Plant-based diet is not the same thing as vegan or vegetarian.
The concept is: Most calories come from veggies. That's it.
You can have a sausage pizza today, and a steak next week, and still be eating a plant-based diet.
Yeah, and this could be a good thread if we don’t have these arguments. Eliminate sugar and complex carbs - those two things alone are much bigger issues than whether somebody eats some animal protein or is vegan.
ETA - I’m a moron - meant processed carbs and not complex carbs.
While I don't think we should ignore diet in the longevity equation, clearly it's a polarizing topic, with a lot of conflicting messaging based on imperfect data.
What about supplements? I know taurine has a thread somewhere, and there will likely be a study with metformin, if it gets funding. One of the longevity book authors takes NMN. I've been told there's a black market for off-label rapamycin as well.
Anyone take stuff purported to extend lifespan?
I read Lifespan (the David Sinclair one) and got very intrigued. Even if he's 20% correct, it's pretty exciting about the science and potential therapeutic interventions.
I have been taking NMN daily. I did notice a positive benefit on energy, but it leveled off pretty quickly. I buy from Amazon and the suppliers of NMN go in and out of stock a lot. I switched to a version that had NMN plus reservatol. Over a few weeks, I started having GI issues. After a month of that, I was start to wonder if I had colon cancer or something. Anyway, I had a lightbulb moment that GI issues started might be related. I quit taking any of that and my stools are happy again. I hope that doesn't cut my life expectancy.
On his other recommendations (calorie restrictions, cold therapy, fasting sessions, other supplements, exercise, mostly plant diet, cutting sugar/sweets), I haven't adopted much outside of cutting red meat down a lot. In my own foray into longevity studies years ago, it seemed like every epidemiological study supported the basics of "don't be fat and exercise regularly". So I stick with that. I ought to do more, but I don't sweat it nowadays.
Yeah, Sinclair is the most bullish of the authors concerning what the future holds for human longevity. Arguably, he’s also the most qualified to describe the state of the science.
He believes there will be meaningful breakthroughs to promote longevity within our lifetimes, including extending our biologic age limit up to ~150. He also takes NMN, resveratrol, and acknowledges the value of protein restriction, in contrast to Attia (He takes low dose rapamycin IIRC, plus B vitamins, D, fish oil, aspirin, probiotics and protein powder).
His research has been criticized though, and he has financial stake in the supplements he advocates.
Potential for secondary gain aside, I hope at least a few of his predictions come to fruition. If some of what he says is truly around the corner, we all ought to do everything in our power to stick around as long as possible.
On the other hand, there are many potential issues with an even bigger aging population. Not sure our country, or the planet can handle it.