Some choices tonight at RB, I'll try and be quick. 
Javonte Williams/Mel Gordon owners likely are trying to decide with maybe the likes of Alex Collins, JD McKissic, Devontae Booker, Khalil Herbert, Myles Gaskin, you know that horrible 20-30+ group. 
I do think 
Collins is going to be fine for MNF vs the Saints, it's a home game and Seattle is going to make it their game of the year of they have any hopes of keeping things afloat until they get Wilson back...although i don't see them as Playoff contenders any more, I did sort of preseason but things have changed. 
McKissic is all over the place and at that point you might as well start talking about Kenyan Drake, anyway he is going to repeat this week? 
If you must choose between this pile this week, you might find softer defenses then you will in Cleveland.  As 
@rockaction was pointing out,
 Cleveland is like #2 vs RB and you got a split load or duties/touches, that's going to be a tall task for a guy like Williams to explode tonight. But Gordon has not been doing great of late either. 
Cheers!