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Stock Thread (7 Viewers)
- Thread starter St. Louis Bob
- Start date
Capella
Footballguy
Look I don’t know anything about this and I’m just reading homer message boards but it seems that the safety is a tremendously big deal and the data takes time to evaluate. And there’s this:This doesn’t seem like a story you lead with if you have more impressive results on the efficacy. This is one of those things you finish with after you prove it does what you hope it does.
Remdesivir SAE's 21.1% for patients receiving Remdesivir vs 27% placebo.
Leronlimab SAE's 8.9% for patients receiving Leronlimab vs 21.4% placebo.
BassNBrew
Footballguy
Up 33% in Germany.
https://www.boerse-berlin.com/index.php/Shares?isin=US23283M1018
This would put us right back at $10. Here's the exit point for those kicking themselves over last time.
https://www.boerse-berlin.com/index.php/Shares?isin=US23283M1018
This would put us right back at $10. Here's the exit point for those kicking themselves over last time.
adonis
Footballguy
First, do no harm. - check
Second, help the patient. - pending
a 50% reduction in SAEs is meaningful, don’t get me wrong. Based on the clinical trial setup, that may actually be the news as something like that was the main thing being measured.
hmmmm
Second, help the patient. - pending
a 50% reduction in SAEs is meaningful, don’t get me wrong. Based on the clinical trial setup, that may actually be the news as something like that was the main thing being measured.
hmmmm
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fred_1_15301
Footballguy
Which seems odd to me given that the comparator is a sugar pill. I doubt any of those SAEs in the placebo group are actually attributed to the actual placebo (at least I certainly hope note).
The Ref
Footballguy
The FDA looks for safety first, efficacy second. Though I will say that I thought safety had been established in prior trials so I’m not sure how needle-moving this is.This doesn’t seem like a story you lead with if you have more impressive results on the efficacy. This is one of those things you finish with after you prove it does what you hope it does.
![[icon]](/data/avatars/m/5/5167.jpg?1660313464){kind=avatar}
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Insoxicated
adonis
Footballguy
I’m traveling but if someone goes back and looks at the trial parameters, wasn’t there an overall score they were measuring that totaled the severity of reactions or adverse events?
BassNBrew
Footballguy
But the bulk of the SAEs could have occurred in a few placebo patients. This study is pretty dang small to draw many conclusions. It would be like cutting your first round draft pick for a FA after week one. I was really hoping for some comment on the efficacy.
cosjobs
Footballguy
BassNBrew
Footballguy
I-ROK
Footballguy
I don’t know much about this either, just skeptical. It seems like a big deal, but not the news you’d lead with if you’ve got a magic bullet thy kills anything
Capella
Footballguy
Capella
Footballguy
I’m guessing they don’t have all the data analyzed yet and want to let everyone know it’s safe or option #2 is that it’s a dud and they are delaying that news for now. I’m going with option 1 based off the fact that there is a clear difference in the adverse effects.
BassNBrew
Footballguy
It's in the ballpark SA. It's all time high at close was $8.77. We are basically at the prior decison point if our opening follows Germany. Many were selling yesterday to lock in profits. Many others will have the same decision today.
djmich
Footballguy
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Insoxicated
Search Results Currency Converter
6.85 Euro equals 7.83 United States Dollar
what kind of drunken calculator are you using?
BassNBrew
Footballguy
WTF did they do all weekend? It's not like there was a full slate of football games or even MLB to watch.
Caesar
Footballguy
So, Bass. Are you looking to sell and then buy back if there's a pullback? What are your exit and entry point targets if so?
adonis
Footballguy
They’re positive, but lacking sufficient context/detail to be really good. Details of this combined with efficacy would be great.
im sure it’s coming but I was hoping to have safety and efficacy today.
BassNBrew
Footballguy
BassNBrew
Footballguy
I'll be doing the same. I suspect there will be a sharp pullback and choppy trading today. I'm sure the shorts are primed to pounce.
adonis
Footballguy
It’s hard to put a story together about how you can reduce sae’s by half and not also have meaningful impact with efficacy. The reduction in SAE’s don’t just magically happen.
Capella
Footballguy
I don’t know anything about #### in hand monoxide but I’m not sure how the SAEs could be so dramatically lower if there isn’t efficacy. Jmo.
