ok lets break this down a bit as I am unsure we are looking at 11 changes today as some seem to be suggesting with a full B team,
1) Dest has a yellow, came off limping, and was overall poor against Wales. He likely would have been changed out today no matter what the group state was.
2) Weston has a yellow, came off limping and does not in any way look fit to go 90. There is a smaller chance that he would not have started any way today.
3) Every one wants to see Reyna play, so if he starts, either Weah or Pulisic or Musah will not start. If Gio is healthy, these will be even trades.
4) Jesus was very likely to start today no matter what. Sargent hardly made anyone scream he has to start against England with his non play against Wales.
After this, the only other possible change due to game state is Ream.
I would be shocked to see more than 6 changes but with GGG I guess we need to wait a few more hours to be sure.