After all of that this is what I've determined:
* The question of 2QB vs 3QB, 2PK vs 3PK, etc is pretty much a personal risk preference, though if you go 2QB you can't go cheap on the second one. Even with QBs being weighted at 80% the value of their projected points I find QBs being prioritized over other positions during the optimization process. I think I'm good here with my 2 QBs. Not sure how cheap is too cheap on the second one, but I'm pretty confident in my QB1 and think my QB2 is serviceable enough to fill in on the bye and maybe put up some other useful weeks.
* While kickers may seem worthless, most of the teams I've generated that applied diminishing returns to extra players at a position had high priced kickers (as a good PK1 is better than a good WR6). Same with defeneses. Generally speaking you want the primary players at all positions to be good. I do not have a high-priced kicker. But I got one that I think is decent value and two other cheapies. I'm not sure how much of a correlation there is between preseason projections and actual performance for kickers; if I could guarantee that I'd get PK1 by spending $7 on one, it might be worth it, but I don't think that's possible. I'd rather spend that $7 on three different kickers, who each have a chance to put up starter-worthy points on any given week.
* There are 3-4 players that appear in a vast majority of teams regardless of scoring and weighting. One of them is Denarius Moore. Curious who they are. I have Moore. I probably have most of the others, too. I've relied heavily on FBG projections and Shark Pool wisdom this year.
* In teams generated with diminishing returns there are around 10 primary players. Not sure exactly what you mean by primary players. I have probably 8-10 guys who I expect to be regular contributors, and then a bunch of upside guys.
* You don't need to worry about players with a bye-week of 5. Almost all teams generated had poor performance that week, and most of the best ones I generated had a huge number of players on bye that week, in fact most of the best teams I've seen so far have only had the two worst RBs on the team playing that week. You do however need to have several players with good match-ups to counteract the players off that week, though it does seem to the be the "safest" week to have most of your studs off. I have, by far, the most players off in week 5, so this is comforting. I figured many other people would also have week 5 bye issues, and that it's early enough in the season to survive despite missing some key players.
* RB is a disaster position this year. There's not much in terms of value at that position and the "best value" players are not players you may want. If you are looking for a position where you want to focus finding a long shot or using your gut to make a choice this is where you want to focus. That's pretty much how my RBs shook out. Until earlier today I had $17 Cedric Benson slotted as my RB1, but finally decided to get rid of him and use that $17 elsewhere. Lots of risk/reward in my RB corps.
My advice to everyone playing is find value in every position other than RB, and forget projections at the RB position and just find the most cost-effective players you can that have a chance of breaking big this season. Given RB is the hardest to find value at it's probably going to be the biggest dollar-to-dollar difference maker.