Giants are at #4.
Trade down with the Browns at #7 and add their 2nd round pick (the Browns gave up the 2nd to move up 1 spot for Winslow, which means they would have definitely given it up to move up 3 spots, if not more).
At #7, take Ben Roethlisberger.
Then, in round 2 take Chris Snee and Jacob Rogers.
They also keep their 3rd, which they could have used on a DT like Randy Starks or possibly a WR like Derrick Hamilton.
Keep Kerry Collins around for 1 more year and still look forward to a 1st round pick next year.
So, Eli Manning potentially cost them: 2 1sts, a 2nd, a 3rd, and a 5th, plus it apparently made Kerry Collins unwilling to restructure and stick around...perhaps he would have stayed if Roethlisberger was the guy at #7.