a "feature RB" for more than one season. A lot of these players got those carries because of injuries to other RB in the season that they got them.
I don't know about the rest of you but I would rather have the fantasy careers of the players below 215 lbs from this sample than the ones above 215 lbs but to each their own. There are certainly a lot of very good RB below 215 lbs on this list.