Perfect Sense - Ewan McGregor and Eva Green: a global virus slowly eliminates the human senses.
Was just coming here to post about this. My wife was looking for a romance movie last night and put this on. I thought my night was going to suck. Turns out this is a really good movie. Another reminder that when people complain about Hollywood being out of new ideas, they're just not looking in the right places.
Really intriguing and well-done plot, great acting/chemistry, and really good atmosphere and music.
The movie is more about two people and their relationship amidst this crazy phenomenon (they can't tell if it's a disease or something else) than the phenomenon itself, but there is still a lot about how different parts of the world are handling it and whatnot.