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I-ROK
Footballguy
I-ROK
Footballguy
A drug can’t be safe, but also not have any effect on a particular disease?
Tylenol is safe, but doesn’t do a thing for reflux
fantasycurse42
Footballguy Jr.
The portion of SAE in the placebo group is substantially higher, do you think that’s just a coincidence?
djmich
Footballguy
Jesus, this board is going to be unreadable.
They have the topline, they released the topline.
Topline indicates the drug does not harm the patient. I know you guys dont give a ####, but that is important.
As the scientists here have pointed out, that does not mean it helps. However, topline results indicate more than a 50% reduction in SAE's. Yes?
Detailed efficacy is to come. If you think they have the detailed efficacy results and they are ####ty so they are prolonging the chopping block a few days by not releasing them now then you certainly should exit today.
They have the topline, they released the topline.
Topline indicates the drug does not harm the patient. I know you guys dont give a ####, but that is important.
As the scientists here have pointed out, that does not mean it helps. However, topline results indicate more than a 50% reduction in SAE's. Yes?
Detailed efficacy is to come. If you think they have the detailed efficacy results and they are ####ty so they are prolonging the chopping block a few days by not releasing them now then you certainly should exit today.
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fantasycurse42
Footballguy Jr.
BassNBrew
Footballguy
Here's a chance to break out your skills...
Where do you think think it should trade at today?
Where do you think it will trade at?
cosjobs
Footballguy
I'm hoping there is weakness shown, as I would love to buy more.
But I am afraid $8 will be the closest we see to weakness today
To start, everyone knows my thinking related to this company.
This PR looks like spin to me. This isn’t the PR they were hopeful for a week ago. Realize that the death was almost certainly due to coronavirus.
Looks like no deaths in the placebo arm, so the unmet medical need angle for drug EUA is not there.
fred_1_15301
Footballguy
It's not a coincidence. SAEs are defined by events such as death, hospitalization, etc. Obviously a placebo isn't going to cause these types of events (there isn't toxicity associated with a sugar pill). Thus, the only explanation for the SAEs to actually be lower in the drug group is if the drug prevents these occurrences from happening. Good news but still need to see the efficacy results for confirmation.
cosjobs
Footballguy
I think it open around 8. I think it goes beyond, but many variables besides the stock's value can impact that, including but not limited to: press reaction, short sellers, FED printing money and many others.
These result warrant a minimum of a 20% bump and as crazy positive as the market has been to positive COVID news it could go significantly higher.
djmich
Footballguy
BassNBrew
Footballguy
Can you post a link to where you get your quotes. I noticed my source wasn't updating and google has not been my friend on this one.
cosjobs
Footballguy
cosjobs
Footballguy
Mine has not had an update ina while, either. Unsure of it as a source at this point>
https://www.boerse-berlin.com/index.php/Shares?isin=US23283M1018
Note disclaimer on their page:
OTC-QB and OTC-BB are US-American off-exchange trading platforms. The companies listed there are not subject to the regulations of an American exchange but have to fulfil disclosure obligations towards the American exchange supervisory body SEC. Both markets are therefore accepted as “recognized markets” for secondary listings.
Despite the transparency obligations on the home market it cannot be prevented in all cases that disreputable market participants try to influence trade in fraudulent ways. Regarding OTC-QB and OTC-BB Börse Berlin has made the experience that such influencing may not only take place at Börse Berlin alone, but also simultaneously at the American trading venue.
Golf Guy 69
Footballguy
As always, thanks for your views. If the death in the treatment group was due to Covid, won’t they need to disclose that?
The Ref
Footballguy
If you go to Yahoo Finance enter in 296.SG that will give you the 15 min delay price off the DAX.
It’s at 6.20 Euro at the moment or ~ $7.13 USD
so I’d say we probably aren’t rich today based off of this...... but
there have been several days where the DAX trots allong up 5-10-15% then in opens in the US and bang it’s up 25% and rises from there.
It’s at 6.20 Euro at the moment or ~ $7.13 USD
so I’d say we probably aren’t rich today based off of this...... but
there have been several days where the DAX trots allong up 5-10-15% then in opens in the US and bang it’s up 25% and rises from there.
